Results 171 to 180 of about 464,460 (389)

Preliminary Report on the Clinical Use of a New Anticoagulant, Phenylindandione [PDF]

open access: bronze, 1950
ANCEL U. BLAUSTEIN   +3 more
openalex   +1 more source

A Pump‐Free, Hydraulic‐Amplification Oscillatory Microfluidic Device for Continuous Particle and Cell Manipulation

open access: yesAdvanced Science, EarlyView.
This study demonstrates a pump‐free, hydraulic‐amplification oscillatory microfluidic device, which generates oscillatory flows by deforming flexible microchannels through reciprocating finger pressing. The mechanism of elasto‐inertial focusing in the oscillatory flows is revealed, and early detection of drug‐treated platelet aggregates and rapid cell ...
Yong Liu   +3 more
wiley   +1 more source

Comparison of two reducing agents dithiothreitol and tris(3-hydroxypropyl)phosphine for in vitro kinetic assay of vitamin K epoxide reductase

open access: yesVeterinary and Animal Science, 2020
Vitamin K epoxide reductase (VKOR) is a target enzyme for anticoagulants, such as warfarin, that are used as medicines or rodenticides. Assessing VKOR activity is required to ensure the proper usage of these drugs.
Kazuki Takeda   +4 more
doaj  

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He   +11 more
wiley   +1 more source

Anticoagulation

open access: yes
This chapter aims to summarize the most relevant aspects of anticoagulants. Initially, a brief review of the physiology is given in order to understand at which step of coagulation each anticoagulant acts. Later, the main indications and contraindications will be discussed, as well as the considerations that should be taken into account before starting
Hernando, Nieto, Raquel   +5 more
openaire   +2 more sources

A Nano‐Electro‐Platform Enabling Evolutionary Screening and Remodeling of Tumor Cells for Metastasis Inhibition

open access: yesAdvanced Science, EarlyView.
The nano‐electro‐platform achieves non‐destructive evolutionary screening and electro‐remodeling of tumor cells to generate extracellular vesicles with enhanced tumor‐targeting and therapeutic functions. These extracellular vesicles demonstrate remarkable efficacy in activating both macrophages and T cells, thereby orchestrating a potent immune ...
Feng Liu   +20 more
wiley   +1 more source

MOF Coating Enhances the Ion Tolerance of Micromotors

open access: yesAngewandte Chemie, EarlyView.
This work reported a novel method to significantly enhance the ion tolerance of EMNMs using a MOF coating via controllable heteroepitaxial growth, enabling effective motion in high‐salt environments and propulsion through biological tissues under 980 nm NIR light, with potential applications in targeted drug delivery.
Leyan Ou   +10 more
wiley   +2 more sources

Clinical Use of the Anticoagulant Phenylindanedione [PDF]

open access: bronze, 1952
Frederick W. Preston   +3 more
openalex   +1 more source

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