Results 141 to 150 of about 5,128,022 (309)

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

open access: yesNature, 2014
Roy S. Herbst   +21 more
semanticscholar   +1 more source

Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining

open access: yesNature Communications
We describe a process for rapid antibody affinity optimization by repertoire mining to identify clones across B cell clonal lineages based on convergent immune responses where antigen-specific clones with the same heavy (VH) and light chain germline ...
Yi-Chun Hsiao   +14 more
doaj   +1 more source

Human antibody responses to the plamodium vivax duffy binding protein in Sri Lanka

open access: yes, 2004
Recombinant protein DBP, expressed in a bacculoviral vector, representing the native Plasmodium vivax Duffy Binding Protein (DBP) was used in an indirect ELISA to assay the total anti-DBP antibody (IgM + IgG) responses in Sri Lankan patients with acute ...
Udagama-Randeniya, P.V.   +1 more
core  

Neutralization of budded Autographa californica NPV by a monoclonal antibody: identification of the target antigen. [PDF]

open access: yes, 1984
A neutralizing monoclonal antibody of the budded phenotype of Autographa californica nuclear polyhedrons virus did not react with the occluded form of the virus as determined by neutralization, ELISA, and indirect immunoperoxidase staining.
Faulkner, P   +3 more
core  

Increased stable integration efficiency in CHO cells through enhanced nuclear localization of Bxb1 serine integrase

open access: yesBMC Biotechnology
Background Mammalian display is an appealing technology for therapeutic antibody development. Despite the advantages of mammalian display, such as full-length IgG display with mammalian glycosylation and its inherent ability to select antibodies with ...
Olli Huhtinen   +4 more
doaj   +1 more source

Immunogenicity Assessment of a 14-Valent Human Papillomavirus Vaccine Candidate in Mice

open access: yesVaccines
Background: Cervical cancer ranks as the fourth most common cancer affecting women globally, with HPV as the primary etiology agent. Prophylactic HPV vaccines have substantially reduced the incidence of cervical cancer.
Lei Bei   +13 more
doaj   +1 more source

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