Results 171 to 180 of about 4,684,794 (400)

Nanoparticle Drug Delivery Systems for Atherosclerosis: Precision Targeting, Inflammatory Modulation, and Plaque Stabilization

open access: yesAdvanced Science, EarlyView.
This review first summarizes the complex pathogenesis of atherosclerosis and outlines the limitations of conventional therapies. It then explores innovative nanoparticle drug delivery system (NDDS) developments, detailing their precision targeting strategies, responsiveness to plaque‐specific stimuli, modulation of key pathological processes, and ...
Yunqi Zhang   +13 more
wiley   +1 more source

Personalized anticoagulant therapy strategies for deep vein thrombosis

open access: yesZhongguo linchuang yanjiu
Deep vein thrombosis (DVT) is a common vascular condition that can lead to severe complications such as pulmonary embolism and chronic post-thrombotic syndrome. Anticoagulant therapy is the cornerstone of DVT management.
GONG Maofeng, GU Jianping
doaj   +1 more source

London SynEx Demonstrator Site: Impact Assessment Report [PDF]

open access: yes, 2000
The key ingredients of the SynEx-UCL software components are: 1. A comprehensive and federated electronic healthcare record that can be used to reference or to store all of the necessary healthcare information acquired from a diverse range of clinical
Austin, A.   +5 more
core  

Senescence‐Inducing Therapy Sequential NIR‐II Mild Photothermal/Senolytic Therapy of Triple Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Targeting triple‐negative breast cancer remains challenging due to limited therapies and drug resistance. A sequential theranostic strategy combining palbociclib‐induced senescence (enhancing heat sensitivity via HSP70 downregulation) with an NIR‐II nanoplatform (IQ NPs) for mild photothermal therapy (PTT) and quercetin‐mediated senolysis is developed.
Liya Yu   +8 more
wiley   +1 more source

Postoperative care in finger replantation. Our case-load and review of the literature [PDF]

open access: yes, 2015
OBJECTIVE: Technical success of a finger replantation depends on several factors such as surgical procedure, type of injury, number of segments amputated, amputation level and individual patient factors.
Chen, Hc   +6 more
core  

Assessing Extracellular Vesicle Turnover In Vivo Using Highly Sensitive Phosphatidylserine‐Binding Reagents

open access: yesAdvanced Science, EarlyView.
Extracellular vesicles (EVs) are promising biomarkers, but their heterogeneity limits clinical use. A novel high‐affinity phosphatidylserine (PS)‐binding reagent is introduced that reveals ≈90% of circulating EVs are PS⁺. This enables in vivo tracking, showing rapid EV clearance and retention in spleen immune cells—advancing EV quantification ...
Lavinia Flaskamp   +9 more
wiley   +1 more source

A Nano‐Electro‐Platform Enabling Evolutionary Screening and Remodeling of Tumor Cells for Metastasis Inhibition

open access: yesAdvanced Science, EarlyView.
The nano‐electro‐platform achieves non‐destructive evolutionary screening and electro‐remodeling of tumor cells to generate extracellular vesicles with enhanced tumor‐targeting and therapeutic functions. These extracellular vesicles demonstrate remarkable efficacy in activating both macrophages and T cells, thereby orchestrating a potent immune ...
Feng Liu   +20 more
wiley   +1 more source

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