Results 81 to 90 of about 4,582,351 (335)

Safety and Efficacy of Anticoagulation in Patients with Cirrhosis: A Meta-Analysis

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2021
Background and Aims. Portal vein thrombosis is a serious adverse event that occurs during liver cirrhosis. We performed a meta-analysis to evaluate the safety and efficacy of anticoagulant therapy and prophylactic anticoagulant therapy in cirrhosis ...
Huan Chen   +5 more
doaj   +1 more source

Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration

open access: yesAdvanced Materials, EarlyView.
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo   +5 more
wiley   +1 more source

Thromboembolic risk in 16 274 atrial fibrillation patients undergoing direct current cardioversion with and without oral anticoagulant therapy.

open access: yesEuropace, 2015
AIMS To study the risk of thromboembolism in a nationwide cohort of atrial fibrillation patients undergoing direct current (DC) cardioversion with or without oral anticoagulant coverage.
M. L. Hansen   +9 more
semanticscholar   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

open access: yesAdvanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania   +2 more
wiley   +1 more source

Anticoagulant therapy and its impact on dental patients: a review.

open access: yesAustralian dental journal, 2016
Several new oral anticoagulants have been studied in the past decade, and have now started to enter the market. These drugs are reported to be as effective as, or more effective than, warfarin.
D. Thean, Mario Alberghini
semanticscholar   +1 more source

Surface Engineering of Thrombus‐Targeting Nanocarriers for Cardiovascular Diseases: A Short Review

open access: yesAdvanced Materials Interfaces, EarlyView.
This paper systematically introduces surface modification strategies for thrombus‐targeting nanocarriers, highlights the clinical significance of nanocarrier‐based thrombolysis therapies, and prospects the synergy of combing thrombolysis and anti‐inflammatory therapies for enhanced therapeutic effect.
Xinyue Ge   +7 more
wiley   +1 more source

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

open access: yesAdvanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu   +10 more
wiley   +1 more source

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

open access: yesAdvanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao   +17 more
wiley   +1 more source

A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents.

open access: yesNew England Journal of Medicine, 1996
BACKGROUND The clinical benefit of coronary-artery stenting performed in conjunction with coronary angioplasty is limited by the risk of thrombotic occlusion of the stent as well as hemorrhagic and vascular complications of intensive anticoagulation.
A. Schömig   +11 more
semanticscholar   +1 more source

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