Results 101 to 110 of about 83,224 (354)

Heroin Adulterated with the Novel Synthetic Cannabinoid, 5F-MDMB-PINACA: A Case Series [PDF]

open access: yes, 2020
Introduction: Heroin can be adulterated with various substances that may or may not have pharmacological effects. Here we report a case series of 8 patients who presented to the emergency department after overdose with intravenous heroin preparation ...
Arnold, Ryan   +5 more
core  

Serum methylarginines and spirometry-measured lung function in older adults [PDF]

open access: yes, 2013
Rationale: Methylarginines are endogenous nitric oxide synthase inhibitors that have been implicated in animal models of lung disease but have not previously been examined for their association with spirometric measures of lung function in humans ...
A Koarai   +47 more
core   +5 more sources

Anticholinergic Drugs in Geriatric Psychopharmacology

open access: yesFrontiers in Neuroscience, 2019
Drugs with anticholinergic action are widely prescribed in the elderly population due to their potential clinical benefits. However, these benefits are limited by adverse effects which may be serious in particular circumstances.
J. López-Álvarez   +2 more
semanticscholar   +1 more source

Long‐Term Cost Utility Analysis of Endoscopic Sinus Surgery: Analysis of 5‐Year Outcomes

open access: yesThe Laryngoscope, EarlyView.
This study utilizes a cohort‐style Markov decision tree economic model to evaluate the long‐term (5‐year) cost‐effectiveness of endoscopic sinus surgery versus medical management for patients with chronic rhinosinusitis. The results show that the endoscopic sinus surgery strategy cost more ($63,296.27) but yielded increased quality‐adjusted life years (
Dara R. Adams   +5 more
wiley   +1 more source

Managing Dystonia in Partington Syndrome

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Bilateral focal hand dystonia is an almost pathognomonic sign of Partington syndrome, frequently accompanied by intellectual disability and oromotor dyspraxia. However, a few studies have focused on the treatment of this focal dystonia, making patient management uncertain.
Emilie Pichon   +13 more
wiley   +1 more source

Anticholinergic medication use and falls in postmenopausal women: Findings from the women's health initiative cohort study [PDF]

open access: yes, 2016
Background: Results from studies assessing the association between anticholinergic use and falls are mixed, and prior studies are limited in their ability to control for important potential confounders.
Bea, JW   +7 more
core   +3 more sources

Anticholinergic Burden and Botulinum Toxin Needs after Deep Brain Stimulation in Adult and Pediatric Patients with Dystonia

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Anticholinergic medications and botulinum neurotoxin injections are established treatments for dystonia, yet they carry potential side effects and practical challenges. Deep brain stimulation (DBS) is offered in case of poor response to these approaches.
Marcela A. Montiel   +5 more
wiley   +1 more source

Mirabegron in the Treatment of Overactive Bladder: Safety and Efficacy in the Very Elderly Patient

open access: yesClinical Interventions in Aging, 2020
Asad Makhani,1 Miriam Thake,2 William Gibson1 1University of Alberta, Division of Geriatric Medicine, Edmonton, Alberta, Canada; 2Great Western Hospitals NHS Foundation Trust, Swindon SN3 6BB, UKCorrespondence: William GibsonUniversity of Alberta ...
Makhani A, Thake M, Gibson W
doaj  

Antidiarrheal potential of Distemonanthus benthamianus Baillon. extracts via inhibiting voltage-dependent calcium channels and cholinergic receptors

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2019
Objective: To evaluate spasmolytic mechanisms of aqueous and methanolic extracts from Distemonanthus benthamianus trunk-bark. Methods: Spasmolytic activities of extracts were evaluated in vitro on spontaneous and potassium chloride-induced jejunum ...
William Yousseu Nana   +8 more
doaj   +1 more source

Are Anticholinergic Medications Associated With Increased Risk of Dementia and Behavioral and Psychological Symptoms of Dementia? A Nationwide 15-Year Follow-Up Cohort Study in Taiwan

open access: yesFrontiers in Pharmacology, 2020
Background/ObjectiveIn previous reports, the usage of anticholinergic medications has been associated with an increased risk of dementia with prolonged usage or with a high Anticholinergic Cognitive Burden (ACB).
Yia-Ping Liu   +14 more
doaj   +1 more source

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