Results 91 to 100 of about 40,585 (248)
Anticholinergic Impact On Cognition In Schizophrenia [PDF]
, 2012 This secondary analysis examined the relationship between the total anticholinergic load and scores on cognitive tests in 94 patients diagnosed with schizophrenia or schizoaffective disorder.
Underwood, Catherine
core +1 more source
, 2015 Background: The cumulative effect of taking multiple medicines with anticholinergic properties termed as anticholinergic burden can adversely impact cognition, physical function and increase the risk of mortality. Expert opinion derived risk scales are
Nishtala, PS (15593765) +2 more
core
Symptom‐guided reduction of BCG dwell time: findings from the north‐REG randomized trial
BJU International, EarlyView.Objectives To evaluate the impact of personalized dwell‐time (DT) reductions on symptom prevalence and systemic toxicities in patients undergoing Bacillus Calmette–Guérin (BCG) instillation for non‐muscle invasive bladder cancer (NMIBC). Methods Within a multinational randomized controlled trial (North‐REG Dwell Time Study [NCT04701151]), 225 patients ...
Lene Munk +15 more
wiley +1 more source
The use of anticholinergic antiparkinson agents in Norway: Epidemiology, toxicology and clinical implications [PDF]
, 2010 This thesis is based on two fundamental questions: Which patients are currently using anticholinergic antiparkinson drugs? Does it matter which anticholinergic antiparkinson drug they are using?
Gjerden, Pål
core +1 more source
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Phloroglucinol inhibits human ureteral contractions via activation of cAMP‐PKA pathway
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Phloroglucinol is used to treat renal colic, especially when non‐steroidal anti‐inflammatory drugs are contraindicated. This study aimed to clarify its mechanism by examining effects on human ureteral contractility and underlying signalling pathways. Experimental Approach Urinary levels of neurokinin A (NKA), substance P
Hanwen Liu +12 more
wiley +1 more source
Examination and Estimation of Anticholinergic Burden
, 2016 Medicines with anticholinergic activity are widely prescribed for the older population aged ≥ 65 years for various medical conditions. A current estimate is that one-third to more than one-half of commonly prescribed medicines for older people have ...
Salahudeen, Mohammed Saji
core
, 2018 Anticholinergic burden in older adults has been correlated with cognitive decline, delirium, dizziness and confusion, falls and hospitalisations. Nevertheless, anticholinergic-acting medications remain commonly prescribed in up to a third of older adults
Petek šter Marija +2 more
core +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background and objectives Primary axillary hyperhidrosis (PAHH) results from dysregulation of the autonomic nervous system and typically begins during puberty. Treatment options for adolescents remain limited. This open‐label phase II study evaluated the safety, local tolerability, systemic exposure, and efficacy of 1% GPB cream over 8 weeks in
Rolf‐Markus Szeimies +8 more
wiley +1 more source
Journal of Medicinal Plants, 2010 Background: Barberry (Berberris vulgaris) is a well known medicinal plant in Iran and has also been used as food. Objective: This study was conducted to evaluate antihistaminic and anticholinergic activity of methanolic extract of barberry fruit. Methods:
R Khosrokhavar, A Ahmadiani, F Shamsa
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