Measuring Direct Oral Anticoagulant (DOAC) Levels: Applications, Limitations, and Future Directions
ABSTRACT Introduction There are important challenges with the measurement and interpretation of direct oral anticoagulant (DOAC) anticoagulant effect including a lack of therapeutic ranges, inaccuracy of routinely available coagulation assays, lack of established thresholds for clinically significant effect, and uncertainty about how to apply the ...
Siraj Mithoowani +2 more
wiley +1 more source
Next-Generation Anticoagulants: Precision Strategies for Patient-Centered Thromboprophylaxis. [PDF]
Nasiri A +6 more
europepmc +1 more source
Anticoagulation With Pregnancy In Prosthetic Valves
Muhammad Bilal +2 more
openalex +1 more source
Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley +1 more source
Retained Lumbar Drain Tip Leading to Intrathecal Hematoma: A Case Report on Perioperative Risks and Management. [PDF]
Lee SJ, Gattu K, Sappenfield JW.
europepmc +1 more source
A case of propylthiouracil induced antineutrophil cytoplasmic antibody associated vasculopathy
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Nikhil Dwivedi +2 more
wiley +1 more source
ABSTRACT Introduction The International Society of Thrombosis and Hemostasis (ISTH) guidelines suggest a three‐step evaluation for the detection of lupus anticoagulant (LA), including screening, mixing, and confirmation. According to the guidelines, the LA assay based on activated partial thromboplastin time (APTT) should include an initial screening ...
Bárbara G. Barion +7 more
wiley +1 more source
Pulmonary endarterectomy and lung resection achieving therapeutic success in rarely encountered large cavitary infarctions following pulmonary embolism: a case report. [PDF]
Bakr L +3 more
europepmc +1 more source
ABSTRACT Background Coagulation screening, consisting of prothrombin time (PT) and activated partial prothrombin time (aPTT), is routinely performed in paediatrics to identify bleeding disorders or guide peri‐procedural management. We evaluated the trends in utilisation and diagnostic yield of PT and aPTT testing as part of coagulation screening in a ...
Gerard Gurumurthy +4 more
wiley +1 more source
Tibial vein thrombosis after foam sclerotherapy: A single-institution case series. [PDF]
Donohue JK +7 more
europepmc +1 more source

