Results 171 to 180 of about 4,684,794 (400)
This review first summarizes the complex pathogenesis of atherosclerosis and outlines the limitations of conventional therapies. It then explores innovative nanoparticle drug delivery system (NDDS) developments, detailing their precision targeting strategies, responsiveness to plaque‐specific stimuli, modulation of key pathological processes, and ...
Yunqi Zhang+13 more
wiley +1 more source
Personalized anticoagulant therapy strategies for deep vein thrombosis
Deep vein thrombosis (DVT) is a common vascular condition that can lead to severe complications such as pulmonary embolism and chronic post-thrombotic syndrome. Anticoagulant therapy is the cornerstone of DVT management.
GONG Maofeng, GU Jianping
doaj +1 more source
London SynEx Demonstrator Site: Impact Assessment Report [PDF]
The key ingredients of the SynEx-UCL software components are: 1. A comprehensive and federated electronic healthcare record that can be used to reference or to store all of the necessary healthcare information acquired from a diverse range of clinical
Austin, A.+5 more
core
Targeting triple‐negative breast cancer remains challenging due to limited therapies and drug resistance. A sequential theranostic strategy combining palbociclib‐induced senescence (enhancing heat sensitivity via HSP70 downregulation) with an NIR‐II nanoplatform (IQ NPs) for mild photothermal therapy (PTT) and quercetin‐mediated senolysis is developed.
Liya Yu+8 more
wiley +1 more source
Postoperative care in finger replantation. Our case-load and review of the literature [PDF]
OBJECTIVE: Technical success of a finger replantation depends on several factors such as surgical procedure, type of injury, number of segments amputated, amputation level and individual patient factors.
Chen, Hc+6 more
core
Extracellular vesicles (EVs) are promising biomarkers, but their heterogeneity limits clinical use. A novel high‐affinity phosphatidylserine (PS)‐binding reagent is introduced that reveals ≈90% of circulating EVs are PS⁺. This enables in vivo tracking, showing rapid EV clearance and retention in spleen immune cells—advancing EV quantification ...
Lavinia Flaskamp+9 more
wiley +1 more source
Clinical Experience with Anticoagulant Therapy During Pregnancy [PDF]
J. Hirsh, J. F. Cade, E. F. O'Sullivan
openalex +1 more source
The nano‐electro‐platform achieves non‐destructive evolutionary screening and electro‐remodeling of tumor cells to generate extracellular vesicles with enhanced tumor‐targeting and therapeutic functions. These extracellular vesicles demonstrate remarkable efficacy in activating both macrophages and T cells, thereby orchestrating a potent immune ...
Feng Liu+20 more
wiley +1 more source