Abstract Background Epidemiological studies show an increasing incidence of traumatic brain injury (TBI) among people aged 65 years and older. Advances in neurointensive care have improved survival after TBI. There is a need for knowledge about long‐term outcome after TBI among older survivors of TBI.
Charlotta von Seth +4 more
wiley +1 more source
Early Anticoagulation in Large Volume Cardioembolic Stroke: Rethinking the Optimal Initiation Time. [PDF]
Kwon HS, Koh SH.
europepmc +1 more source
Population Pharmacokinetics of Asundexian in People at Risk for Thromboembolic/Cardiovascular Events
ABSTRACT Asundexian is a potent, selective, and reversible inhibitor of activated clotting Factor XI currently under development for secondary prevention of recurrent ischemic stroke in the ongoing Phase III OCEANIC‐STROKE study (NCT05686070). Here, we report the development of a population pharmacokinetic (popPK) model for asundexian.
Ashraf Yassen +7 more
wiley +1 more source
Impact of Anticoagulation Therapy on Healthcare Utilization in Patients With Epistaxis. [PDF]
Andersen B +3 more
europepmc +1 more source
Adherence to anticoagulation management practices.
Charlène Insam +18 more
openalex +2 more sources
This study investigated whether blood cell population data, in addition to cell counts, can identify clinically relevant COPD subgroups. Four distinct inflammatory profiles were identified with distinct clinical characteristics. Cell population data have the potential to provide additional insights beyond inflammatory cell counts and improve patient ...
Pauline J. M. Kuks +6 more
wiley +1 more source
Restarting anticoagulation early versus late in patients with chronic subdural hematoma and atrial fibrillation (RELACS): a phase III international multicenter, randomized controlled, two-arm, assessor-blinded trial. [PDF]
Raj R +23 more
europepmc +1 more source
The Challenges of Vascular Implants: Regulatory Strategies and Biological Responses
Implantable vascular devices are revolutionizing the management of cardiovascular diseases, such as heart failure, by enabling real‐time monitoring and individualized therapy. However, their potential is challenged by regulatory constraints and biological barriers, as device implantation into a vessel can trigger inflammation, thrombosis, and long‐term
Serena Babboni +5 more
wiley +1 more source
Chronic anticoagulation therapy associated with increased complications following hemiarthroplasty in hip fracture patients. [PDF]
Shabani S +6 more
europepmc +1 more source

