Results 121 to 130 of about 4,600,401 (406)
Should oral anticoagulant therapy be continued during dental extraction? A meta-analysis
BMC Oral Health, 2016 BackgroundOral anticoagulation therapy is widely used to reduce the risks of thromboembolism. However, the therapy increases the risk of hemorrhage during the surgical procedures.
Shuo Yang +4 more
semanticscholar +1 more source
Managing atrial fibrillation in the global community: The European perspective. [PDF]
, 2013 Atrial fibrillation is a common, global problem, with great personal, economic and social burdens. As populations age it increases in prevalence and becomes another condition that requires careful chronic management to ensure its effects are minimised ...
Camm, AJ +3 more
core +1 more source
Safety and Efficacy of Anticoagulation in Patients with Cirrhosis: A Meta-Analysis
Canadian Journal of Gastroenterology and Hepatology, 2021 Background and Aims. Portal vein thrombosis is a serious adverse event that occurs during liver cirrhosis. We performed a meta-analysis to evaluate the safety and efficacy of anticoagulant therapy and prophylactic anticoagulant therapy in cirrhosis ...
Huan Chen +5 more
doaj +1 more source
Advanced Science, EarlyView.Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li +9 more
wiley +1 more source
Challenges in constructing genetic instruments for pharmacologic therapies [PDF]
arXiv, 2020 The genes that encode the targets of most therapies do not have rare variants with large-effect or common variants with moderate effects on the biomarker reflecting the pharmacologic action of the corresponding therapy. Therefore, providing genetic target validation for most therapies is challenging.
arxiv
Advanced Science, EarlyView.During a heart attack, neutrophils rapidly activate and differentiate into a specific subset characterized by high levels of MMP9, a tissue‐damaging enzyme, via the SPI1/CST7 pathway. These neutrophils form harmful net‐like structures (Neutrophil extracellular traps, NETs) that exacerbate heart injury.
Shiyu Hu +13 more
wiley +1 more source
New oral anticoagulants and their reversal agents [PDF]
, 2018 Atrial fibrillation is a commonly encountered pathology in medical practice, and its prevalence has shown a continuous rise over the past years. Atrial fibrillation has a significant impact on patients\u27 quality of life, not only due to the standard ...
Bodean, Oana +9 more
core +1 more source
Rapid Blood Clot Removal via Remote Delamination and Magnetization of Clot Debris
Advanced Science, EarlyView.A programmable colloidal microswarm is developed to quickly detach blood clots and enable rapid recanalization, with the detached debris functioning as a magnetic “debris‐robot” that can be efficiently propelled and retrieved via catheter suction, which could significantly save time compared to the critical “Golden 6 hours” window for ischemic stroke ...
Qinglong Wang +11 more
wiley +1 more source
Europace, 2015 AIMS To study the risk of thromboembolism in a nationwide cohort of atrial fibrillation patients undergoing direct current (DC) cardioversion with or without oral anticoagulant coverage.
M. L. Hansen +9 more
semanticscholar +1 more source
Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy
Advanced Science, EarlyView.Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu +6 more
wiley +1 more source