Results 31 to 40 of about 1,055,250 (236)

Association between anticholinergic burden and dementia in UK Biobank

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
Background Previous studies on the relationship between anticholinergic drugs and dementia have reported heterogeneous results. This variability could be due to different anticholinergic scales and differential effects of distinct classes of drugs ...
Jure Mur, Tom C. Russ, Simon R. Cox, Riccardo E. Marioni, Graciela Muniz‐Terrera   +4 more
doaj   +1 more source

Delirium due to Anticholinergic Intoxication and Use of Physostigmine in Pediatric Emergency Room

, 2022
Anticholinergics are substances that antagonize the activity of the neurotransmitter acetylcholine. Anticholinergic syndrome (AS) occurs following a suicidal overdose, accidental drug intake, drug incompatibilities, and intake of multiple drugs ...
Alper Çiçek, Gülşah Demir, Tuğçe Nalbant, Pelin Elibol, Oğuz Demiroğlu, Gamze Gökalp, Şefika Bardak, Emel Berksoy   +7 more
core   +1 more source

Anticholinergic burden and cognitive function in a large German cohort of hospitalized geriatric patients.

PLoS ONE, 2017
PurposePrevious studies suggest an association between use of anticholinergic drugs in elderly patients and cognitive impairment. However, there are still limited data on the association of anticholinergic drug use and cognitive impairment as well as ...
Barbara Pfistermeister, Thomas Tümena, Karl-Günter Gaßmann, Renke Maas, Martin F Fromm   +4 more
doaj   +1 more source

Anti-cholinergic drug burden in patients with dementia increases after hospital admission: a multicentre cross-sectional study

BMC Geriatrics, 2022
Background Anticholinergic medications are drugs that block cholinergic transmission, either as their primary therapeutic action or as a secondary effect.
Annabelle Hook, Jessica L. Randall, Carla M. Grubb, Natalie Ellis, Jack Wellington, Aayushi Hemmad, Agisilaos Zerdelis, Andrew R. D. Winnett, Benjamin D. W. Geers, Bethany Sykes, Charlotte N. Auty, Cecilia Vinchenzo, Christiane E. Thorburn, Daniella Asogbon, Emily Granger, Heather Boagey, Juliet Raphael, Kajal Patel, Kartik Bhargava, Mary-Kate M. Dolley, Matthew J. Maden, Mehdin M. Shah, Qao M. Lee, Ratnaraj Vaidya, Simran Sehdev, Sneha Barai, Sophie Roche, Uzair Khalid, David A. Codling, Judith R. Harrison   +29 more
doaj   +1 more source

The Anticholinergic Drug Effect on Decreasing Cognitive in Geriatric Patients at Kota Surakarta General Hospital

Jurnal Manajemen dan Pelayanan Farmasi, 2018
This leads the geriatric patients to receive multiple drugs regimen (polypharmacy) which include using anticholinergic drugs. Risk of anticholinergics drug use is associated with cognitive impairments that have been demonstrated in experimental and ...
Nurlena Ikawati, Fita Rahmawati
doaj   +1 more source

Comparison of Beers Criteria^® anticholinergic drugs and other drugs.

, 2021
These box plots show the distribution of the lnROR by the anticholinergic drugs and the other drugs. (a) FAERS and (b) JADER.
Junko Nagai (11785635), Yoichi Ishikawa (480629)   +1 more
core   +1 more source

Development of a Brazilian anticholinergic activity drug scale

Einstein (São Paulo)
Objective To develop a scale of anticholinergic activity drugs used in Brazil, to be applied in health care and pharmacoepidemiology research. Methods We performed a literature review on PubMed/MEDLINE® to identify previously published scales of ...
Raiany Thaimeny Nery, Adriano Max Moreira Reis   +1 more
doaj   +1 more source

Assessment and comparison of anticholinergic exposure in older adults at a Basic Health Unit in Porto Alegre

Geriatrics, Gerontology and Aging, 2023
Objectives: To estimate the anticholinergic burden in geriatric patients using two scales and to assess the degree of agreement between them. Methods: Data from an observational study conducted in a primary health care service were used.
Tatiana da Silva Sempé, Taiane Santos Garcia, Isabela Heineck   +2 more
doaj   +1 more source

Anticholinergic drugs and physical function among frail elderly population

, 2007
Increasing evidence from experimental studies and human observations suggests that drugs with anticholinergic properties can cause physical and mental impairment.
R. Bernabei, G. Onder, C. Barillaro, M. Pahor, R. Liperoti, A. Russo, M. Cesari, F. Landi   +7 more
core   +1 more source

Dementia patients have greater anti-cholinergic drug burden on discharge from hospital: A multicentre cross-sectional study

European Psychiatry, 2021
Introduction Anticholinergic medications block cholinergic transmission. The central effects of anticholinergic drugs can be particularly marked in patients with dementia.
J. Randall, A. Hook, C-M. Grubb, N. Ellis, J. Wellington, A. Hemmad, A. Zerdelis, B. Geers, B. Sykes, C. Auty, C. Vinchenzo, C. Thorburn, D. Asogbon, E. Granger, H. Boagey, J. Raphael, K. Patel, K. Bhargava, M.-K. Dolley, M. Maden, M. Shah, Q. Lee, R. Vaidya, S. Sehdev, S. Barai, S. Roche, U. Khalid, J. Harrison, D. Codling   +28 more
doaj   +1 more source