Association of Anticholinergic Burden with Cognitive and Functional Status in a Cohort of Hospitalized Elderly: Comparison of the Anticholinergic Cognitive Burden Scale and Anticholinergic Risk Scale [PDF]
Drugs & Aging, 2013 Abstract Background Drugs with anticholinergic effects are associated with adverse events such as delirium and falls as well as cognitive decline and loss of independence. Objective The aim of the study was to evaluate the association between anticholinergic burden and both cognitive and functional status, according to the hypothesis that the ...
Pasina, L +12 more
core +6 more sources
Pharmacogenetic associations of CYP2D6 and CYP2C19 variants with anticholinergic drug burden and hyposalivation [PDF]
Frontiers in PharmacologyIntroductionAnticholinergic medications frequently cause hyposalivation (decreased saliva flow) through parasympathetic inhibition. This adverse effect is related to anticholinergic burden, reflecting the cumulative exposure to drugs with anticholinergic
Olga A. Korczeniewska +5 more
doaj +2 more sources
Anticholinergic burden and most common anticholinergic-acting medicines in older general practice patients [PDF]
Slovenian Journal of Public Health, 2018 Abstract Introduction Anticholinergic burden in older adults has been correlated with cognitive decline, delirium, dizziness and confusion, falls and hospitalisations. Nevertheless, anticholinergic-acting medications remain commonly prescribed in up to a third of older adults in primary care ...
Gorup Eva +2 more
openaire +4 more sources
Anticholinergic Burden and Dry Mouth in Middle-Aged People [PDF]
JDR Clinical & Translational Research, 2019 Introduction: Anticholinergic burden refers to the cumulative effect of taking 1 or more drugs with anticholinergic properties. At the moment, little is known about the association between the anticholinergic burden and dry mouth. Objectives:
Syrjälä Anna-Maija +5 more
openaire +5 more sources
Anticholinergic burden and bone health in rheumatoid arthritis. [PDF]
Rev Assoc Med Bras (1992)SUMMARY OBJECTIVE: Rheumatoid arthritis is associated with osteoporosis and falls. While anticholinergic burden increases fracture risk in older adults, its contribution to bone health in rheumatoid arthritis is unclear.
Uysal B, Salbaş E, Şahin N.
europepmc +2 more sources
ANTICHOLINERGIC BURDEN IN DEMENTIA
Dementia & Neuropsychologia, 2021 Background: The anticholinergic burden is associated with a greater risk of functional/ cognitive decline and morbidity/mortality. Objectives: Our aim was to quantify the anticholinergic burden in the first visit in our dementia tertiary outpatient clinic.
Carolina Rodrigue Formoso +4 more
openaire +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Comparative associations between anticholinergic burden and emergency department visits for anticholinergic adverse events in older Korean adults: a nested case-control study using national claims data for validation of a novel country-specific scale [PDF]
, 2021 Background Considering the limited generalizability of previous anticholinergic burden scales, the Korean Anticholinergic Burden Scale (KABS) as a scale specific to the Korean population was developed.
Hwang, Sunghee +5 more
core +1 more source
The effect of medication reviews on reducing medication anticholinergic burden in elderly patients [PDF]
, 2017 Anticholinergic side effects of medications often misdiagnosed as cognitive function decline in the elderly. The study aims to explore the effectiveness of home medication reviews on reducing anticholinergic burden caused by medications with ...
Morrissey, Hana +2 more
core +3 more sources
The anticholinergic burden: from research to practice
Australian Prescriber, 2022 Drugs with anticholinergic effects are known to cause adverse effects such as dry mouth, constipation and urinary retention. In older people drugs with anticholinergic effects may contribute to cognitive decline and a loss of functional capacity. Many drugs that are not in the anticholinergic drug class also have anticholinergic effects.
Hilmer, Sarah N, Gnjidic, Danijela
openaire +2 more sources