Results 331 to 340 of about 10,530,811 (405)

Anticancer activity of triterpene glycosides from the sea star Solaster pacificus. [PDF]

Sci Rep
Dyshlovoy SA, Hauschild J, Kriegs M, Hoffer K, Burenina OY, Strewinsky N, Malyarenko TV, Kicha AA, Ivanchina NV, Stonik VA, Graefen M, Bokemeyer C, von Amsberg G.   +12 more
europepmc   +1 more source

Mitochondria‐Targeted Nanomotor: H2S‐Driven Cascade Therapy for Hepatocellular Carcinoma

Advanced Materials, EarlyView.
A mitochondrial‐targeted nanomotor integrates photodynamic therapy, mild photothermal therapy, and enzyme dynamic therapy into a self‐amplifying cascade through H2S‐driven metabolic reprogramming. Abstract Despite advances in combination therapies for cancer treatment, most strategies rely on modular‐additive designs that lack dynamic molecular cues to
Chengcheng Li, Xiaodong Ma, Shiji Fang, Biao Chen, Xinru Wang, Lingyun He, Xin Yang, Yuanqiang Li, Jessica M. Rosenholm, Zhongwei Zhao, Jiansong Ji, Hongbo Zhang   +11 more
wiley   +1 more source

Anticancer Activity of Ether Derivatives of Chrysin. [PDF]

Molecules
Sokal A, Mruczek P, Niedoba M, Dewalska A, Stocerz K, Kadela-Tomanek M.   +5 more
europepmc   +1 more source

Recent Advances in Collective Behaviors of Micro/Nanomotor Swarms

Advanced Materials, EarlyView.
This review describes the driving forces behind collective motion, explores the self‐organization of micro/nano swarms across zero‐dimensional (0D), one‐dimensional (1D), two‐dimensional (2D), and three‐dimensional (3D) spaces, and highlights their potential in drug delivery, environmental monitoring, and smart devices.
Siwen Sun, Bingbing Sun, Alexander B. Cook, Tania Patiño Padial, Jan C. M. van Hest   +4 more
wiley   +1 more source

Autonomous Hydrogel Actuators Programmed by Endogenous Biochemical Logic for Dual‐Stage Morphing and Drug Release

Advanced Materials, EarlyView.
A 3D‐printed BSA–PEGDA bilayer actuator performs biochemical logic, bending autonomously in acid and releasing its drug payload only when both acid and pepsin are present. This dual‐stage, enzyme‐gated mechanism enables autonomous catch‐and‐release motion and controlled gastric drug delivery, representing a programmable soft material powered by ...
Yuchen Liu, Harischandra Potthuri, Alejandro Sosnik, Luai R. Khoury   +3 more
wiley   +1 more source

Targeting RNA polymerase I to boost natural killer cell anticancer activity in multiple myeloma. [PDF]

Cell Death Dis
Sproviero E, Gnocchini E, Cipollone T, Petillo S, Cassone C, Molfetta R, Zingoni A, Soriani A, Cerboni C, Petrucci MT, Fazio F, Paolini R, Palmieri G, Cippitelli M.   +13 more
europepmc   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

Advanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim, Wonseok Choi, Yurim Kim, Hyeongmin Kim, Gu Won Jeong, Hyewon Park, Inchan Youn, Yoon Park, Sungmin Han, Young‐Min Kim   +9 more
wiley   +1 more source

Anticancer Activity of 2,3'-Dihydroxy-5'-Methoxystilbene Against NSCLC Cell Lines Through AKT-Dependent Mechanisms: A Comprehensive In Vitro and Computational Analysis. [PDF]

Int J Mol Sci
Pouyfung P, Lertnitikul N, Ogino N, Chookaew A, Pongrakhananon V, Chonsut P, Sueangoen N, Chaisit S.   +7 more
europepmc   +1 more source

DNA Origami‐Templated Aptamer Chiral Structures Realize Cellular Enantioselectivity

Advanced Materials, EarlyView.
Aptamers displayed on tubular DNA origami nanostructures in defined chiral orientations (left‐ or right‐handed) exhibit enantioselective interactions with cell surface target proteins. While the right‐handed configuration supports only transient binding, the left handedness energetically favors protein dimerization and promotes subsequent ...
Tingjie Song, Abhisek Dwivedy, Dhanush Gandavadi, Gayatri Chandran, Yiquan An, Mengxi Zheng, Xiaojing Wang, Lifeng Zhou, Yang Zhao, Xing Wang   +9 more
wiley   +1 more source

Synthesis and <i>In Vitro</i> Evaluation of Anticancer Activity of Fluorophenyl Derivatives of 1,3,4-Thiadiazole Against Estrogen-Dependent Breast Cancer. [PDF]

Molecules
Janowska S, Makuch-Kocka A, Kurczab R, Demchuk OM, Wujec M.   +4 more
europepmc   +1 more source