Results 321 to 330 of about 10,170,244 (414)

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Facile Immunoassay Constructed by Gold Nanostar-Labeled Rabbit-AFP Antibody and Gold Nanoparticle-Conjugated Goat Anti-Rabbit IgG. [PDF]

Nanomaterials (Basel)
Yang K, Yang F, Lu X, Li H, Yang Z, Yin Q, Zhang L, Long Y, Shen C, Chen L, Yao B, Huang C.   +11 more
europepmc   +1 more source

Antibody plaque-forming cells in unsensitized mice. Specificity and response to neonatal thymectomy, X-irradiation and PHA

, 1968
John S. Hege, L J Cole
openalex   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Comparative evaluation of three anti-dsDNA antibody detection methods in systemic lupus erythematosus: insights from a large monocentric cohort. [PDF]

Front Immunol
Lu R, Yu R, Huang R, Xue C, Song N, Zhao J, Zeng X, Hu C.   +7 more
europepmc   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Novel single-chain fragment variable antibody targeting plasma membrane epitopes on porcine Y-chromosome-bearing sperm. [PDF]

Sci Rep
Thongkham M, Hongsibsong S, Mekchay S, Sathanawongs A, Cao XM, Xu ZL, Sringarm K.   +6 more
europepmc   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Oriented Surface Immobilization of Antibodies Using Enzyme-Mediated Site-Specific Biotinylation for Enhanced Antigen-Binding Capacity. [PDF]

Langmuir
Beitello E, Osei K, Kobulnicky T, Breausche F, Friesen JA, Driskell JD.   +5 more
europepmc   +1 more source

Plasma IgG and IgM autoantibodies to COPT1 as potential biomarkers for detection of non-small cell lung cancer. [PDF]

Front Immunol
Cao X, Li J, Liu S, Liu A, Zhang L, Chen F, Li Y, Ma H, Sun W, Ouyang S, Dai L, Liu J.   +11 more
europepmc   +1 more source