Results 1 to 10 of about 83,224 (354)

Pharmacogenetic associations of CYP2D6 and CYP2C19 variants with anticholinergic drug burden and hyposalivation [PDF]

Frontiers in Pharmacology
IntroductionAnticholinergic medications frequently cause hyposalivation (decreased saliva flow) through parasympathetic inhibition. This adverse effect is related to anticholinergic burden, reflecting the cumulative exposure to drugs with anticholinergic
Olga A. Korczeniewska, Scott Diehl, Abdul Basir Barmak, Tong Tong Wu, Eli Eliav, Szilvia Arany   +5 more
doaj   +2 more sources

Understanding the medication regimens associated with anticholinergic burden in older people's mental health services in the UK [PDF]

BJPsych Open
Background Medications with anticholinergic properties are associated with a range of adverse effects that tend to be worse in older people. Aims To investigate medication regimens with high anticholinergic burden, prescribed for older adults under the ...
Thomas R. E. Barnes, Delia Bishara, Alistair Burns, Phyo K. Myint, Olivia Rendora, Elena M. Edokpolor Pernia, Carol Paton   +6 more
doaj   +2 more sources

A Retrospective Database Analysis of Anticholinergic Burden Among Older Patients With and Without Overactive Bladder in South Korea [PDF]

International Neurourology Journal
Purpose This study aimed to measure the cumulative anticholinergic burden in older outpatients in South Korea with and without newly started overactive bladder (OAB) medications, and to assess the contribution OAB treatment-related antimuscarinics have ...
Kyu-Sung Lee, Juhee Cho, Danbee Kang, Kwang Jin Ko, Chee Yoong Foo, Matthias Stoelzel, Farid Abdul Hadi, Soyoung Kim   +7 more
doaj   +2 more sources

Anticholinergic and Sedative Medication Burden in Croatian Older Adults: EuroAgeism Cohort Findings [PDF]

Pharmacy
Use of anticholinergic and sedative medications is potentially inappropriate in older adults due to associated adverse effects, including impaired cognitive and physical function.
Margita Držaić, Iva Bužančić, Ingrid Kummer, Andrea Bošković, Dragan Glavaš, Maja Ortner Hadžiabdić, Jovana Brkić, Daniela Fialová   +7 more
doaj   +2 more sources

Older patients' prescriptions screening in the community pharmacy: development of the Ghent Older People's Prescriptions community Pharmacy Screening (GheOP3S) tool [PDF]

, 2015
Background: Ageing of the population often leads to polypharmacy. Consequently, potentially inappropriate prescribing (PIP) becomes more frequent. Systematic screening for PIP in older patients in primary care could yield a large improvement in health ...
Boussery, Koen, Mehuys, Els, Petrovic, Mirko, Somers, Annemie, Tommelein, Eline, van der Cammen, Tischa   +5 more
core   +15 more sources

Development of the Swedish anticholinergic burden scale (Swe-ABS)

BMC Geriatrics, 2023
Background Drugs with anticholinergic properties are associated with cognitive adverse effects, especially in patients vulnerable to central muscarinic antagonism. A variety of drugs show weak, moderate or strong anticholinergic effects.
Tanja Rube, Astrid Ecorcheville, Elisabet Londos, Sara Modig, Per Johansson   +4 more
doaj   +1 more source

Anti-Cholinergic Drug Burden Among Ambulatory Elderly Patients in a Nigerian Tertiary Healthcare Facility

Frontiers in Pharmacology, 2021
Background: The use of drugs with anticholinergic effects among elderly patients is associated with adverse clinical outcomes. There is paucity of information about anticholinergic drug burden among Nigerian elderly population.Objectives: To determine ...
Joseph O. Fadare, Joseph O. Fadare, Abimbola Margaret Obimakinde, Abimbola Margaret Obimakinde, Felix O. Aina, Ebisola J. Araromi, Theophilus Adekunle Adegbuyi, Oluwatoba E. Osasona, Tosin A. Agbesanwa   +8 more
doaj   +1 more source

Adverse drug reactions associated with amitriptyline - protocol for a systematic multiple-indication review and meta-analysis [PDF]

, 2020
Background: Unwanted anticholinergic effects are both underestimated and frequently overlooked. Failure to identify adverse drug reactions (ADRs) can lead to prescribing cascades and the unnecessary use of over-thecounter products.
Brueckle, Maria-Sophie, Gerlach, Ferdinand M, Glasziou, Paul P, Gonzalez-Gonzalez, Ana Isabel, Harder, Sebastian, Muth, Christiane, Nguyen, Truc Sophia, Pilz, Maximilian, Seide, Svenja E, Thomas, Elizabeth T   +9 more
core   +1 more source

A meta-analysis of observational studies on anticholinergic burden and fracture risk: evaluation of conventional burden scales

Journal of Pharmaceutical Health Care and Sciences, 2021
Background Anticholinergic burden potentially increases the risk of fracture. Although there are various anticholinergic burden scales, little is known about the inter-scale compatibility regarding the relationship of anticholinergic burden with fracture
Yukari Ogawa, Toshinori Hirai, Kiyoshi Mihara   +2 more
doaj   +1 more source

Anticholinergic premedication [PDF]

Canadian Anaesthetists’ Society Journal, 1976
Two hundred and forty-four surgical patients who received no anticholinergic premedication were compared with 160 patients who had received atropine or scopolamine before the induction of anaesthesia. Infants and patients undergoing heart surgery were excluded. Eleven anaesthetists participated in the study.
K M, Leighton, H D, Sanders
openaire   +2 more sources