Results 1 to 10 of about 10,125 (112)

Anticholinergic Burden and Progression to Kidney Replacement Therapy [PDF]

Kidney International Reports
Introduction: The cholinergic system exerts nephroprotective effects through antiinflammatory and vasoregulatory pathways. However, the impact of anticholinergic medications on chronic kidney disease (CKD) progression remains unexplored. This study aimed
Agathe Mouheb, Ziad A. Massy, Marie Metzger, Hélène Levassort, Marion Pépin, Maurice Laville, Natalia Alencar de Pinho, Solène M. Laville, Sophie Liabeuf, Natalia Alencar de Pinho, Dorothée Cannet, Christian Combe, Denis Fouque, Luc Frimat, Aghilès Hamroun, Yves-Edouard Herpe, Christian Jacquelinet, Oriane Lambert, Céline Lange, Maurice Laville, Sophie Liabeuf, Ziad A. Massy, Marie Metzger, Pascal Morel, Christophe Pascal, Roberto Pecoits-Filho, Joost Schantsra, Bénédicte Stengel, Professor T. Hannedouche, B. Moulin, Dr A. Klein, Professor C. Combe, Dr J.P. Bourdenx, Dr A. Keller, Dr C. Delclaux, Dr B. Vendrely, Dr B. Deroure, Dr A. Lacraz, Dr T. Lobbedez, Dr I. Landru, Professor Z. Massy, Professor P. Lang, Dr X. Belenfant, Professor E. Thervet, Dr P. Urena, Dr M. Delahousse, Dr C. Vela, Professor M. Essig, Dr D. Clément, Dr H. Sekhri, Dr M. Smati, Dr M. Jamali, Dr B. Hacq, Dr V. Panescu, Dr M. Bellou, Professor Luc Frimat, Professor N. Kamar, Professor C. Noël, Professor F. Glowacki, Dr N. Maisonneuve, Dr R. Azar, Dr M. Hoffmann, Professor M. Hourmant, Dr A. Testa, Dr D. Besnier, Professor G. Choukroun, Dr G. Lambrey, Professor S. Burtey, Dr G. Lebrun, Dr E. Magnant, Professor M. Laville, Professor D. Fouque, L. Juillard, Dr C. Chazot, Professor P. Zaoui, Dr F. Kuentz   +75 more
doaj   +2 more sources

Anticholinergic burden in community-dwelling older adults: prevalence, associated factors, and agreement between measurement scales [PDF]

Frontiers in Pharmacology
AimAssessing cumulative anticholinergic exposure is essential in geriatric pharmacotherapy and medication safety. The present study aimed to provide real-world evidence on this issue in community-dwelling older adults.
Francisco De Borja Rodríguez-Salas, María Angeles Merchán-Cruz, Ricardo Ocaña-Riola, Pilar María Díez-de-Baldeón-Chicón, José Pablo Lara, José Pablo Lara, Encarnación Blanco-Reina, Encarnación Blanco-Reina   +7 more
doaj   +2 more sources

Duration of anticholinergic burden and polypharmacy and the risk of fractures in older Korean adults: a nationwide cohort study [PDF]

BMC Geriatrics
Background Older adults are at elevated risk of fractures and frequently use multiple medications. Evidence on the association between fracture risk, medication use duration, and anticholinergic burden remains limited.
Youn Huh, Ki Young Son
doaj   +2 more sources

Impact of the Anticholinergic Burden on Disease-Specific Symptoms in Parkinsonian Syndromes

Brain Sciences
Background: Anticholinergic adverse effects pose a relevant threat to patients, in particular elderly and cognitively impaired patients. Patients with Parkinsonian syndromes are especially at risk from anticholinergic adverse effects due to the often ...
Günter U Höglinger, Martin Klietz, Johannes Heck   +2 more
exaly   +3 more sources

Polypharmacy, anticholinergic burden and oral microbiome among U.S. middle-aged and older adults: a representative national survey [PDF]

Journal of Oral Microbiology
Objectives Polypharmacy has been linked to alterations in gut microbiota, but its effects on the oral microbiome remain underexplored. This study aimed to examine the association of polypharmacy and anticholinergic burden with oral microbiome diversity ...
Kai Wei, Yanping Yang, Chun Chen, Yong Yang, Kui Hu, Qi Chen   +5 more
doaj   +2 more sources

Anticholinergic Burden in Elderly People in Nursing Homes: Cross-Sectional Assessment Using ACB Calculator and CRIDECO Anticholinergic Load Scale [PDF]

Medicines
Background/Objectives: Anticholinergic burden is an important risk marker in older adults, associated with cognitive decline, falls, and increased mortality. This study aimed to assess anticholinergic burden in institutionalized elderly individuals using
Tânia Nascimento, Maria Ana Matos, Ezequiel Pinto   +2 more
doaj   +2 more sources

Development of the Swedish anticholinergic burden scale (Swe-ABS)

BMC Geriatrics, 2023
Background Drugs with anticholinergic properties are associated with cognitive adverse effects, especially in patients vulnerable to central muscarinic antagonism. A variety of drugs show weak, moderate or strong anticholinergic effects.
Tanja Rube, Astrid Ecorcheville, Elisabet Londos, Sara Modig, Per Johansson   +4 more
doaj   +1 more source

Anticholinergic Medication Burden in Parkinson’s Disease Outpatients

Journal of Parkinson’s Disease, 2022
Background: Individuals with Parkinson’s disease (PD) may be especially vulnerable to future cognitive decline from anticholinergic medications. Objective: To characterize anticholinergic medication burden, determine the co-occurrence of anticholinergic ...
Huma Nawaz, Lana Sargent, Helengrace Quilon, Leslie J. Cloud, Claudia M. Testa, Jon D. Snider, Sarah K. Lageman, Mark S. Baron, Brian D. Berman, Kristin Zimmerman, Elvin T. Price, Nitai D. Mukhopadhyay, Matthew J. Barrett   +12 more
doaj   +1 more source

A meta-analysis of observational studies on anticholinergic burden and fracture risk: evaluation of conventional burden scales

Journal of Pharmaceutical Health Care and Sciences, 2021
Background Anticholinergic burden potentially increases the risk of fracture. Although there are various anticholinergic burden scales, little is known about the inter-scale compatibility regarding the relationship of anticholinergic burden with fracture
Yukari Ogawa, Toshinori Hirai, Kiyoshi Mihara   +2 more
doaj   +1 more source

Anti-Cholinergic Drug Burden Among Ambulatory Elderly Patients in a Nigerian Tertiary Healthcare Facility

Frontiers in Pharmacology, 2021
Background: The use of drugs with anticholinergic effects among elderly patients is associated with adverse clinical outcomes. There is paucity of information about anticholinergic drug burden among Nigerian elderly population.Objectives: To determine ...
Joseph O. Fadare, Joseph O. Fadare, Abimbola Margaret Obimakinde, Abimbola Margaret Obimakinde, Felix O. Aina, Ebisola J. Araromi, Theophilus Adekunle Adegbuyi, Oluwatoba E. Osasona, Tosin A. Agbesanwa   +8 more
doaj   +1 more source