Results 211 to 220 of about 79,837 (298)

Table S4 from Site-Specific Dolasynthen Antibody–Drug Conjugates Exhibit Consistent Pharmacokinetic Profiles across a Wide Range of Drug-to-Antibody Ratios [PDF]

Susan M. Clardy, Alex Uttard, Bingfan Du, Kalli C. Catcott, Kelly L. Lancaster, Elizabeth Ditty, Jack Sadowsky, Jeffrey Zurita, Naniye Malli, LiuLiang Qin, Stephen P. Bradley, Kenneth Avocetien, Tyler Carter, Dokyong Kim, Mark Nazzaro, Ling Xu, Thomas H. Pillow, Neelie T. Zacharias, Gail D. Lewis Phillips, Rebecca K. Rowntree, Radha Iyengar, David H. Lee, Marc Damelin, Dorin Toader, Timothy B. Lowinger   +24 more
openalex   +1 more source

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

Advanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta, Sofia Peressotti, Roberto Portillo‐Lara, Josef Goding, Rylie Green   +4 more
wiley   +1 more source

A Novel FGFR3-Targeting Antibody-Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS-STING Pathway in Bladder Cancer. [PDF]

Adv Sci (Weinh)
Cui S, Luo X, Fan G, Jiang J, Wang Y, Yang E, Ma J, Zhang Z, Wang Y, Wang J, Wang D, Wang H, Cheng L, Tian J, Dong Z, Liu Y, Wang Z.   +16 more
europepmc   +1 more source

High‐Resolution Characterization of Protein‐Conjugated, mRNA‐Loaded Lipid Nanoparticles by Analytical Ultracentrifugation

Advanced Functional Materials, EarlyView.
Lipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Sophia Bird, Connor Smith, Nahal Habibi, Samantha Rivera, Saeed Mortezazadeh, Reece Martin, Benjamin M. Geilich, Gilles Besin, Borries Demeler   +8 more
wiley   +1 more source

Adverse events induced by the subcutaneous HER2-targeted antibody-drug conjugate JSKN033 in a male patient with breast cancer: A case report. [PDF]

Oncol Lett
Yang R, Zhang J, Wang Y.
europepmc   +1 more source

ICAM‐1 Is Overexpressed by Cancers and Negatively Impacts Antibody‐Based Therapies Including Antibody–Drug Conjugates [PDF]

J. Bradford Kline, Luigi Grasso, Nicholas C. Nicolaides   +2 more
openalex   +1 more source

Cold Quad‐Modal Nanocomplex for Precise and Quantitative In Vivo Stem Cell Tracking

Advanced Functional Materials, EarlyView.
Multimodal albumin–bismuth sulfide–superparamagnetic iron oxide (ABS) nanocomplexes are developed for stem cell tracking across four different imaging modalities: MRI, MPI, MSOT, and CT. Combining its flexibility with high sensitivity, this quad‐modal imaging agent enables a robust quantification of ABS‐labeled stem cells in vivo.
Ali Shakeri‐Zadeh, Chao Wang, Shreyas Kuddannaya, Saleem Yousf, Jeff W. M. Bulte   +4 more
wiley   +1 more source

Anti-lipolysis-stimulated lipoprotein receptor antibody-drug conjugate to treat triple-negative breast cancer. [PDF]

Front Oncol
Zhou ZZ, Ballard D, Varadkar T, Zhang J, Du Z, George A, Krabacher A, Yengo R, Zhou L, Liu XM.   +9 more
europepmc   +1 more source

Antibody-drug Conjugate MEDI7247 [PDF]

, 2020
openaire   +1 more source

Laser‐Microscribed Glass Enables Surface‐Microfluidics‐Facilitated, Affordable, Rapid Cancer Diagnosis

Advanced Functional Materials, EarlyView.
A transparent, laser‐microscribed glass platform enables cancer diagnosis within 1 h—much faster than histology, which takes days, and free from the chemical or contrast risks of MRI or CT scans. The antibody‐functionalized rough glass surface captures viable cancer cells directly from suspension, allowing instant optical readout and offering a rapid ...
Anish Pal, Snehasis Mishra, Arani Mukhopadhyay, Ilias Papailias, Atique U. Ahmed, Constantine M. Megaridis   +5 more
wiley   +1 more source