Results 101 to 110 of about 354,756 (297)
Intracerebral hematomas during anticoagulant treatment. [PDF]
C L Franke +4 more
openalex +1 more source
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun +8 more
wiley +1 more source
Prevention of Hemorrhagic Complications After Dental Extractions Into Open Heart Surgery Patients Under Anticoagulant Therapy: The Use of Leukocyte- and Platelet-Rich Fibrin [PDF]
Gilberto Sammartino +4 more
openalex +1 more source
Virucidal polymers serve as effective antivirals by not only inhibiting viruses but also destroying them. Inspired by the chemical properties of mucin‐mimetics, dendronized polyglycerol‐sulfated, mucin‐inspired amphiphilic copolymers (MIACPs) have been developed.
Raju Bej +10 more
wiley +1 more source
The Use of TRAUMAGEL® for Hemorrhage Control in a Complex Head Laceration: A Case Report
David Jay Kleiman,1 Tyler Nicholas Carruth,2 James Infanzon,1,3 Marvin E Nix,1,3 Brian J Goldstone3 1Cobb County Fire and Emergency Services, Marietta, GA, USA; 2Medical Affairs, Cresilon, Inc., Brooklyn, NY, USA; 3Department of Emergency Medicine ...
Kleiman DJ +4 more
doaj
Strategies to Overcome Heparins’ Low Oral Bioavailability
Even after a century, heparin is still the most effective anticoagulant available with few side effects. The poor oral absorption of heparins triggered the search for strategies to achieve oral bioavailability since this route has evident advantages over
Ana Rita Neves +3 more
doaj +1 more source
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen +10 more
wiley +1 more source
Evolution of Left Atrial Thrombus with Anticoagulant Therapy-Follow-up by Transesophageal Echocardiography [PDF]
Cheol Ho Kim +6 more
openalex +1 more source
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang +12 more
wiley +1 more source
In vivo optical imaging enhances antibody‐drug conjugate (ADC) optimization by enabling real‐time monitoring of stimulus‐responsive drug behavior. We report n501‐CYMMAF, a ratiometric theranostic with strong target affinity and low‐dose efficacy for ovarian metastasis.
Cheng Li +8 more
wiley +1 more source

