Results 131 to 140 of about 189,595 (350)

Protein S Enhances the Phagocytosis of Phosphatidylserine‐Exposing Erythrocytes: Implications in Sickle Cell Disease

American Journal of Hematology, EarlyView.
ABSTRACT The major anticoagulant Protein S (PROS1) also contributes to the phagocytosis of apoptotic cells by bridging exposed phosphatidylserine (PtdSer) to the MerTK receptor on macrophages (efferocytosis). Whether PROS1 is involved in the splenic clearance of PtdSer‐positive senescent and altered erythrocytes such as erythrocyte ghosts (eryghosts ...
Claire Auditeau, Aurélie Fricot, Raphaël Gauthier, Abdoulaye Sissoko, Zeynep Cacan, Céline Gounou, Laure Joseph, Sandra Manceau, Slimane Allali, Michael Dussiot, Mickael Marin, Alexis Lavergne, Mariem Khamari, Sophie Moog, Elsa Bianchini, Laetitia Claer, Sandrine Laurance, Valentine Brousse, Sébastien Eymieux, Philippe Roingeard, Pascal Amireault, Thiago Trovati Maciel, Alain Brisson, Pierre Buffet, François Saller, Delphine Borgel, Camille Roussel   +26 more
wiley   +1 more source

Cerebrovascular Disease: Trial of Long-term Anticoagulant Therapy [PDF]

, 1962
A. Bradford Hill, John Marshall, D.A. Shaw   +2 more
openalex   +1 more source

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

Annals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek, David F. Hanff, Pim J. French, Sarah A. van Dijk, Erik A.C. Wiemer, Olivier C. Manintveld, Martin J. van den Bent, Walter Taal   +7 more
wiley   +1 more source

Peculiarities of diagnostics and treatment of chronic generalized periodontitis in patients with heart rhythm disorders taking anticoagulants

Эндодонтия Today
INTRODUCTION. A clinical examination and treatment were conducted on 104 patients with cardiac arrhythmias who were receiving anticoagulant therapy.
M. V. Lomakina, A. G. Volkov, V. M. Grinin, N. Zh. Dikopova, L. V. Abolyan, I. A. Nikolskaya   +5 more
doaj   +1 more source

London SynEx Demonstrator Site: Impact Assessment Report [PDF]

, 2000
The key ingredients of the SynEx-UCL software components are: 1. A comprehensive and federated electronic healthcare record that can be used to reference or to store all of the necessary healthcare information acquired from a diverse range of clinical
Austin, A., Ingram, D., Kalra, D., Lloyd, D., O’Connor, A., Patterson, D.   +5 more
core  

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Problems Associated with Long-Term Anticoagulant Therapy [PDF]

, 1962
J.W. Pollard, Michael Hamilton, Norman A. Christensen, Richard W. P. Achor   +3 more
openalex   +1 more source

MEW/PVA‐MA Hydrogel Vascular Grafts: Enhancing Hemocompatibility and Endothelialization

Advanced NanoBiomed Research, EarlyView.
A biomimetic vascular graft combining biofunctionalized PVA‐MA hydrogels with a MEW scaffold is developed for small‐diameter applications. Gel‐MA and Hep‐MA incorporation enhances endothelialization and hemocompatibility, respectively, targeting the acute biological responses.
Verena Kronberger, Shouyuan Jiang, Minh H. Ho, Jasneil Singh, Chung‐Wei (Roy) Hsu, Gabriella C. J. Lindberg, Khoon S. Lim, Tomasz Jungst, Anna Waterhouse   +8 more
wiley   +1 more source

Levels of Blood-coagulation Factors During Anticoagulant Therapy with Phenindione [PDF]

, 1961
K. W. E. Denson
openalex   +1 more source

Antiphospholipid Syndrome: An Antibody‐Mediated Disease With Emerging Therapeutic Opportunities

Arthritis &Rheumatology, EarlyView.
Antiphospholipid syndrome (APS) is an autoimmune thromboinflammatory disease characterized by vascular thrombosis, pregnancy morbidity, and other manifestations driven by antiphospholipid autoantibodies. In this review, we present a clinical case that illustrates some diagnostic and therapeutic challenges in managing severe, relapsing APS ...
Thalia G. Newman, Jason S. Knight
wiley   +1 more source