Results 151 to 160 of about 4,684,794 (400)

The Prevention of Thromboembolic Complications in Myocardial Infarction by Anticoagulant Therapy [PDF]

, 1956
Helen I. Glueck, Henry W. Ryder, P. Wasserman   +2 more
openalex   +1 more source

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

Advanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen, YuWei Zhou, LongXiang Sheng, FangYing Mai, YuXuan Ding, ShiRan Hong, JiaXin Wu, JiaKai Pi, GuangMei Yan, YiJun Huang, JingJing Duan, Xuefeng Hua, Wei Yin   +12 more
wiley   +1 more source

Design and implementation of a federated health record server [PDF]

, 2001
This paper describes the practical implementation of a federated health record serverbased on a generic and comprehensive public domain architecture and deployed in alive clinical setting.The authors, working at the Centre for Health Informatics and ...
Austin, A, Ingram, D, Kalra, D, Lloyd, D, O'Connor, A, Patterson, D   +5 more
core  

Prolonged Anticoagulant Therapy with Heparin [PDF]

, 1952
A. Wynn, J. F. Goodwin, A. Birbeck
openalex   +1 more source

Critical Role of IL1R2‐ENO1 Interaction in Inhibiting Glycolysis‐Mediated Pyroptosis for Protection Against Lethal Sepsis

Advanced Science, EarlyView.
The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan, Han Ma, Jespar Chen, Gaifeng Ma, Alok Jha, Sipin Tan, Yaxi Zhu, Meidong Liu, Ke Liu, Xianzhong Xiao, Monowar Aziz, Huan Chen, Ping Wang, Huali Zhang   +13 more
wiley   +1 more source

Portal vein thrombosis : a case report and literature review [PDF]

, 2013
A case report of Portal Vein Thrombosis (PVT) as a complication of protein S deficiency. PVT has been increasingly diagnosed over the years, particularly through the use of ultrasound-Doppler equipment.
Cuschieri, Sarah, Gauci, James, Vassallo, Mario   +2 more
core  

Levels of Blood-coagulation Factors During Anticoagulant Therapy with Phenindione [PDF]

, 1961
K. W. E. Denson
openalex   +1 more source

Red Blood Cell Membrane Lipidomics: Potential Biomarkers Detecting Method for Plasma Volume Overload and Major Adverse Cardiovascular Events in Chronic Heart Failure Patients

Advanced Science, EarlyView.
A novel RBC indicator, ESI, is better than the traditional RBC indicators and is associated with CHF prevalence and in‐hospital death. RBC membrane lipidomics, Cer 18:0;O2/16:0, and LPE 18:0, are associated with plasma volume overload and MACE in CHF patients, but these plasma lipids could not.
Lin Zhang, Xiangqin Ou, Jingyi Lin, Xiaofei Luo, Jiashun Zhou, Xingyue Zhou, Peihua Zhao, Li Liu, Ziran Zhao, Ying Zhou, Guanwei Fan, Lifeng Han, Xiumei Gao   +12 more
wiley   +1 more source

Cerebrovascular Disease: Trial of Long-term Anticoagulant Therapy [PDF]

, 1962
A. Bradford Hill, John Marshall, D.A. Shaw   +2 more
openalex   +1 more source

A Multi‐Property Optimizing Generative Adversarial Network for de novo Antimicrobial Peptide Design

Advanced Science, EarlyView.
A Multi‐Property Optimizing Generative Adversarial Network (MPOGAN) is proposed to iteratively learn the relationship between peptides and multiple properties using a dynamically dataset. As the quality of the dataset improves, MPOGAN's ability to design antimicrobial peptides (AMPs) with multiple desired properties is enhanced.
Jiaming Liu, Tao Cui, Tao Wang, Lishan Lin, Xi Zeng, Dazhi Lu, Shaoqing Jiao, Jun Wang, Xiaoyan Li, Shuyuan Xiao, Dongna Xie, Xuecheng Wang, Yongtian Wang, Xuequn Shang, Yinbo Niu, Zhongyu Wei, Jiajie Peng   +16 more
wiley   +1 more source