Results 101 to 110 of about 464,460 (389)
Biomimetic glycosaminoglycan analog hydrogels exhibit suitable and robust mechanical properties, as well as hemocompatibility and biocompatibility, making them ideal for the embolization of intracranial aneurysms. Notably, the hydrogel's environment‐selective swelling properties enable complete blockage of the aneurysm cavity while preventing ...
Sarit S. Sivan+8 more
wiley +1 more source
Strategies to Overcome Heparins’ Low Oral Bioavailability
Even after a century, heparin is still the most effective anticoagulant available with few side effects. The poor oral absorption of heparins triggered the search for strategies to achieve oral bioavailability since this route has evident advantages over
Ana Rita Neves+3 more
doaj +1 more source
Background. Rodent pests are natural reservoirs and vectors of a vast array of human and animal diseases caused by bacteria, rickettsia, viruses, protozoans, fungi and some parasites. The most important risk factor for human infection with Trichinella is
Janković Ljiljana+6 more
doaj +1 more source
Anticoagulant Activity of Sulfated Ulvan Isolated from the Green Macroalga Ulva rigida
(1) Background: Brown and red algal sulfated polysaccharides have been widely described as anticoagulant agents. However, data on green algae, especially on the Ulva genus, are limited.
Amandine Adrien+5 more
semanticscholar +1 more source
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren+13 more
wiley +1 more source
Plasma oxidation following polydopamine deposition can significantly reduce the surface hydrophobicity of polyurethane‐siloxanes without impacting surface roughness, thereby increasing fibroblast viability, adhesion, and extracellular matrix production and secretion.
Sophie Armstrong+5 more
wiley +1 more source
Bleeding with direct oral anticoagulants vs warfarin: clinical experience. [PDF]
The risk of bleeding in the setting of anticoagulant therapy continues to be re-evaluated following the introduction of a new generation of direct oral anticoagulants (DOACs).
Eikelboom, John, Merli, Geno J.
core +2 more sources
IMPORTANCE Although use of oral anticoagulants (OACs) is increasing, there is a substantial lack of data on how to treat OAC-associated intracerebral hemorrhage (ICH).
J. Kuramatsu+48 more
semanticscholar +1 more source
Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley +1 more source
Engineering of a functional protein corona with a synergistic heparin‐ATIII complex significantly improves hemocompatibility of PEG nanoparticles. Through deliberate engineering of the protein corona, a 4‐fold reduction in coagulation activation (F1 + 2) without inducing adverse thromboinflammatory reactions (CD11b, C5a) is achieved without disrupting ...
Vaidehi Londhe+5 more
wiley +1 more source