Results 121 to 130 of about 227,135 (339)

Comparative Analysis of Antithrombotic Therapy Outcomes in Mild Traumatic Brain-Injury Patients: A Focus on Bleeding Risk and Hospital-Stay Duration

Life
Background: Traumatic brain injury (TBI) in the elderly is a noteworthy pathology due to the exponential increase in population age, and the effects of antiplatelet and anticoagulation on patients’ outcomes are still a matter of dispute.
Antonio Desai, Dana Shiffer, Mauro Giordano, Alice Giotta Lucifero, Elena Generali, Francesco Reggiani, Marta Calatroni, Gabriele Savioli, Sabino Luzzi, Antonio Voza   +9 more
doaj   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

Advanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li, Yong‐Dong Guo, Xiao‐Wen Zhang, Zhi‐Yong Du, Yu‐Qi Wang, Zhuo Yang, Qian‐Wei Luo, Fang‐Fang Zhuo, Tian‐Tian Wei, Zheng‐Ping Liu, Bo Han, Wei Yu, Pei‐Pei Zhang, Wei Zhou, Zhi‐Yuan Lu, Peng‐Fei Tu, Chun‐Hong Zheng, Ke‐Wu Zeng   +17 more
wiley   +1 more source

Intracerebral hematomas during anticoagulant treatment. [PDF]

, 1990
C L Franke, Jeroen de Jonge, John C. van Swieten, A A Op de Coul, J. van Gijn   +4 more
openalex   +1 more source

Postoperative care in finger replantation. Our case-load and review of the literature [PDF]

, 2015
OBJECTIVE: Technical success of a finger replantation depends on several factors such as surgical procedure, type of injury, number of segments amputated, amputation level and individual patient factors.
Chen, Hc, Cigna, Emanuele, LO TORTO, Federico, Maruccia, Michele, Ribuffo, Diego, Ruggieri, M, Zaccheddu, F   +6 more
core  

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

Advanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun, Jiancheng Pan, Rui Li, Ruoxi Li, Ziyan Liu, Jinhui Wu, Tingsheng Lin, Yiqiao Hu, Ahu Yuan   +8 more
wiley   +1 more source

Sangramento durante a anticoagulação oral: alerta sobre um mal maior Sangrado durante la anticoagulación oral: alerta sobre un mal mayor Bleeding during oral anticoagulant therapy: warning against a greater hazard

Arquivos Brasileiros de Cardiologia, 2009
FUNDAMENTO: Sangramento é uma das grandes preocupações em pacientes sob anticoagulação oral. OBJETIVO: Investigar causas determinantes do sangramento em usuários de anticoagulante oral.
Paulo de Lara Lavítola, Guilherme Sobreira Spina, Roney Orismar Sampaio, Flávio Tarasoutchi, Max Grinberg   +4 more
doaj   +1 more source

Prevention of Hemorrhagic Complications After Dental Extractions Into Open Heart Surgery Patients Under Anticoagulant Therapy: The Use of Leukocyte- and Platelet-Rich Fibrin [PDF]

, 2011
Gilberto Sammartino, David M. Dohan Ehrenfest, Francesco Carile, Mariano Tia, Paolo Bucci   +4 more
openalex   +1 more source

Prediction Model for 30-day Outcomes Among Emergency Department Patients with Lower Gastrointestinal Bleeding [PDF]

, 2020
Introduction: There are currently no robust tools available for risk stratification of emergency department (ED) patients with lower gastrointestinal bleed (LGIB).
Leafloor, Cameron, Perry, Jeffrey, Ramaekers, Rosa, Thiruganasambandamoorthy, Venkatesh   +3 more
core  

Mucin‐Inspired Filamentous Sulfated Copolymers Effectively Inhibit Human Respiratory Syncytial Virus (hRSV) Infectivity

Advanced Science, EarlyView.
Virucidal polymers serve as effective antivirals by not only inhibiting viruses but also destroying them. Inspired by the chemical properties of mucin‐mimetics, dendronized polyglycerol‐sulfated, mucin‐inspired amphiphilic copolymers (MIACPs) have been developed.
Raju Bej, Enyu Xie, Kai Ludwig, Robert F. Schmidt, Yannic Kerkhoff, Robert Dalgliesh, Nilanjan Paul, Michael Gradzielski, Andreas Herrmann, Christian Sieben, Rainer Haag   +10 more
wiley   +1 more source

Older patients with pulmonary embolism: a state-of-the-art review

Geriatric Care
Pulmonary embolism (PE) represents one of the main causes of acute respiratory failure in geriatric patients. In the older population, critical issues in PE management are multiple: reduced specificity of clinical signs and symptoms (with symptoms ...
Liliana Mazza, Mariagiovanna Cozza, Francesca Flavia Rossi, Roberto Caragnulo, Giulia Mussatti, Annalisa Paglia, Mattia Brunori, Vincenzo Gianturco, Andrea Rossi, Simone Dini   +9 more
doaj   +1 more source