Results 31 to 40 of about 3,277,334 (211)

Autophagy: Mechanisms and Therapeutic Potential of Flavonoids in Cancer

Biomolecules, 2021
Autophagy, which is a conserved biological process and essential mechanism in maintaining homeostasis and metabolic balance, enables cells to degrade cytoplasmic constituents through lysosomes, recycle nutrients, and survive during starvation.
Xuening Pang, Xiaoyi Zhang, Yuhuan Jiang, Quanzhong Su, Qun Li, Zichao Li   +5 more
doaj   +1 more source

Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells

Phytomedicine Plus, 2021
Background: Skin cancer is the most common type of malignancy in light-skinned populations and phenolics are promising anticarcinogenic agents. Purpose: To characterise and evaluate the protective potential of apple extracts against the DNA damage caused
Chirle de Oliveira Raphaelli, Jéssica Gonçalves Azevedo, Elisa dos Santos Pereira, Juliana Rocha Vinholes, Taiane Mota Camargo, Jessica Fernanda Hoffmann, Jardel Araújo Ribeiro, Márcia Vizzotto, César Valmor Rombaldi, Márcia Rosângela Wink, Elizandra Braganhol, Leonardo Nora   +11 more
doaj   +1 more source

Herbs in Oral Mucositis [PDF]

Journal of Clinical and Diagnostic Research, 2017
Oral mucositis is an inflammatory mucosal destruction as a result of chemotherapy and/or radiation therapy, which in severe cases can impair patients’ quality of life.
Maryam Baharvand, Soudeh Jafari, Hamed Mortazavi   +2 more
doaj   +1 more source

Melatonin as a Repurposed Drug for Melanoma Treatment

Medical Sciences, 2023
Melanoma is the most aggressive type of skin cancer, with a greater risk of metastasis and a higher prevalence and mortality rate. This cancer type has been demonstrated to develop resistance to the known treatment options such as conventional ...
Rachana Pathipaka, Anita Thyagarajan, Ravi P. Sahu   +2 more
doaj   +1 more source

Copper(II) Complex Containing 4-Fluorophenoxyacetic Acid Hydrazide and 1,10-Phenanthroline: A Prostate Cancer Cell-Selective and Low-Toxic Copper(II) Compound

Molecules, 2022
Prostate Cancer (PCa) is the second leading cause of cancer-related deaths among men worldwide. The treatment of advanced cases is based on chemotherapy, which lacks specificity and efficacy, due to severe side effects and resistance to the traditional ...
Nayara Júnia de Souza Bontempo, Drielly Aparecida Paixão, Paula Marynella Alves Pereira Lima, Deysse Carla Tolentino Barros, Dayanne Silva Borges, Priscila Capelari Orsolin, Isabella Castro Martins, Pedro Henrique Alves Machado, Ricardo Campos Lino, Tiago Rodrigues de Souza, Luana Munique Sousa Ramos, Samuel Cota Teixeira, Raoni Pais Siqueira, Luiz Ricardo Goulart Filho, Wendell Guerra, Robson José de Oliveira Júnior, Thaise Gonçalves de Araújo   +16 more
doaj   +1 more source

Independent and joint cross-sectional associations of statin and metformin use with mammographic breast density

Breast Cancer Research, 2020
Background Well-tolerated and commonly used medications are increasingly assessed for reducing breast cancer risk. These include metformin and statins, both linked to reduced hormone availability and cell proliferation or growth and sometimes prescribed ...
Erica J. Lee Argov, Teofilia Acheampong, Mary Beth Terry, Carmen B. Rodriguez, Mariangela Agovino, Ying Wei, Shweta Athilat, Parisa Tehranifar   +7 more
doaj   +1 more source

Diversity of Chromanol and Chromenol Structures and Functions: An Emerging Class of Anti-Inflammatory and Anti-Carcinogenic Agents

Frontiers in Pharmacology, 2020
Natural chromanols and chromenols comprise a family of molecules with enormous structural diversity and biological activities of pharmacological interest.
Maria Wallert, Stefan Kluge, Martin Schubert, Andreas Koeberle, Andreas Koeberle, Oliver Werz, Marc Birringer, Marc Birringer, Stefan Lorkowski, Stefan Lorkowski   +9 more
doaj   +1 more source

A novel radiolytic rotenone derivative, rotenoisin A, displays potent anticarcinogenic activity in breast cancer cells

Journal of Radiation Research, 2021
Chemotherapy for cancer treatment has therapeutic limitations, such as drug resistance, excessive toxic effects and undesirable adverse effects. Therefore, efforts to improve the safety and efficacy of chemotherapeutic agents are essential.
Dong-Ho Bak, S. Kang, Chul-hong Park, B. Chung, Hyoung-Woo Bai   +4 more
semanticscholar   +1 more source

Synthesis and Biological Evaluation of Novel Isoxazole-Amide Analogues as Anticancer and Antioxidant Agents

BioMed Research International, 2021
Cancer now is one of the leading causes of mortality in the world. There has been a lot of effort to discover new anticarcinogenic agents that allow treatment with fewer side effects. A series of isoxazole-carboxamide derivatives (2a–2g) were synthesised
A. Eid, Mohammed Hawash, J. Amer, Abdullah Jarrar, Samira Qadri, Iman Alnimer, Aya Sharaf, Raya Zalmoot, Osama Hammoudie, S. Hameedi, A. Mousa   +10 more
semanticscholar   +1 more source

Natural Polyphenols for Treatment of Colorectal Cancer

Molecules, 2022
Colorectal cancer (CRC) is a prevalent and serious gastrointestinal malignancy with high mortality and morbidity. Chemoprevention refers to a newly emerged strategy that uses drugs with chemopreventive properties to promote antioxidation, regulate cancer
Yiwen Zhang, Kunjian Liu, Chengqiu Yan, Yu Yin, Shuangyan He, Li Qiu, Guofeng Li   +6 more
doaj   +1 more source