Results 81 to 90 of about 4,600,401 (406)

Endoscopy in patients on antiplatelet or anticoagulant therapy, including direct oral anticoagulants: British Society of Gastroenterology (BSG) and European Society of Gastrointestinal Endoscopy (ESGE) guidelines

Gut, 2016
The risk of endoscopy in patients on antithrombotics depends on the risks of procedural haemorrhage versus thrombosis due to discontinuation of therapy. P2Y12 receptor antagonists (clopidogrel, prasugrel, ticagrelor) For low-risk endoscopic procedures we
A. Veitch, G. Vanbiervliet, A. Gershlick, C. Boustière, T. Baglin, L. Smith, F. Radaelli, E. Knight, I. Gralnek, C. Hassan, J. Dumonceau   +10 more
semanticscholar   +1 more source

Protocol for a modelling study to assess the clinical and cost-effectiveness of indefinite anticoagulant therapy for first unprovoked venous thromboembolism

BMJ Open, 2023
Introduction Deciding whether to stop or extend anticoagulant therapy indefinitely after completing at least 3 months of initial treatment for a first unprovoked venous thromboembolism (VTE) remains a challenge for clinicians, patients and policy makers.
Marc Rodger, Grégoire Le Gal, Kednapa Thavorn, Faizan Khan, Tobias Tritschler, Dean Fergusson, Doug Coyle, Sasha van Katwyk   +7 more
doaj   +1 more source

Oral Anticoagulant Therapy Prescription in Patients With Atrial Fibrillation Across the Spectrum of Stroke Risk: Insights From the NCDR PINNACLE Registry.

JAMA cardiology, 2016
IMPORTANCE Patients with atrial fibrillation (AF) are at a proportionally higher risk of stroke based on accumulation of well-defined risk factors. OBJECTIVE To examine the extent to which prescription of an oral anticoagulant (OAC) in US cardiology ...
J. Hsu, T. Maddox, K. Kennedy, David F. Katz, Lucas N Marzec, S. Lubitz, A. Gehi, M. Turakhia, G. Marcus   +8 more
semanticscholar   +1 more source

Evidence supporting idarucizumab for the reversal of dabigatran. [PDF]

, 2016
Idarucizumab is a monoclonal antibody fragment specifically targeted to dabigatran. It has demonstrated prompt and durable reversal of the anticoagulant effects of dabigatran in animal studies and phase 1 studies of young, elderly, and renally impaired ...
Pollack, Charles V.
core   +2 more sources

Poor expression of miR‐195‐5p can assist the diagnosis of cerebral vasospasm after subarachnoid hemorrhage and predict adverse outcomes

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Objective Patients with spontaneous subarachnoid hemorrhage (SAH) may develop refractory arterial cerebral vasospasm (CVS), which is the leading cause of death in SAH patients. This study explored the clinical diagnostic value of serum miR‐195‐5p levels in CVS after SAH (SAH + CVS) and its relationship with the prognosis of SAH + CVS.
Yong Li, Senyuan Yang, Xiaobin Zhou, Runlong Lai   +3 more
wiley   +1 more source

Changing the approach to anticoagulant therapy in older patients with multimorbidity using a precision medicine approach [PDF]

, 2018
The ageing of the world population has resulted in an increase in the number of older patients with multimorbid conditions receiving multiple therapies.
Capi, Matilde, Koverech, Angela, Lionetto, Luana, Martelletti, Paolo, Negro, Andrea, Polidori, Vittoria, Pomes, Leda Marina, Simmaco, Maurizio, Soldati, Valeriano   +8 more
core   +1 more source

SELECTING AN OPTIMAL LONG-TERM ANTICOAGULANT THERAPY FOR A PATIENT WITH ATRIAL FIBRILLATION AND RECURRENT MINOR HEMORRHAGE. CLINICAL FOLLOW-UP

Атеротромбоз, 2017
For patients with atrial fibrillation, long-term oral anticoagulant therapy reduces the risk of ischemic stroke and systemic embolism, while increasing the risk of hemorrhagic complications.
E. S. Kropacheva, E. P. Panchenko
doaj   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Older patients with COVID‐19 and neuropsychiatric conditions: A study of risk factors for mortality

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Background Little is known about risk factors for mortality in older patients with COVID‐19 and neuropsychiatric conditions. Methods We conducted a multicentric retrospective observational study at Assistance Publique‐Hôpitaux de Paris. We selected inpatients aged 70 years or older, with COVID‐19 and preexisting neuropsychiatric comorbidities
Vi‐Huong Nguyen‐Michel, Marion Houot, Cécile Delorme, Aude Sangaré, Ana Gales, Valerio Frazzini, Aurélie Hanin, Djamal Aissani, Thanh Trân, Bruno Oquendo, Flora Ketz, Carmelo Lafuente‐Lafuente, Christel Oasi, Kiyoka Kinugawa, Gaëlle Ouvrard, Renata Ursu, Bertrand Degos, Benjamin Rohaut, Sophie Demeret, Virginie Lambrecq, Vincent Navarro, Emmanuel Fournier, Jean‐Christophe Corvol, Alaina Borden   +23 more
wiley   +1 more source

Multi-scale simulation of thrombus formation at LVAD inlet cannula connection: Importance of Virchow's triad [PDF]

arXiv, 2020
As pump thrombosis is reduced in current-generation ventricular assist devices (VAD), adverse events such as bleeding or stroke remain at unacceptable rates. Thrombosis around the VAD inlet cannula (IC) has been highlighted as a possible source of stroke events.
arxiv