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The Case for Anticoagulant Therapy [PDF]

open access: bronzeCirculation, 1964
In summary, the total world evidence suggests that in the absence of compelling contraindications and with the availability of satisfactory laboratory and clinical facilities, patients suffering with acute myocardial infarction should receive adequate anticoagulant therapy during the first month, and that the risk of reinfarction and death is reduced ...
Irving S. Wright
openalex   +4 more sources

A Guide to Anticoagulant Therapy [PDF]

open access: bronzeCirculation, 1961
The physician who undertakes anticoagulant therapy tampers with one of the most important homeostatic functions of the body. In so doing, he subjects the patient to the calculated hazard of possible hemorrhage balanced against the risks of the thrombosis or embolism that he seeks to prevent or treat.
Benjamin Alexander, Stanford Wessler
openalex   +5 more sources

Prophylactic anticoagulant therapy is associated with improved survival in ICU patients with non-COVID-19 pneumonia: a retrospective cohort study [PDF]

open access: yesFrontiers in Pharmacology
BackgroundCoagulation disorders are common complications in patients with pulmonary infections. Studies have suggested beneficial effects of anticoagulant therapies in patients with COVID-19.
Haiming Hu   +14 more
doaj   +2 more sources

Oral anticoagulant therapy

open access: yesIndian Journal of Dental Research, 2012
Pankaj Agarwal
doaj   +4 more sources

Retroperitoneal hematoma: An unexpected complication of anticoagulant therapy in COVID-19 patients [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2023
Introduction. Coronavirus disease 2019 (COVID-19) is associated with high inflammatory response, hemostatic disturbances, and high thrombotic risk. Despite thromboprophylaxis, a high incidence of thromboembolic events has been reported with a consequent ...
Vasković Igor   +4 more
doaj   +1 more source

The risk of recurrent venous thromboembolism after discontinuation of anticoagulant therapy in patients with cancer-associated thrombosis: a systematic review and meta-analysisResearch in context

open access: yesEClinicalMedicine, 2023
Summary: Background: The optimal duration of anticoagulation in patients with active cancer and venous thromboembolism (VTE) is unknown. Current clinical guidelines advocate anticoagulant therapy for 3–6 months and to continue anticoagulant therapy for ...
Marte A.M. van Hylckama Vlieg   +22 more
doaj   +1 more source

Age-related differences in the survival benefit of the administration of antithrombin, recombinant human thrombomodulin, or their combination in sepsis

open access: yesScientific Reports, 2022
Disseminated intravascular coagulation (DIC) is one of the major organ dysfunctions associated with sepsis. This retrospective secondary analysis comprised data from a prospective multicenter study to investigate the age-related differences in the ...
Takeshi Wada   +30 more
doaj   +1 more source

Anticoagulant Therapy Is Associated With Decreased Long-Term Mortality in Splenic Infarction Patients: A Multicenter Study

open access: yesFrontiers in Medicine, 2021
Background: Patients with splenic infarction (SI) are associated with a prothrombotic state and are vulnerable to subsequent thromboembolic complications. However, due to its rarity, there is no established treatment modality in this population. We aimed
Chieh-Ching Yen   +13 more
doaj   +1 more source

Magnitude of hemorrhagic complications and its associated factors among patients on anticoagulant therapy at University of Gondar Comprehensive and Specialized Hospital, Northwest Ethiopia

open access: yesThrombosis Update, 2023
Background: Despite the well-established effectiveness of anticoagulants, the risk of their hemorrhagic complications withheld many patients from being maintained on anticoagulant therapy. However, there is no sufficient data on the magnitude and factors
Eden Abetu Mehari   +3 more
doaj   +1 more source

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