Results 31 to 40 of about 2,723 (121)

Apolipoprotein E1-Hammersmith (Lys146 → Asn;Arg147 → Trp), due to a dinucleotide substitution, is associated with early manifestation of dominant type III hyperlipoproteinaemia [PDF]

open access: yes, 1996
Apolipoprotein E (apoE) is one of the major protein constituents of chylomicron and very low density lipoprotein (VLDL) remnants and plays a central role as a ligand in the receptor-mediated uptake of these particles by the liver.
Hoffer, M.J.V.   +6 more
core  

Subacute Therapeutic Dosing of Artemether‐Lumefantrine and Artesunate‐Amodiaquine Combination Preserves Plasma Cholesterol, Renal Antioxidant Status, and Organ Weights in Rats

open access: yesMalaria Research and Treatment, Volume 2012, Issue 1, 2012., 2012
Recent instances of breakdowns of malaria control programs and the constant emergence of drug‐resistant parasites to monotherapies have shored up the use of artemisinin‐based combination therapy (ACT) as the malaria therapy of choice. We evaluated a subacute therapeutic dosing of artemether‐lumefantrine and artesunate‐amodiaquine on plasma cholesterol,
Chiagoziem A. Otuechere   +4 more
wiley   +1 more source

Evaluation of the Biocompatibility of a Bilayer Chitosan Skin Regenerating Template, Human Skin Allograft, and Integra Implants in Rats

open access: yesInternational Scholarly Research Notices, Volume 2011, Issue 1, 2011., 2011
Introduction. Chitosan is a nontoxic, biocompatible, and biodegradable polymer obtained from chitin by N‐deacetylation using strong alkali. Chitosan in a form of a bilayer skin regenerating template can act as a scaffold for regeneration. Integra is a two‐layer skin regeneration system, constructed of a matrix of crosslinked fibers that acts as a ...
Shah Jumaat Mohd Yussof   +5 more
wiley   +1 more source

Synthesis of Silicon and Germanium Containing Heteroaromatic Sulfides as Cholesterol Level Lowering and Vasodilating Agents

open access: yesMetal-Based Drugs, Volume 8, Issue 2, Page 85-93, 2001., 2001
Silicon and germanium containing heteroaromatic sulfides have been prepared using phase transfer catalytic (PTC) system thiol / Si or Ge containing alkyl halide / solid KOH / 18‐ crown‐6 / toluene. The target sulfides were isolated in yields up to 92 %.
Kira Rubina   +5 more
wiley   +1 more source

The use of Simvastatin Plus Metformin Therapy in Patients With Polycystic Ovarian Syndrome [PDF]

open access: yes, 2012
Background: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder that affects the fertility of reproductive-aged women due to high levels of testosterone.
Carrick, Erin
core   +1 more source

The Effects of HMG-CoA Inhibitors (Statins) on Rheumatoid Arthritis Disease Progression: A Systematic Review [PDF]

open access: yes, 2012
Background: Rheumatoid arthritis is a chronic, progressive autoimmune disease that erodes joint synovium and affects other body organs and vasculature. While current therapies, designed to address the impact of rheumatoid arthritis on joints, have been ...
Johnson, Sarah Kepple
core   +1 more source

Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans [PDF]

open access: yes, 1988
The power of serum lathosterol concentration as an indicator of whole-body cholesterol synthesis was investigated in 47 human volunteers consuming two diets differing in fatty acid composition. The cholesterol balance (fecal excretion of neutral and acid
Glatz, J.F.C.   +6 more
core   +1 more source

Action of lovastatin, simvastatin, and pravastatin on sterol synthesis and their antiproliferative effect in cultured myoblasts from human striated muscle [PDF]

open access: yes, 1996
Lovastatin, simvastatin, and pravastatin are fairly strong inhibitors of sterol synthesis in human myoblasts in culture. Lovastatin and simvastatin have IC50 values of 19 ± 6 nM and 4.0 ± 2.3 nM, respectively.
Vliet, A.K. van   +4 more
core  

Rosuvastatina e ciprofibrato no tratamento da dislipidemia em pacientes com HIV Rosuvastatin and ciprofibrate in the treatment of dyslipidemia in patients with HIV

open access: yesArquivos Brasileiros de Cardiologia, 2012
FUNDAMENTO: A dislipidemia secundária à terapia antirretroviral potente nos pacientes com HIV está associada à significativa elevação da morbimortalidade cardiovascular por doença aterosclerótica, sendo, portanto, necessário tratamento imediato e eficaz.
Hamilton Domingos   +5 more
doaj  

Vastatins inhibit cholesterol ester accumulation in human monocyte-derived macrophages [PDF]

open access: yes, 1991
Human monocyte-derived macrophages were incubated for 48 hours in Medium 199 with 1% human serum albumin, and with 100 μg acetyl low density lipoprotein (LDL) or β-very low density lipoprotein (β-VLDL), with or without various concentrations of compactin,
Kempen, H.J.M.   +3 more
core  

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