Results 171 to 180 of about 1,554,946 (301)

Development and Validation of a Machine Learning Model to Predict Anti-Drug Antibody Formation During Infliximab Induction in Crohn's Disease. [PDF]

Biomedicines
Wang Y, Song J, Zheng Z, Peng X, Li X, Wu W.   +5 more
europepmc   +1 more source

Polygenic genetic variation affecting antibody formation underlies hypertensive renal injury in the stroke-prone spontaneously hypertensive rat.

Am J Physiol Renal Physiol, 2023
Dhande IS, Zhu Y, Joshi AS, Hicks MJ, Braun MC, Doris PA.   +5 more
europepmc   +1 more source

IgG and IgM antibody formation to spike and nucleocapsid proteins in COVID-19 characterized by multiplex immunoblot assays. [PDF]

BMC Infect Dis, 2021
Shah J, Liu S, Potula HH, Bhargava P, Cruz I, Force D, Bazerbashi A, Ramasamy R.   +7 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Pooled Incidence of Heparin-Induced Thrombocytopenia and Anti-Platelet Factor 4 Antibody Formation Among Adults: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Devarapalli A, Rachamanti R, Singampalli M, Hullur K.   +3 more
europepmc   +1 more source

Nonhuman glycans can regulate anti-factor VIII antibody formation in mice.

Blood, 2022
Arthur CM, Zerra PE, Shin S, Wang J, Song X, Doering CB, Lollar P, Meeks S, Stowell SR.   +8 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Interaction of Clinical Factors Modestly Predict Anti-TNF-Alpha Antibody Formation in a Real-World Cohort of Inflammatory Bowel Disease Patients. [PDF]

Biomedicines
Kovács K, Nagypál P, Vásárhelyi B, Dezsőfi-Gottl A, Béres N, Miheller P, Iliás Á, Balogh A, Prehoda B, Tóbi L, Szabó A, Cseh Á.   +11 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Understanding and addressing anti-drug antibody formation in tumor necrosis factor-α inhibitor therapy for ankylosing spondylitis. [PDF]

J Rheum Dis
Kim TJ.
europepmc   +1 more source