Results 61 to 70 of about 493,734 (206)

Estimation of Antiphospholipid Antibodies, Anticardiolipin Antibodies, Beta-2 Glycoprotein 1 Antibodies in Recurrent Pregnancy Loss - A Case-control Study [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Recurrent miscarriage is the occurrence of three or more consecutive pregnancy loss before 20 weeks of gestation. Antiphospholipid Antibodies (APAs) are one of the causes responsible for recurrent pregnancy loss.
Nilam Bhasker, Meenakshi Kar, Dharmendra Kumar   +2 more
doaj   +1 more source

Thromboinflammatory biomarkers in obstetric pathophysiology: Predictive insights into placental insufficiency and feto‐maternal adverse outcomes

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Placental insufficiency is a thromboinflammatory disorder driven by angiogenic imbalance, complement activation, endothelial dysfunction and coagulation dysregulation, leading to microvascular thrombosis, impaired uteroplacental perfusion and adverse maternal and fetal outcomes, including pre‐eclampsia, fetal growth restriction and stillbirth. Abstract
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Using Preoperative Therapeutic Plasma Exchange in Lupus Anticoagulant Hypoprothrombinemia Syndrome to Achieve Hemostatic Factor II Activity: A Case Report

Journal of Clinical Apheresis, Volume 41, Issue 4, August 2026.
ABSTRACT Lupus anticoagulant hypoprothrombinemia syndrome (LA‐HPS) is a rare cause of acquired factor II deficiency associated with lupus anticoagulant due to antiprothrombin antibody, which predisposes to bleeding rather than thrombosis. We report a case of a 48‐year‐old female with LA‐HPS resulting in a bleeding diathesis due to acquired prothrombin ...
Puja Panwar, Sean G. Yates, Rebecca Yarborough, Yu‐Min Shen   +3 more
wiley   +1 more source

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

Journal of Clinical Laboratory Analysis, Volume 40, Issue 15, August 2026.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka, Risa Kaneshige, Seika Nakamura, Yukari Motoki, Junzo Nojima   +4 more
wiley   +1 more source

Deep capillary retinal ischemia and high-titer prothrombin-associated antiphospholipid antibodies: A case series of three patients

American Journal of Ophthalmology Case Reports, 2019
Purpose: Acute macular neuroretinopathy has been shown to be due to ischemia of the deep capillary retinal plexus and most cases occur in young women; we hypothesized that there may be an association with antiphospholipid antibodies.
Jill R. Schofield, Alan G. Palestine, Victoria Pelak, Marc T. Mathias   +3 more
doaj   +1 more source

Determination and Correlation of Anticardiolipin Antibody with High Sensitivity C- reactive Proteins and its Role in Predicting Short Term Outcome in Patients with Acute Coronary Syndrome [PDF]

, 2011
Anticardiolipin antibody (aCL) is considered to be an independent risk factor while high sensitivity C reactive protein (hsCRP) is an established marker for coronary artery disease. This study was conducted to determine levels of aCL antibodies and hsCRP,
Kapoor, N, Malhotra, AS, Gupta, V, Kashyap, JR, Mehta, J, Sharma, R, Sachdev, A   +6 more
core  

Australian clinical practice guideline: diagnosis and treatment of idiopathic multicentric Castleman disease

Internal Medicine Journal, Volume 56, Issue 7, Page 1218-1239, July 2026.
Abstract Idiopathic multicentric Castleman disease (iMCD) is a rare condition. The pathogenesis is incompletely understood; however, interleukin‐6 (IL‐6) is a major mediator. The clinical presentation is heterogeneous, from mild constitutional symptoms to severe multi‐organ failure.
Dipti Talaulikar, Jun Yen Ng, Adam Bryant, Annmarie Bosco, Hugh C. Caterson, Pratyush Giri, Pravin Hissaria, Simon J. Harrison, Stephen Lade, Connull Leslie, Jacinta Perram, H. Miles Prince, Dejan Radeski, Maureen Rischmueller, Craig Wallington‐Gates, Nicholas Weber, Alberta Hoi   +16 more
wiley   +1 more source

PATHOGENIC SERUM IGG ANTICARDIOLIPIN ANTIBODIES AND THE IDIOTYPIC NETWORK

, 1993
OBJECTIVES: To determine whether active immunisation of mice with pathogenic anticardiolipin antibodies (IgG and IgM), derived from the serum of a patient with the antiphospholipid syndrome, could dysregulate the idiotypic cascade and induce the ...
Y. Shoenfeld, R. Bakimer, J. Cohen, M. Blank, VALESINI, Guido   +4 more
core   +1 more source

Anticardiolipin antibodies in Jamaican primiparae

Journal of Obstetrics and Gynaecology, 2006
A prevalence survey of anticardiolipin antibodies (aCL) was done among 924 primiparae. aCL were measured in serum by the standardised anticardiolipin enzyme linked immunosorbent assays (ELISA) and beta(2)-glycoprotein 1 assays to determine the seroprevalence of both beta(2) glycoprotein 1 dependent aCL and beta(2)-glycoprotein 1 independent aCL in ...
E K, Kahwa, L A, Sargeant, A, McCaw-Binns, N, McFarlane-Anderson, M, Smikle, T, Forrester, R, Wilks   +6 more
openaire   +2 more sources

Polyclonal Anticardiolipin Antibodies Purified from Sera of Patients with Active Systemic Lupus Erythematosus Induce Apoptosis of the Cultured Glomerular Mesangial Cells

, 2008
Objective: To test the effect of anticardiolipin antibodies( aCL) on cultured glomerular mesangial cells with regard to their expression of apoptosis-related genes.
蔡長祐;余家利;吳采虹;盧嘉瑜;廖堂順;蔡瀛陽;周昌德, TSAI, CHANG-YU;YU, CHIA-LI;WU, TSAI- HUNG;LU, CHIA-YU;LIAO, TANG-SHUN;TSAI, YI-YANG;CHOU, CHANG-TE   +1 more
core