Results 151 to 160 of about 195,691 (306)
Individualising Anticoagulant Therapy in Atrial Fibrillation Patients
, 2016 Marco Ailings
openalex +1 more source
Arthritis &Rheumatology, EarlyView.Objective International criteria for antiphospholipid syndrome (APS) include lupus anticoagulant (LA), anticardiolipin (aCL) IgG and IgM, and anti–β2‐glycoprotein I (β2GPI) IgG and IgM. However, evidence supporting their prognostic value or treatment efficacy in improving live birth rates is limited.
Megumi Nonobe +8 more
wiley +1 more source
Empowering patients to self-control and self-management of anticoagulant therapy [PDF]
, 2023 Andreja Hrovat Bukovšek, Bojana Filej
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Prothrombotic Activation of Platelet Pannexin 1 Channels in Antiphospholipid Syndrome
Arthritis &Rheumatology, Accepted Article.Background ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. Objective To evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired thrombo‐inflammatory ...
Bruna de Moraes Mazetto Fonseca +13 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Antiphospholipid syndrome (APS) is a thrombo‐inflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)‐positive patients using whole‐blood transcriptomics.
Amala Ambati +13 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims To assess the utility of the artificial intelligence (AI) chatbot ChatGPT (openly available version 3.5) in responding to real‐world pharmacotherapeutic queries from healthcare professionals. Methods Three independent and blinded evaluators with different levels of medical expertise and professional experience (beginner, advanced, and expert ...
Benjamin Krichevsky +9 more
wiley +1 more source
Prior antiplatelet or anticoagulant therapy and mortality in stroke [PDF]
, 2012 Chun Shing Kwok +4 more
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British Journal of Clinical Pharmacology, EarlyView.Aims To translate a PBPK model developed for the direct oral anticoagulant, dabigatran etexilate, the prodrug of dabigatran, based on data obtained from healthy men to healthy non‐pregnant, pregnant and post‐partum women. To evaluate safety and efficacy of dabigatran etexilate in post‐partum women using simulations and design a future clinical study to
Kayode Ogungbenro +3 more
wiley +1 more source