Results 201 to 210 of about 411,227 (332)

hAb-Convergent: an antibody rearrangement analysis system for therapeutic antibody engineering based on convergent evolution. [PDF]

Nucleic Acids Res
Wang J, Ge X, Sun Q, Chen M, Qin S, Liu D, Deng T, Ma J, Hu S, Jin R, Tong Z, Wu L.   +11 more
europepmc   +1 more source

Engineering more efficacious antibody therapy for myeloma [PDF]

, 2014
Frits van Rhee
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Targeting acute myeloid leukemia through antibody engineering: innovations in immunotherapy and combination regimens. [PDF]

Clin Exp Med
Soleimani Samarkhazan H, Noormohamadi H, Shafiei FS, Taghinejad Z, Maleknia M, Raoufi A, Nouri S, Mohammadi MH.   +7 more
europepmc   +1 more source

Engineering antibody fragments to fold in the absence of disulfide bonds

, 2009
Min Jeong Seo, Ki Jun Jeong, Clinton E. Leysath, Andrew D. Ellington, Brent L. Iverson, George Georgiou   +5 more
openalex   +1 more source

Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling [PDF]

, 2015
Shahir S. Rizk, Jean-Louis K. Kouadio, Anna Szymborska, E.M. Duguid, Somnath Mukherjee, Jiamao Zheng, Charles V. Clevenger, Anthony A. Kossiakoff   +7 more
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Structure-guided bispecific antibody engineering confers broad protection against KP.3.1.1 and sarbecoviruses. [PDF]

iScience
Ma Y, Liu Q, Rehati P, Zhang Z, Wang Y, Liu Z, Chen J, Bai X, Hao A, Wang Y, Wen Y, Chen Z, Lu L, Zhao J, Wu F, Sun L, Huang J.   +16 more
europepmc   +1 more source

Engineering and characterization of a baculovirus-expressed mouse/human chimeric antibody against transferrin receptor

, 2009
Xiantao Shen, G.-b. Hu, S.-j. Jiang, Fengrong He, Xing Wei, Jiawei Li, H. J. Yang, Hucheng Zhu, Ping Lei, Guanxin Shen   +9 more
openalex   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source