Results 61 to 70 of about 40,585 (248)

Dose response relationship of cumulative anticholinergic exposure with incident dementia: validation study of Korean anticholinergic burden scale [PDF]

, 2020
Background The dose response relationship of nine-year cumulative anticholinergic exposure and dementia onset was investigated using the Korean version anticholinergic burden scale (KABS) in comparison with the Anticholinergic Cognitive ...
Suh, Yewon, Ju-Yeun Lee, Sunghee Hwang, Kyung Hee Choi, Choi, Kyung H, Young-Mi Ah, Kwanghee Jun, Hwang, Sunghee, Jun, Kwanghee, Lee, Ju-Yeun, Han, Euna, Euna Han, Ah, Young-Mi, Yewon Suh   +13 more
core   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal, Katherine A. Dudley, Stacey Sullivan, Kate T. Brizzi, Katherine M. Burke, Sydney Hall, Kiersten Pease, Joshua N. Goldstein, James D. Berry, Doreen T. Ho   +9 more
wiley   +1 more source

Save the Bladder: Continent Urinary Diversion as Best Practice for Patients With Refractory Neurogenic Lower Urinary Tract Dysfunction

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Refractory neurogenic lower urinary tract dysfunction presents an obstinate clinical problem. For patients who fail nonsurgical measures, we advocate for bladder‐sparing, continent urinary diversion as the optimal approach to management.
Brian W. Chao, Sean P. Elliott
wiley   +1 more source

Mirabegron in the Treatment of Overactive Bladder: Safety and Efficacy in the Very Elderly Patient

Clinical Interventions in Aging, 2020
Asad Makhani,1 Miriam Thake,2 William Gibson1 1University of Alberta, Division of Geriatric Medicine, Edmonton, Alberta, Canada; 2Great Western Hospitals NHS Foundation Trust, Swindon SN3 6BB, UKCorrespondence: William GibsonUniversity of Alberta ...
Makhani A, Thake M, Gibson W
doaj  

How Can We Personalize the Delivery of Onabotulinumtoxin‐A for Patients With Neurogenic Lower Urinary Tract Dysfunction?

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background & Aims Neurogenic lower urinary tract dysfunction (NLUTD) can produce bothersome urinary symptoms, impact quality of life, and in some cases, lead to deterioration of upper urinary tract function. Intradetrusor injection of onabotulinumtoxin‐A (BoNT‐A) is approved for NLUTD in patients who have an inadequate response to or ...
Shirley L. Wang, William I. Jaffe, Ariana L. Smith   +2 more
wiley   +1 more source

Antidiarrheal potential of Distemonanthus benthamianus Baillon. extracts via inhibiting voltage-dependent calcium channels and cholinergic receptors

Asian Pacific Journal of Tropical Biomedicine, 2019
Objective: To evaluate spasmolytic mechanisms of aqueous and methanolic extracts from Distemonanthus benthamianus trunk-bark. Methods: Spasmolytic activities of extracts were evaluated in vitro on spontaneous and potassium chloride-induced jejunum ...
William Yousseu Nana, Gilbert Ateufack, Marius Mbiantcha, Shamim Khan, Hafiz Majid Rasheed, Albert Atsamo, Abdul Jabbar Shah, Albert Kamanyi, Taous Khan   +8 more
doaj   +1 more source

Mirabegron and Intradetrusor Onabotulinumtoxina for Overactive Bladder in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective To synthesize the evidence on the efficacy and safety of mirabegron and intradetrusor onabotulinumtoxinA (BoNT‐A) as separate interventions for overactive bladder (OAB) in Parkinson's disease (PD). Methods A systematic review and meta‐analysis with parallel synthesis of two distinct interventions was conducted of randomized and ...
Hussain Arshad, Raiyana Nuha, Shehab Khashaba, David Gillatt, Simon J. G. Lewis   +4 more
wiley   +1 more source

Urodynamic Voiding Patterns in Multiple Sclerosis

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims This study aimed to describe urodynamic voiding patterns in patients with MS (PwMS) using standardized assessments, and to compare the performance of the available nomograms and indices for obstruction and bladder contractility. Methods PwMS and lower urinary tract symptoms underwent cystometry and pressure flow studies.
Camille Chesnel, Nicolas Turmel, Maelys Teng, Emilie Blouet, Gérard Amarenco, Claire Hentzen   +5 more
wiley   +1 more source

Mechanism-Informed Pharmacotherapy Optimization and Deprescribing: A Redox-Mitochondrial Framework. [PDF]

Pharmacol Res Perspect
From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Martinc B.
europepmc   +2 more sources

Assessing Patient Centered Urological Care for Spina Bifida: A Collaboration Between the European Association of Urology–European Society for Pediatric Urology (EAU−ESPU) Pediatric Urology Guidelines Panel and the International Federation for Spina Bifida and Hydrocephalus (IFSBH)

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction & Objectives People with spina bifida (SB) require lifelong care from various specialists, with the organization and availability of care differing across Europe. This variation likely impacts care outcomes from a patient perspective.
Lisette ‘t Hoen, Christian Radmayr, Michele Gnech, Carla Bezuidenhout, Allon van Uitert, Marco Castagnetti, Berk Burgu, Fardod O'Kelly, Josine Quaedackers, Yazan Rawashdeh, Selçuk Silay, Anna Bujons, Guy Bogaert, Niklas Pakkasjarvi, Martin Skott, Uchenna Kennedy, Beatriz Bañuelos Marco, Sylvia Roozen   +17 more
wiley   +1 more source