Results 211 to 220 of about 227,135 (339)

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

Efficacy and safety of anticoagulant therapy in sepsis: A systematic review and meta-analysis. [PDF]

J Int Med Res
Lu J, Zhang Z, Wang L.
europepmc   +1 more source

Contemporary management of atrial fibrillation: what can clinical registries tell us about stroke prevention and current therapeutic approaches? [PDF]

, 2014
Al-Khatib, SM, Banerjee, A, Blendea, D, Camm, AJ, Conroy, JM, Cosio, FG, De Bono, J, G Cosio, MD, Guasch, E, Halperin, JL, Hess, PL, Kirchhof, P, Lip, GY, Nattel, S, Ruskin, J, Savelieva, I   +15 more
core   +1 more source

Macrophage‐targeted cerium‐tannic acid metal‐polyphenol framework nanoenzyme promotes in situ heart valves regeneration through adaptive immunomodulation

BMEMat, EarlyView.
A novel nanoenzyme based on cerium ions‐tannic acid metal‐polyphenol framework (FCT) has been developed and loaded onto DHVs for targeting M1 macrophages to reduce their ROS level and reprogram macrophage phenotype, thereby eliminating inflammation, promoting endothelialization and adaptive matrix remodeling of scaffolds, offering a promising strategy ...
Peng Song, Yunlong Wu, Xing Chen, Yafei Liu, Mengna Dong, Jiawei Shi, Xichi Wang, Nianguo Dong, Weihua Qiao, Qin Wang   +9 more
wiley   +1 more source

AI-ECG for early diagnosis of atrial fibrillation: an under-utilized tool for preemptive stroke prevention. [PDF]

Ann Med Surg (Lond)
Shahid A, Sajid H, Irshad NUN, Imran SB.
europepmc   +1 more source

Anticoagulant Therapy [PDF]

BMJ, 1949
H W, FULLERTON, G, ANASTASOPOULOS
openaire   +2 more sources

Untargeted Metabolomics Reveals Seasonal and Tissue‐Specific Metabolic Shifts in Holothuria cinerascens

Chemistry &Biodiversity, EarlyView.
Untargeted metabolic profiling of three body tissues from Holothuria cinerascens in South Africa using 1H‐NMR and UPLC–QTOF–MS revealed distinct tissue‐specific and seasonal metabolic variations, with the body wall and gut/mesentery exhibiting high metabolite diversity.
Cassandra Upton, Gerhard Prinsloo, Paul Steenkamp, Moses Okpeku   +3 more
wiley   +1 more source

Impact of Anticoagulation Therapy on Healthcare Utilization in Patients With Epistaxis. [PDF]

Laryngoscope Investig Otolaryngol
Andersen B, Kadrie A, Chanamolu M, Gillespie MB.   +3 more
europepmc   +1 more source

5PSQ-015 Prescription errors of anticoagulants

, 2018
Eduard Molins, Belén Rodríguez de Castro, Rubén Pampín Sánchez, Bravo González, Y Labeaga Baramundi, Soledad Rodríguez Nebreda, Raquel Sánchez del Moral   +6 more
openalex   +2 more sources

Endomyocardial Fibrosis Associated With Hypereosinophilic Syndrome: Diagnostic and Management Insights From a Case Report

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Endomyocardial fibrosis (EMF) is a rare form of restrictive cardiomyopathy associated with eosinophilic disorders, characterized by apical subendocardial fibrosis and thrombus formation. Cardiac magnetic resonance (CMR) provides a comprehensive, noninvasive evaluation, enabling diagnosis, assessment of disease activity, and guidance of therapy.
Ibrahim Antoun, Benjamin Marrow, Ravi Pathmanathan, Sanjay S. Bhandari   +3 more
wiley   +1 more source