Results 21 to 30 of about 334,470 (291)

Early versus Later Anticoagulation for Stroke with Atrial Fibrillation.

New England Journal of Medicine, 2023
BACKGROUND The effect of early as compared with later initiation of direct oral anticoagulants (DOACs) in persons with atrial fibrillation who have had an acute ischemic stroke is unclear.
U. Fischer, M. Koga, D. Strbian, M. Branca, Stefanie Abend, S. Trelle, M. Paciaroni, G. Thomalla, P. Michel, K. Nedeltchev, L. Bonati, G. Ntaios, T. Gattringer, E. Sandset, Peter Kelly, R. Lemmens, P. Sylaja, Diana Aguiar de Sousa, N. Bornstein, Z. Gdovinová, T. Yoshimoto, M. Tiainen, Helen Thomas, M. Krishnan, G. Shim, C. Gumbinger, Jochen Vehoff, Liqun Zhang, K. Matsuzono, E. Kristoffersen, P. Desfontaines, P. Vanacker, Angelika Alonso, Y. Yakushiji, Caterina Kulyk, D. Hemelsoet, Sven Poli, Ana Paiva Nunes, N. Caracciolo, P. Slade, J. Demeestere, A. Salerno, M. Kneihsl, T. Kahles, Daria Giudici, Kanta Tanaka, S. Räty, Rea Hidalgo, D. Werring, Martina B. Göldlin, M. Arnold, Cecilia Ferrari, S. Beyeler, C. Fung, B. Weder, T. Tatlisumak, Sabine Fenzl, Beata Rezny-Kasprzak, A. Hakim, G. Salanti, C. Bassetti, J. Gralla, D. Seiffge, Thomas Horvath, Jesse Dawson   +64 more
semanticscholar   +1 more source

COVID-19 and its implications for thrombosis and anticoagulation

Blood, 2020
Severe acute respiratory syndrome coronavirus 2, coronavirus disease 2019 (COVID-19)-induced infection can be associated with a coagulopathy, findings consistent with infection-induced inflammatory changes as observed in patients with disseminated ...
J. Connors, J. Levy
semanticscholar   +1 more source

Descriptive analysis of patients positive for anti-phospholipid antibodies included in two Italian registries

Bleeding, Thrombosis and Vascular Biology, 2023
The definite diagnosis of antiphospholipid syndrome (APS) depends on the laboratory performance and clinicians’ interpretation. Results from two Italian inception cohort studies of anti-phospholipid antibodies (aPL)-positive subjects, the Italian Survey
Vittorio Pengo, Luca Sarti, Emilia Antonucci, Stefania Di Agostino, Elisa Bison, Gentian Denas, Daniela Poli, Pier Luigi Meroni, Roberto Gerli, Antonella Radice, Gualtiero Palareti, on behalf of FIRMA group and START collaborators   +11 more
doaj   +1 more source

Anticoagulation with edoxaban in patients with long atrial high-rate episodes ≥24 h

European Heart Journal, 2023
Background and Aims Patients with long atrial high-rate episodes (AHREs) ≥24 h and stroke risk factors are often treated with anticoagulation for stroke prevention.
N. Becher, Tobias Toennis, E. Bertaglia, Carina Blomström-Lundqvist, A. Brandes, N. Cabanelas, Melanie Calvert, A. Camm, G. Chlouverakis, G. Dan, W. Dichtl, Hans-Christoph Diener, Alexander Fierenz, A. Goette, J. D. de Groot, A. Hermans, Gregory Y.H Lip, Andrzej Lubinski, E. Marijon, B. Merkely, Lluís Mont, A. Ozga, K. Rajappan, A. Sarkozy, Daniel Scherr, Renate B Schnabel, U. Schotten, S. Sehner, E. Simantirakis, P. Vardas, V. Velchev, D. Wichterle, A. Zapf, P. Kirchhof   +33 more
semanticscholar   +1 more source

Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study

British medical journal, 2021
Objective To evaluate whether early initiation of prophylactic anticoagulation compared with no anticoagulation was associated with decreased risk of death among patients admitted to hospital with coronavirus disease 2019 (covid-19) in the United States.
C. Rentsch, J. Beckman, L. Tomlinson, W. Gellad, C. Alcorn, F. Kidwai-Khan, M. Skanderson, E. Brittain, J. King, Y. Ho, Svetlana K. Eden, S. Kundu, Michael F Lann, R. Greevy, P. Ho, P. Heidenreich, D. Jacobson, I. Douglas, J. Tate, S. Evans, D. Atkins, A. Justice, M. Freiberg   +22 more
semanticscholar   +1 more source

Intermediate-dose anticoagulation, aspirin, and in-hospital mortality in COVID-19: a propensity score-matched analysis

medRxiv, 2021
Background: Thrombotic complications occur at high rates in hospitalized patients with COVID-19, yet the impact of intensive antithrombotic therapy on mortality is uncertain.
Matthew L. Meizlish, George Goshua, Yiwen Liu, Rebecca L. Fine, K. Amin, Eric Chang, Nicholas A. Defilippo, Craig Keating, Yuxin Liu, Michael Mankbadi, Dayna McManus, Stephen Y. Wang, C. Price, R. Bona, C. Chaar, H. Chun, A. Pine, H. Rinder, J. Siner, D. Neuberg, K. Owusu, A. Lee   +21 more
semanticscholar   +2 more sources

Thrombosis and hemostasis at the University of Padua: a reappraisal on the occasion of its 800th year of history

Bleeding, Thrombosis and Vascular Biology, 2022
The year 1222 has traditionally been accepted as the University of Padua’s founding date. The University of Padua is a prestigious center for learning and research, and over the centuries, it has produced luminaries in the most significant disciplines ...
Paolo Simioni, Vittorio Pengo, Paolo Prandoni   +2 more
doaj   +1 more source

No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke [PDF]

, 2012
Background: Dabigatran etexilate (DE) is a new oral direct thrombin inhibitor. Clinical trials point towards a favourable risk-to-benefit profile of DE compared to warfarin. In this study, we evaluated whether hemorrhagic transformation (HT) occurs after
Bohmann, Ferdinand, Förch, Christian, Lindhoff-Last, Edelgard, Mirceska, Ana, Pfeilschifter, Josef Martin (Prof. Dr.), Pfeilschifter, Waltraud, Steinmetz, Helmuth   +6 more
core   +7 more sources

Framework Development for Clinical Comprehensive Evaluation of Drugs–a Study Protocol Using the Delphi Method and Analytic Hierarchy Process

Frontiers in Pharmacology, 2022
Measuring the value of drugs to help make health-care decisions is a complex process which involves confronting trade-offs among multiple objectives. Although guidelines have been released for clinical comprehensive evaluation of drugs, refinement is ...
Chi Zhang, Chi Zhang, Chi Zhang, Er-Li Ma, Bing-Long Liu, Bin Wu, Zhi-Chun Gu, Zhi-Chun Gu, Hou-Wen Lin, Hou-Wen Lin, Hou-Wen Lin   +10 more
doaj   +1 more source

Antithrombotic Therapy in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Undergoing Percutaneous Coronary Intervention: A North American Perspective: 2021 Update.

Circulation, 2021
A growing number of patients undergoing percutaneous coronary intervention (PCI) with stent implantation also have atrial fibrillation. This poses challenges for their optimal antithrombotic management because patients with atrial fibrillation undergoing
D. Angiolillo, Deepak L. Bhatt, C. Cannon, J. Eikelboom, C. Gibson, S. Goodman, C. Granger, D. Holmes, R. Lopes, R. Mehran, D. Moliterno, M. Price, J. Saw, J. Tanguay, D. Faxon   +14 more
semanticscholar   +1 more source