Results 241 to 250 of about 4,600,401 (406)

Anticoagulant therapy in COVID-19: A narrative review. [PDF]

open access: yesClin Transl Sci, 2023
Mohseni Afshar Z   +9 more
europepmc   +1 more source

A Benchmark, Expand, and Calibration (BenchExCal) Trial Emulation Approach for Using Real‐World Evidence to Support Indication Expansions: Design and Process for a Planned Empirical Evaluation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence involving healthcare database studies is well established for making causal inferences in post‐market drug safety studies and methods, data, and research infrastructure for evaluating effectiveness have advanced in recent years. The rapidly expanding field of etiologic research using insurance claims and electronic health records ...
Shirley V. Wang   +6 more
wiley   +1 more source

Impact of Age and Factor Xa Inhibitor Concentrations on Bleeding Risk in Patients with Atrial Fibrillation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
This study aimed to analyze differences in the exposure‐response relationship for factor Xa inhibitors (FXaI) between patients aged ≥ 80 and < 80 years. Patients with atrial fibrillation (AF) taking rivaroxaban, apixaban, or edoxaban were enrolled, and a single steady‐state trough concentration was measured.
Shin‐Yi Lin   +7 more
wiley   +1 more source

Clinical outcomes and hemorrhagic or thromboembolic risks in decompressive craniectomy for patients taking antiplatelet or anticoagulant therapy. [PDF]

open access: yesNeurosurg Rev
Scerrati A   +28 more
europepmc   +1 more source

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