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Ascorbigen and other indole-derived compounds from Brassica vegetables and their analogs as anticarcinogenic and immunomodulating agents

Pharmacology & Therapeutics, 1993
Searches for the natural compounds that determine the anticarcinogenic properties of a cruciferous-vegetable diet, revealed the products of alkaloid glucobrassicin biotransformations; among these, ascorbigen, an indole-containing derivative of L-ascorbic acid, was found to be the most abundant.
A M Korolev
exaly   +3 more sources

Natural Lignans Honokiol and Magnolol as Potential Anticarcinogenic and Anticancer Agents. A Comprehensive Mechanistic Review

Nutrition and Cancer, 2021
Plant lignans constitute an important group of polyphenols, which have been demonstrated to significantly induce cancer cell death and suppress cancer cell proliferation with minimal toxicity against non-transformed cells. Numerous epidemiological studies have shown that the intake of lignans is associated with lower risk of several cancers.
Sayeh, Mottaghi, Hassan, Abbaszadeh
openaire   +2 more sources

Implications of DNA-acting Agents as Anticarcinogenic Potential in Breast Cancer Therapeutics

2023
Breast cancer is the most prevalent neoplasm diagnosed in women worldwide. There are many factors responsible for breast cancer susceptibility. Mutation in tumor suppressor genes BRCA1 and BRCA2 predispose women to the early onset of breast cancer.
Lovely Sinha, Ujjwal Kumar
openaire   +1 more source

Naturally Occurring Phenolics as Antimutagenic and Anticarcinogenic Agents

1984
Epidemiological evidence points to an inverse relationship between the consumption of vegetables and the incidence of cancer at various sites (Hirayama, 1979, 1981; Graham et al., 1978; Mettlin et al., 1981). The search for the protective components in these vegetables has focused on B-carotene and vitamin A (e.g., Bjelke, 1975; Shekelle et al., 1981 ...
H F, Stich, M P, Rosin
openaire   +2 more sources

A comprehensive mechanistic insight into the dietary and estrogenic lignans, arctigenin and sesamin as potential anticarcinogenic and anticancer agents. Current status, challenges, and future perspectives

Critical Reviews in Food Science and Nutrition, 2021
A large body of evidence indicates that lignans as polyphenolic compounds are beneficial against life-threatening diseases such as cancer. Plant lignans have the potential to induce cancer cell death and interfere with carcinogenesis, tumor growth, and metastasis.
Sayeh, Mottaghi, Hassan, Abbaszadeh
openaire   +2 more sources

Comparison of 3 Upper Tract Anticarcinogenic Agent Delivery Techniques in an Ex Vivo Porcine Model

Urology, 2013
To evaluate the degree of urothelial exposure using 3 upper tract delivery techniques in an ex vivo porcine model, to determine the optimal modality to locally deliver topical anticarcinogenic agents in patients with upper tract urothelial carcinoma.An indigo carmine solution was infused into en bloc porcine urinary tracts to test the 3 techniques ...
Matthew E, Pollard   +7 more
openaire   +2 more sources

Voltammetric behaviour and square-wave voltammetric determination of the potent antioxidant and anticarcinogenic agent ellagic acid in foodstuffs

Food Chemistry, 2011
The voltammetric behaviour of ellagic acid (EA) is investigated by cyclic, differential pulse and square-wave voltammetry (CV, DPV and SWV, respectively). Based on the anodic oxidation peak at approximately 0.42V in acetic/acetate buffer (pH 5.5) a robust and a highly reliable square-wave voltammetric method is presented for the determination of EA ...
M, Cuartero   +5 more
openaire   +2 more sources

Gallate–Zn–Al-layered double hydroxide as an intercalated compound with new controlled release formulation of anticarcinogenic agent

Journal of Physics and Chemistry of Solids, 2010
A new organic-clay material, in which the organic moiety is intercalated into the inorganic interlayer, was prepared using gallate anion (GA) as a guest, and Zn–Al-layered double hydroxide, as clay host. The ion-exchange technique was found to be effective for the intercalation process in the formation of the compound.
Ghotbi, Mohammad Yeganeh   +1 more
openaire   +1 more source

[Antimutagens and anticarcinogenic agents, identification and mechanisms of action of food xenobiotics].

Therapie, 2003
Antimutagens and anticarcinogens are natural or synthetic substances able to inhibit or to reduce spontaneous or induced DNA alteration. These inhibitors act at different levels from the penetration of the xenobiotic to the expression of the mutation and cancer. They act in extracellular and intracellular levels; they react directly with mutagens or on
R, el Hamss, M, Idaomar
openaire   +1 more source

Synthesis, characterization, photophysical and photochemical properties of zinc and indium phthalocyanines bearing a vanillylacetone moiety known as an anticarcinogenic agent

Polyhedron, 2015
Abstract The synthesis of novel peripherally/non-peripherally tetra and octa vanillylacetone-substituted zinc and indium phthalocyanines was performed by cyclotetramerization of 4-[2-methoxy-4-(3-oxobutyl)phenoxy]phthalonitrile ( 1 )/3-[2-methoxy-4-(3-oxobutyl)phenoxy]phthalonitrile ( 2 ) and 4,5-bis[2-methoxy-4-(3-oxobutyl)phenoxy]phthalonitrile ( 3
Kıyak, Bülent   +2 more
openaire   +2 more sources

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