Results 41 to 50 of about 715,175 (219)

Anti-cholinergic drug burden in patients with dementia increases after hospital admission: a multicentre cross-sectional study

BMC Geriatrics, 2022
Background Anticholinergic medications are drugs that block cholinergic transmission, either as their primary therapeutic action or as a secondary effect.
Annabelle Hook, Jessica L. Randall, Carla M. Grubb, Natalie Ellis, Jack Wellington, Aayushi Hemmad, Agisilaos Zerdelis, Andrew R. D. Winnett, Benjamin D. W. Geers, Bethany Sykes, Charlotte N. Auty, Cecilia Vinchenzo, Christiane E. Thorburn, Daniella Asogbon, Emily Granger, Heather Boagey, Juliet Raphael, Kajal Patel, Kartik Bhargava, Mary-Kate M. Dolley, Matthew J. Maden, Mehdin M. Shah, Qao M. Lee, Ratnaraj Vaidya, Simran Sehdev, Sneha Barai, Sophie Roche, Uzair Khalid, David A. Codling, Judith R. Harrison   +29 more
doaj   +1 more source

Anticholinergic Burden: A Bibliometric Analysis of Research Trends

Trends in Pharmacy
Background: Anticholinergic burden is linked to adverse outcomes, including mortality, cardiovascular events, falls, cognitive decline, and dementia, particularly in middle- to older-aged populations.
Betül Sümbül-Şekerci, Özge Pasin, Halil Aziz Velioğlu   +2 more
doaj   +5 more sources

Are Anticholinergic Symptoms a Risk Factor for Falls in Older General Practice Patients With Polypharmacy? Study Protocol for the Development and Validation of a Prognostic Model

Frontiers in Pharmacology, 2021
Background: Cumulative anticholinergic exposure, also known as anticholinergic burden, is associated with a variety of adverse outcomes. However, studies show that anticholinergic effects tend to be underestimated by prescribers, and anticholinergics are
Truc Sophia Dinh, Ana Isabel González-González, Ana Isabel González-González, Andreas D. Meid, Kym I. E. Snell, Henrik Rudolf, Maria-Sophie Brueckle, Jeanet W. Blom, Ulrich Thiem, Ulrich Thiem, Hans-Joachim Trampisch, Petra J. M. Elders, Norbert Donner-Banzhoff, Ferdinand M. Gerlach, Sebastian Harder, Marjan van den Akker, Paul P. Glasziou, Walter E. Haefeli, Christiane Muth, Christiane Muth   +19 more
doaj   +1 more source

Anticholinergic burden in older inpatients on psychotropic medication: do we care?

, 2017
Objectives: This quality activity explored the prescribing patterns in an Older Persons Mental Health Inpatient Unit in order to establish whether the Anticholinergic Cognitive Burden Scale (ACB Scale) score on admission was reviewed to minimise ...
George, Manoj, Boris Zolotarev, Kisely, Steve, Jack Henderson, Warren, Andrew, Zolotarev, Boris, Manoj George, Henderson, Jack, Mei Shiang Lee, Lee, Mei Shiang, Steve Kisely, Andrew Warren   +11 more
core   +1 more source

Characterization of Anticholinergic Medication Use and Its Associations With Everyday Memory Problems and Cognitive Decline in Autistic Adults With Higher Support Needs

Autism Research, EarlyView.
ABSTRACT Among older adults in the general population, medications with anticholinergic (AC) effects are associated with declines in cognitive functioning and with dementia and Alzheimer's disease. Autistic people have high rates of co‐occurring medical conditions and polypharmacy across the lifespan; thus, they may be at particularly high risk of ...
Goldie A. McQuaid, Nancy Raitano Lee, Gregory L. Wallace   +2 more
wiley   +1 more source

Anticholinergic Medication and Caries Status Predict Xerostomia under 65

Dentistry Journal, 2023
The use of anticholinergic medications is increasing in younger ages, yet information about xerostomia, the most common anticholinergic side effect, is limited.
Hui Ling Cheah, Michael Gray, Shahenda Aboelmagd, Abdul Basir Barmak, Szilvia Arany   +4 more
doaj   +1 more source

Comentarios sobre la herramienta web Anticholinergic Burden Calculator. RÉPLICA

, 2019
Comment about Anticholinergic Drug Scale (ADS)
Villalba Moreno, Ángela, Santos-Ramos, Bernardo, Sánchez Fidalgo, Susana, Alfaro Lara, Eva Rocío   +3 more
core   +1 more source

Anticholinergic burden and frailty in older inpatients: insights from analysis of admission and discharge medicines using four anticholinergic scales

BMC Geriatrics
Background Exposure to high anticholinergic burden is associated with adverse outcomes in older adults. Older adults with frailty have greater vulnerability to adverse anticholinergic effects.
Mohammed Adem Mohammed, Amy Hai Yan Chan, Nasir Wabe, Ayesha Ali, Louis Harris, Sianne West, Rhea Colaabavala, Justine Aw, Jeff Harrison   +8 more
doaj   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Anticholinergic Medication Burden–Associated Cognitive Impairment in Schizophrenia [PDF]

, 2021
OBJECTIVE: Many psychotropic medications used to treat schizophrenia have significant anticholinergic properties, which are linked to cognitive impairment and dementia risk in healthy subjects.
Radant, Allen D., Tsuang, Debby W., Braff, David L, Lazzeroni, Laura C, MacDonald, Laura R, MacDonald, Laura R., Light, Gregory A, Sugar, Catherine A., Gur, Raquel E, Molina, Juan L, Greenwood, Tiffany A., Lazzeroni, Laura C., Molina, Juan L., Green, Michael F, Nuechterlein, Keith H., Joshi, Yash B., Greenwood, Tiffany A, Silverman, Jeremy M., Swerdlow, Neal R., Nungaray, John A, Turetsky, Bruce I., Light, Gregory A., Gur, Ruben C., Stone, William S., Nungaray, John A., Green, Michael F., Thomas, Michael L, Thomas, Michael L., Nuechterlein, Keith H, Sprock, Joyce, Tsuang, Ming T, Radant, Allen D, Gur, Ruben C, Joshi, Yash B, Gur, Raquel E., Swerdlow, Neal R, Tsuang, Debby W, Silverman, Jeremy M, Turetsky, Bruce I, Tsuang, Ming T., Sugar, Catherine A, Stone, William S, Braff, David L.   +42 more
core   +1 more source