Results 41 to 50 of about 1,055,250 (236)

Characterization of Anticholinergic Medication Use and Its Associations With Everyday Memory Problems and Cognitive Decline in Autistic Adults With Higher Support Needs

Autism Research, EarlyView.
ABSTRACT Among older adults in the general population, medications with anticholinergic (AC) effects are associated with declines in cognitive functioning and with dementia and Alzheimer's disease. Autistic people have high rates of co‐occurring medical conditions and polypharmacy across the lifespan; thus, they may be at particularly high risk of ...
Goldie A. McQuaid, Nancy Raitano Lee, Gregory L. Wallace   +2 more
wiley   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Anticholinergic Drug Exposure Increases the Risk of Delirium in Older Patients Undergoing Elective Surgery

Frontiers in Medicine, 2022
IntroductionPostoperative delirium (POD) is a common and serious adverse event of surgery in older people. Because of its great impact on patients' safety and quality of life, identification of modifiable risk factors could be useful.
Matthias L. Herrmann, Matthias L. Herrmann, Cindy Boden, Christoph Maurer, Christoph Maurer, Felix Kentischer, Eva Mennig, Sören Wagner, Sören Wagner, Lars O. Conzelmann, Bernd R. Förstner, Michael A. Rapp, Christine A. F. von Arnim, Michael Denkinger, Michael Denkinger, Gerhard W. Eschweiler, Christine Thomas, Christine Thomas   +17 more
doaj   +1 more source

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Investigation of the total anticholinergic load of reported anticholinergic drug-related adverse events using the Japanese adverse drug event report database: a retrospective pharmacovigilance study

Journal of Pharmaceutical Health Care and Sciences
Background The Anticholinergic Risk Scale and Total Anticholinergic Load were developed to assess the risks associated with anticholinergic drugs. Recently, the Japan Anticholinergic Risk Scale was introduced; however, the total anticholinergic load for ...
Yusuke Kan, Maki Doi, Yoshihiro Uesawa
doaj   +1 more source

Sex Differences in Prescribing Patterns of Anticholinergics and β3-Adrenoceptor Agonists for Overactive Bladder: A Nationwide Study in Japan, FY2017-FY2024. [PDF]

Low Urin Tract Symptoms
ABSTRACT Objectives Drug treatment for overactive bladder (OAB) is changing, with an increasing share of β3‐adrenoceptor agonists relative to anticholinergics, but it is not known how far this change has progressed in older people, who are most vulnerable to the risks of anticholinergics.
Koike T, Kawahara T, Hashizume A, Yamazaki M, Takamoto D, Ito H, Takeshima T, Uemura H, Makiyama K, Teranishi JI.   +9 more
europepmc   +2 more sources

Antidepressant Misuse in Esports: A Review of Pharmacology, Adverse Effects, Pharmacokinetics and Biomatrix‐Based Detection for Anti‐Doping Applications

Drug Testing and Analysis, EarlyView.
This review highlights the misuse of antidepressants as potential cognitive‐enhancing agents in Esports. Despite pharmacological effects that overlap with those of psychostimulants, antidepressants remain an under‐recognised source of doping in Esports.
Kassim Ali Salum, Shao‐Hsin Hung, Meng‐Tsang Hsieh, Mei‐Chich Hsu, William Chih‐Wei Chang   +4 more
wiley   +1 more source

The association between polypharmacy, anticholinergic burden, comorbidities, and hospital length of stay in geriatric patients

Medicine Science, 2023
We aimed to evaluate the association between polypharmacy, anticholinergic burden, comorbidities, and hospital length of stay in older adults. We analyzed 213 older in-patient data retrospectively.
Gulru Ulugerger Avci, Bahar Bektan Kanat, Gunay Can, Hakan Yavuzer, Deniz Suna Erdincler, Alper Doventas   +5 more
doaj   +1 more source

Anticholinergic Drugs in Dogs [PDF]

, 2014
Can I use anticholinergic drugs with dexmedetomidine in dogs?This article is published as Hay Kraus BL. Anti-cholinergic Drugs in Dogs. Vet Pulse, Iowa State University College of Veterinary Medicine. Vol. 1, Number 3. September 2014.
Hay Kraus, Bonnie
core  

Anticholinergic therapy for acute asthma in children. [PDF]

, 2012
Inhaled anticholinergics as single agent bronchodilators (or in combination with beta(2)-agonists) are one of the several medications available for the treatment of acute asthma in ...
Acworth, Jason P., Teoh, Laurel, Acworth, JP, van Asperen, P, Cates, Christopher J., Chang, Anne B., Hurwitz, Mark, Hurwitz, M, Chang, AB, Teoh, L, Cates, CJ, van Asperen, Peter, Chang, A. B., Van Asperen, Peter P., Cates, Christopher J, Acworth, Jason P, Chang, Anne B   +16 more
core   +1 more source