Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura+7 more
wiley +1 more source
RETRACTION: Antibody Immune Responses and Causal Relationships in Four Immune Skin Diseases: Evidence From Mendelian Randomization and Bayesian Weighting (Antibody Responses in Skin Diseases: MR & Bayesian). [PDF]
europepmc +1 more source
Reduction of extracellular vimentin in blood provides protection against SARS-CoV-2 infection. [PDF]
Kim HM+5 more
europepmc +1 more source
The Occurrence of Antibodies for Pneumococcus Type II in the Serum of Normal Rabbits
Joaquin Munoz, Frances E. Holford
openalex +1 more source
Key role for inhibins in effective T cell activation, migration and Th17 differentiation
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco+5 more
wiley +1 more source
Design and development of a bispecific antibody targeting BAFF and IL-17 for systemic lupus erythematosus treatment. [PDF]
Xin C+9 more
europepmc +1 more source
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado+4 more
wiley +1 more source
Advancing Antibody Titer Assessment in ABO-Incompatible Transplantation. [PDF]
Tasaki M, Saito K, Takahashi K.
europepmc +1 more source
THE RELATION OF ANTI-LEUKOCYTE ANTIBODIES TO THE HOMOGRAFT REACTION
Roy L. Walford
openalex +1 more source