The past, present and future of anticholinergic drugs [PDF]
Therapeutic Advances in Psychopharmacology, 2023 In current medical practice, it is difficult to find any reports claiming that drugs that are primarily anticholinergic or those that have significant anticholinergic effects have any therapeutic benefits.
David Healy
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The role of sex, age and genetic polymorphisms of CYP enzymes on the pharmacokinetics of anticholinergic drugs [PDF]
Pharmacology Research & Perspectives, 2021 There is evidence that use of drugs with anticholinergic properties increases the risk of cognitive impairment, and increased exposure to these drugs potentiates this risk.
Shanna C. Trenaman +3 more
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Prescription of Anticholinergic Drugs in Patients With Schizophrenia: Analysis of Antipsychotic Prescription Patterns and Hospital Characteristics [PDF]
Frontiers in Psychiatry, 2022 In several clinical guidelines for schizophrenia, long-term use of anticholinergic drugs is not recommended. We investigated the characteristics of the use of anticholinergics in patients with schizophrenia by considering psychotropic prescription ...
Hikaru Hori +43 more
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Anticholinergic Drugs Interact With Neuroprotective Chaperone L-PGDS and Modulate Cytotoxicity of Aβ Amyloids [PDF]
Frontiers in Pharmacology, 2020 Anticholinergic drugs can be used as a treatment for many diseases. However, anticholinergic drugs are also known for their cognition-related side effects. Recently, there has been an increasing number of reports indicating a positive association between
Kimberly Jia Yi Low +2 more
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Anticholinergic Drugs in Geriatric Psychopharmacology [PDF]
Frontiers in Neuroscience, 2019 Drugs with anticholinergic action are widely prescribed in the elderly population due to their potential clinical benefits. However, these benefits are limited by adverse effects which may be serious in particular circumstances.
Jorge López-Álvarez +7 more
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Risk of dementia associated with anticholinergic drugs for overactive bladder in adults aged ≥55 years: nested case-control study [PDF]
BMJ MedicineObjective To investigate whether different anticholinergic drug treatments for overactive bladder have differential risks for incident dementia, in a large representative population of older adults in England.Design Nested case-control study.Setting ...
Tom Dening +7 more
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The Prevalence of Anticholinergic Drugs and Correlation with Pneumonia in Elderly Patients: A Population-Based Study in Taiwan [PDF]
International Journal of Environmental Research and Public Health, 2020 Chien-Ying Lee +2 more
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Anticholinergic drugs and oral health-related quality of life in patients with schizophrenia: a pilot study [PDF]
Translational Neuroscience, 2020 Frédéric Denis, RUDE Nathalie
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Development of the Swedish anticholinergic burden scale (Swe-ABS)
BMC Geriatrics, 2023 Background Drugs with anticholinergic properties are associated with cognitive adverse effects, especially in patients vulnerable to central muscarinic antagonism. A variety of drugs show weak, moderate or strong anticholinergic effects.
Tanja Rube +4 more
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Frontiers in Pharmacology, 2021 Background: The use of drugs with anticholinergic effects among elderly patients is associated with adverse clinical outcomes. There is paucity of information about anticholinergic drug burden among Nigerian elderly population.Objectives: To determine ...
Joseph O. Fadare +8 more
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