Results 61 to 70 of about 195,691 (306)

Dicumarol [PDF]

, 1945
Thesis (M.D.)--Boston ...
Steel, Robert MacDonald
core  

Hepatic artery thrombosis after pediatric liver transplantation a medical or surgical event [PDF]

, 1989
Hepatic artery thrombosis (HAT) is one of the most serious complications after orthotopic liver transplan¬tation, and is associated with a high morbidity and mor¬tality.
Andrei, CS, Andres, GT, Baburao, K, Carlos, E, Delawir, K, Leonard, M, Satoru, T, Steven, B, Thomas, ES, Velma, PS, Vincenzo, M   +10 more
core   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Thromboembolic and neurologic sequelae of discontinuation of an antihyperlipidemic drug during ongoing warfarin therapy [PDF]

, 2017
Warfarin and antihyperlipidemics are commonly co-prescribed. Some antihyperlipidemics may inhibit warfarin deactivation via the hepatic cytochrome P450 system.
Bilker, Warren B., Brensinger, Colleen M., Hennessy, Sean, Kimmel, Stephen E., Leonard, Charles E., Whitaker, Heather J.   +5 more
core   +2 more sources

Adaptive 4D‐Printed Vascular Stents With Low‐Temperature‐Activated and Intelligent Deployment

Advanced Functional Materials, EarlyView.
Microarchitected coronary artery stents were fabricated using a polycaprolactone (PCL)‐based shape memory polymer (SMP) composite via projection micro‐stereolithography (PµSL) 4D printing. By incorporating diethyl phthalate (DEP) as a plasticizer, the thermal transition temperature (Ttran) was modulated to about 37°C, enabling rapid and autonomous ...
Yannan Li, Yifan Pan, Chikahiro Imashiro, Chaolun Xu, Jianxian He, Jingao Xu, Kewei Song, Ze Zhang, Chen Gao, Junbo Jiang, Runhuai Yang, Kayo Hirose, Shinjiro Umezu   +12 more
wiley   +1 more source

An Analysis of Perceived and Actual Anticoagulant Knowledge among Independent Pharmacy Patients

INNOVATIONS in Pharmacy, 2020
Background: Deficits in knowledge of parameters surrounding anticoagulant therapy administration carry substantial risks for patient harm. Patients prescribed anticoagulants may overestimate their knowledge of anticoagulant use principles. The purpose of
Kenric Ware, Marty Faile, Carrie Lynch
doaj   +1 more source

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Nomenclature for renal replacement therapy and blood purification techniques in critically ill patients: practical applications [PDF]

, 2016
This article reports the conclusions of the second part of a consensus expert conference on the nomenclature of renal replacement therapy (RRT) techniques currently utilized to manage acute kidney injury and other organ dysfunction syndromes in ...
Bagshaw, S. M., Balducci, A., Baldwin, I., Barbarigo, F., Bellomo, R., Bellomo, Rinaldo, Braganã³, P., Braunsky, J., Calletti, F., Cerda, J., Cerda, Jorge, Chawla, L., De Gaudio, A. Raffaele, De Rosa, S., De Rosa, Silvia, Di Somma, S., Doi, K., Dosil Rosende, P., Emmett, M., Fecondini, L., Galavotti, D., Garzotto, F., Garzotto, Francesco, Gibney, N., Goldstein, S. L., Guadagni, G., Honore, Patrick M., Honorã, P., Hoste, E., Inadome, S., Kashani, K., Katz, N., Kellum, J., Kenley, R., Kobayashi, Y., Lannoy, J., Lewington, A., Lorenzin, Anna, Mariano, F., Mccullough, P. A., Mehta, R. L., Menneguerre, J., Mettifogo, M., Neri, M., Neri, Mauro, Ostermann, M., Pani, A., Payen, Didier, Pirazzoli, P., Pohlmeier, R., Pouchoulin, D., Ricci, Z., Ricci, Zaccaria, Ronco, C., Ronco, Claudio, Rosner, M., Samoni, Sara, Seamann, M., Shaw, A., Tolwani, A., Villa, G., Villa, Gianluca, Vincent, J. L., Vincent, Jean-Louis, Wendon, J., Wendon, Julia, Zaccaria, Marta   +66 more
core   +4 more sources

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source