Results 121 to 130 of about 354,756 (297)

Construction of Skin‐Adaptable Slide‐Ring Hydrogels Based on Bile Acids Derived Polyrotaxanes for Smart Wound Dressing

Advanced Science, EarlyView.
A novel β‐cyclodextrin/bile acid‐based slide‐ring hydrogel was prepared via precise host–guest recognition and photopolymerization. This smart hydrogel dressing exhibited skin‐adaptive mechanical properties, pH‐responsive antibacterial activity, and integrated multi‐signal sensing (temperature, blood, and pressure) for advanced wound management ...
Wen Huang, Xueru Xiong, Qian Sun, Xiangting Lai, Lili Cai, Yunhua Chen, Lin Wang, Yong‐Guang Jia   +7 more
wiley   +1 more source

Atrial fibrillation and ischaemic heart disease: should we use acetylsalicylic acid beside anticoagulants? [PDF]

, 2020
Massimo Volpe, Giovanna Gallo
openalex   +1 more source

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

Advanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo, Yingge Lv, Shuyu Huang, Chang Liu, Yan Ouyang, Bei Lan, Chenghao Xuan   +6 more
wiley   +1 more source

Real-World Bleeding Risk of Anticoagulant and Nonsteroidal Anti-inflammatory Drugs Combotherapy versus Anticoagulant Monotherapy

Gut and Liver
Background/Aims: The incidence of acute gastrointestinal bleeding (GIB) increases with the utilization of anticoagulant and nonsteroidal anti-inflammatory drugs (NSAIDs).
Moonhyung Lee, Jae Myung Cha
doaj   +1 more source

MP01-15 ANTICOAGULANTS CONTINUED DURING PVP DOES NOT IMPACT THE RISK OF POSTOPERATIVE HEMORRHAGIC COMPLICATIONS: A MULTICENTRIC PROSPECTIVE STUDY [PDF]

, 2019
Benjamin Pradère, Richard Naspro, B. Peyronnet, J. Guillotreau, B. Bordier, Kevin C. Zorn, Vicent Misrai   +6 more
openalex   +1 more source

Validation of the Safe Application of Tokyo Guideline 2018 (TG18) Severity Grading and Treatment Algorithm in Super‐Elderly Patients Aged 85 and Over With Acute Cholecystitis: A Study in the Japanese Tertiary Care Hospital

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background With population aging and extended healthy life expectancy, the management of acute cholecystitis (AC) in patients aged ≥ 85 years has evolved. However, the Tokyo Guidelines 2018 (TG18) for AC provide no specific risk assessment criteria for this population.
Yuta Kobayashi, Ryo Oikawa, Yumi Shibuya, Masakazu Tatsuno, Atsuya Kamiyama, Tsuyoshi Ozawa, Keiichiro Hara, Shinogu Hatano, Shojiro Hata, Hirokazu Yamaguchi   +9 more
wiley   +1 more source

Oral anticoagulant periprocedural management in patients undergoing an oral, dental implant or periodontal surgery: a prospective national observational survey

Research and Practice in Thrombosis and Haemostasis
Background: Oral surgery is a frequent invasive procedure in patients on oral anticoagulants. In usual care, the periprocedural management of these patients is questioned, with conflicting guidelines for patients on direct oral anticoagulants (DOACs ...
Isabelle Mahé, David Hajage, Virginie Monnet–Corti, Louis Maman, Vianney Descroix, Yann De Rycke, Loredana Radoï, Thong Nguyen, Roch Pecorari, Adeline Loing, Jonathan Ravasco, Tanguy Rouxel, Marion Renoux, Ejeil Anne-Laure, Nathan MOREAU, Marjolaine Gosset, Nicolas Roche, Ihsène Taïhi-Nassif, Nadia Benlagha, Juliette Rochefort, Rafael Toledo Arenas, Géraldine Lescaille, Marc Baranes, Anne-Cécile Becmeur, Sylvie Boisramé, Romain Lan, Jean-Hugues Catherine, Ugo Ordioni, Fabrice Campana, Anne-Gaëlle Chaux, Sylvian Catros, Jean-Marie Marteau, Johan Samot, Mathilde Fenélon, Julie Guillet, Charlene Kichenbrand, Bérengère Phulpin, Nicolas Glock, Cécile Chatel, Michel Guyot, François Allain, Julie Bemer, Alp Alantar, Catherine Pesci-Bardon, Oulimata Diatta-Tricon, Tariq Kabli, Moulay Chemlal   +46 more
doaj   +1 more source

Elevated Risk of Complications in Patients Receiving Dual Antithrombotic Therapy Undergoing Hepatectomy: A Single‐Center Audit of 749 Cases

Annals of Gastroenterological Surgery, EarlyView.
This single‐center retrospective study evaluated perioperative outcomes after hepatectomy in 749 patients, including 140 receiving ATT, using propensity score matching to compare ATT and non‐ATT cohorts. Under standardized perioperative management, ATT did not increase major bleeding, transfusion, or severe morbidity overall; however, within the ATT ...
Haruki Mori, Hiromitsu Maehira, Nobuhito Nitta, Takeru Maekawa, Toru Miyake, Sachiko Kaida, Masatsugu Kojima, Katsushi Takebayashi, Takeshi Sonoda, Masaji Tani   +9 more
wiley   +1 more source

Preclinical Evaluation of the Anticoagulant Effect of an Aqueous Extract of Snow Mountain Garlic

Medicina
Background/Objectives: In the genus Allium, it has been shown that some organosulfate compounds of common garlic and onion have an antiplatelet effect.
Isabel Clark-Montoya, Rosa del Carmen Milán-Segovia, Obed Lemus-Rojero, Osmar Antonio Jaramillo-Morales, Bertha Júarez-Flores, Yolanda Terán-Figueroa   +5 more
doaj   +1 more source

Prognostic Significance of Portal Vein Tumor Thrombus in Pancreatic Ductal Adenocarcinoma Treated With Chemoradiotherapy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim To examine the significance of portal vein tumor thrombus (PVTT) as a prognostic factor for patients with pancreatic ductal adenocarcinoma (PDAC) treated with chemoradiotherapy (CRT) followed by surgery. Methods The study retrospectively examined 313 patients with borderline resectable (BR) or locally advanced (LA) PDAC who underwent CRT ...
Aoi Hayasaki, Motonori Nagata, Miki Usui, Hiroshi Imai, Yusuke Iizawa, Akihiro Tanemura, Yasuhiro Murata, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno   +9 more
wiley   +1 more source