Results 41 to 50 of about 40,585 (248)

Antidepressant Misuse in Esports: A Review of Pharmacology, Adverse Effects, Pharmacokinetics and Biomatrix‐Based Detection for Anti‐Doping Applications

Drug Testing and Analysis, EarlyView.
This review highlights the misuse of antidepressants as potential cognitive‐enhancing agents in Esports. Despite pharmacological effects that overlap with those of psychostimulants, antidepressants remain an under‐recognised source of doping in Esports.
Kassim Ali Salum, Shao‐Hsin Hung, Meng‐Tsang Hsieh, Mei‐Chich Hsu, William Chih‐Wei Chang   +4 more
wiley   +1 more source

The association between anticholinergic load and cognitive performance, elevated blood pressure and the presence of peripheral anticholinergic side effects. [PDF]

, 2009
Background: To quantify the association between anticholinergic drug use (burden or load) and cognitive function (MMSE), blood pressure and the presence of anticholinergic side effects.Methods: The medical records of 182 aged care home residents in the ...
Puangsombat, Jiraporn, Roberts, Malcom, Hughes, Jeffery   +2 more
core   +2 more sources

Long-Term Cardiovascular Risks of Anticholinergic Versus Non-Anticholinergic Antidepressants: A Target Trial Emulation With Negative Control Correction. [PDF]

Pharmacoepidemiol Drug Saf
Purpose Antidepressants remain widely prescribed worldwide, and the potential cardiovascular risks associated with their anticholinergic properties are poorly understood ...
Xu Y, Xu H, Guo J, Her QL, Li R, Lai Y, Zhang Y, Tan ECK, Zhan S.   +8 more
europepmc   +2 more sources

Anticholinergic drugs and forebrain magnetic resonance imaging changes in cognitively normal people and those with mild cognitive impairment [PDF]

, 2022
BackgroundAnticholinergic (AC) medication use is associated with cognitive decline and dementia, which may be related to an AC induced central hypocholinergic state, but the exact mechanisms remain to be understood.
Dorothee P. Auer, Mohammadi‐Nejad, Ali‐Reza, Mohammadi-Nejad, Ali-Reza, Ali‐Reza Mohammadi‐Nejad, Meng, Dewen, Sotiropoulos, Stamatios N., Mohammadi-Nejad, Ali Reza, Stamatios N. Sotiropoulos, Auer, Dorothee P., Dewen Meng   +9 more
core   +1 more source

Monitoring Injected Drug Use in Greece Through Syringe Residue Analysis: A Multicity Study Within the ESCAPE Network

Drug Testing and Analysis, EarlyView.
A total of 2121 used syringes were analyzed in Athens, Thessaloniki, and Patras between 2022 and 2024. Distinct drug‐use patterns were observed across the three cities. Benzodiazepines, pregabalin, methadone, and fentanyl were increasingly detected in 2024.
Christina Matiaki, Anastasios Trakakis, Athanasios Theocharis, Chara Parpala, Chara Kotsailidou, Alexandros Psarianos, Emmanouil Chatzichristofis, Eleni Zagelidu, Panagiota Roussou, Nikolaos Raikos, Orthodoxia Mastrogianni   +10 more
wiley   +1 more source

Anticholinergic burden and frailty in older inpatients: insights from analysis of admission and discharge medicines using four anticholinergic scales

BMC Geriatrics
Background Exposure to high anticholinergic burden is associated with adverse outcomes in older adults. Older adults with frailty have greater vulnerability to adverse anticholinergic effects.
Mohammed Adem Mohammed, Amy Hai Yan Chan, Nasir Wabe, Ayesha Ali, Louis Harris, Sianne West, Rhea Colaabavala, Justine Aw, Jeff Harrison   +8 more
doaj   +1 more source

Anticholinergic burden in older inpatients on psychotropic medication: do we care?

, 2017
Objectives: This quality activity explored the prescribing patterns in an Older Persons Mental Health Inpatient Unit in order to establish whether the Anticholinergic Cognitive Burden Scale (ACB Scale) score on admission was reviewed to minimise ...
George, Manoj, Boris Zolotarev, Kisely, Steve, Jack Henderson, Warren, Andrew, Zolotarev, Boris, Manoj George, Henderson, Jack, Mei Shiang Lee, Lee, Mei Shiang, Steve Kisely, Andrew Warren   +11 more
core   +1 more source

Residual Limb Hyperhidrosis in Prosthetic Users: First Prospective Pilot of Topical Antiperspirant Treatment

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Residual limb hyperhidrosis (RLH) is a frequent and debilitating condition among lower‐limb prosthetic users. Although aluminium chloride is recommended first‐line for focal hyperhidrosis, its efficacy in RLH has not previously been evaluated in prospective studies.
Jette Schack, Kim Magnus Advocaat Sandberg Endre, Andrew Ritchie, Harald Steen   +3 more
wiley   +1 more source

Ischemic colitis induced by psychotropics drugs: a case report

European Psychiatry, 2022
Introduction Ischemic colitis (IC) is a rare condition due to hypoperfusion in the large intestine. Usually the etiology is unidentified, but many drugs are known to induce it because of their anticholinergic effects.
C. Alvarez Garcia, A. Sanz Giancola, L. Nocete Navarro   +2 more
doaj   +1 more source

Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough

The Laryngoscope, EarlyView.
The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen, Carmen Esna, Camille Prigent, Anna Miles   +3 more
wiley   +1 more source