Results 231 to 240 of about 482,975 (382)

Design, Synthesis, and Molecular Docking of Triazole‐Coumarin Hybrids as Potent Breast Cancer Inhibitors Targeting Cell Cycle and Apoptosis

open access: yesChemistry &Biodiversity, EarlyView.
Triazole‐coumarin hybrids were synthesized as breast cancer inhibitors. Derivative 5f induced S‐phase arrest and apoptosis in cancer cells, with minimal toxicity to healthy cells, showing promise for anticancer drug development. ABSTRACT Breast cancer continues to pose a significant global health burden, highlighting the urgent need for novel ...
Murat Keser   +4 more
wiley   +1 more source

Anticoagulant treatment for subsegmental pulmonary embolism [PDF]

open access: bronze, 2020
Hugo Hyung Bok Yoo   +2 more
openalex   +1 more source

Human Protein Z as the Second Known Heme‐Binding Protein from the Endogenous Blood Coagulation Inhibitor System

open access: yesChemBioChem, EarlyView.
Protein Z is a vitamin K‐dependent anticoagulant with elusive molecular functions. Herein, it is shown that heme binds to protein Z and induces conformational changes. One histidine‐based heme‐binding motif is identified. High heme‐binding affinity and functional effects are demonstrated on protein level. These findings shed new light on the structural
Paula Lindemann, Marie‐T. Hopp
wiley   +1 more source

Endomyocardial Fibrosis Associated With Hypereosinophilic Syndrome: Diagnostic and Management Insights From a Case Report

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Endomyocardial fibrosis (EMF) is a rare form of restrictive cardiomyopathy associated with eosinophilic disorders, characterized by apical subendocardial fibrosis and thrombus formation. Cardiac magnetic resonance (CMR) provides a comprehensive, noninvasive evaluation, enabling diagnosis, assessment of disease activity, and guidance of therapy.
Ibrahim Antoun   +3 more
wiley   +1 more source

Anticoagulant therapy and altered tissue factor expression protect against experimental placental and cerebral malaria

open access: gold
Alicer K. Andrew   +7 more
openalex   +1 more source

A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents.

open access: yesNew England Journal of Medicine, 1996
A. Schömig   +11 more
semanticscholar   +1 more source

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