Results 31 to 40 of about 143,755 (261)

Efficacy and safety of anticoagulation in atrial fibrillation patients with intracranial hemorrhage: A systematic review and meta-analysis

Frontiers in Pharmacology, 2023
Background: The benefits and risks of starting anticoagulation therapy, such as direct oral anticoagulations (DOACs) or warfarin, in atrial fibrillation (AF) patients with a history of intracranial hemorrhage (ICH) remain controversial.
Qiang Zhou, Xiang Liu, Xian Yang, Xiao-Hui Huang, Yan-Zi Wu, Ying-Ying Tao, Meng Wei   +6 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Performance of the LumiraDx Platform INR Test in an Anticoagulation Clinic Point-of-Care Setting Compared With an Established Laboratory Reference Method

Clinical and Applied Thrombosis/Hemostasis, 2019
Vitamin K antagonists, such as warfarin, have a narrow therapeutic window; patients on these therapies therefore require regular international normalized ratio (INR) monitoring to maintain optimal dosing.
Robert Campbell Tait BSc, MBChB, FRCP, FRCPath, Annielle Hung MBChB, MRCP, MRCPath, CCST, Roy S. Gardner MBChB, MD, MRCP, FESC, FHFA   +2 more
doaj   +1 more source

Clinical characteristics, management strategies and outcomes of patients with recurrent venous thromboembolism in the real world

Scientific Reports, 2022
There is a paucity of data on management strategies and clinical outcomes after recurrent venous thromboembolism (VTE). In a multicenter registry enrolling 3027 patients with acute symptomatic VTE, the current study population was divided into the ...
Yugo Yamashita, Takeshi Morimoto, Kazushige Kadota, Toru Takase, Seiichi Hiramori, Kitae Kim, Maki Oi, Masaharu Akao, Yohei Kobayashi, Mamoru Toyofuku, Moriaki Inoko, Tomohisa Tada, Po-Min Chen, Koichiro Murata, Yoshiaki Tsuyuki, Yuji Nishimoto, Jiro Sakamoto, Kiyonori Togi, Hiroshi Mabuchi, Kensuke Takabayashi, Takao Kato, Koh Ono, Takeshi Kimura   +22 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Assembly of Bioactive Superstructures via Metal–Phenolic Complexation for Blood Purification

Angewandte Chemie, EarlyView.
Bioactive superstructures are assembled via metal–phenolic‐mediated assembly on agarose templates, followed by modification with human serum albumin. These superstructures demonstrate high bilirubin adsorption efficiency, strong antibacterial activity, and anticoagulant activity, providing a strategy for the rational design of multifunctional blood ...
Po Wang, Jingqu Chen, Siying Chen, Binsha Peng, Zhifeng Zhou, Ling Zhang, Rui Xie, Xiaojie Ju, Wei Wang, Dawei Pan, Liangyin Chu, Frank Caruso, Zhuang Liu   +12 more
wiley   +2 more sources

Secondary thrombosis prevention practice patterns in pediatrics: Results of an international survey

Research and Practice in Thrombosis and Haemostasis, 2022
Background Pediatric venous thromboembolism (VTE) rates continue to increase. Although most children present with transient provoking factors, some have persistent prothrombotic risks beyond the initial treatment period warranting secondary ...
Hope P. Wilson, Rosebella Capio, Inmaculada Aban, Jeffrey Lebensburger, Neil A. Goldenberg   +4 more
doaj   +1 more source

Anticoagulation Before Hospitalization Is a Potential Protective Factor for COVID‐19: Insight From a French Multicenter Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Coronavirus disease 2019 (COVID‐19) is a respiratory disease associated with thrombotic outcomes with coagulation and endothelial disorders. Based on that, several anticoagulation guidelines have been proposed.
Richard Chocron, Vincent Galand, Joffrey Cellier, Nicolas Gendron, Thibaut Pommier, Olivier Bory, Lina Khider, Antonin Trimaille, Guillaume Goudot, Orianne Weizman, Jean Marc Alsac, Laura Geneste, Armand Schmeltz, Vassili Panagides, Aurélien Philippe, Wassima Marsou, Iannis Ben Abdallah, Antoine Deney, Salma El Batti, Sabir Attou, Philippe Juvin, Thomas Delmotte, Emmanuel Messas, Théo Pezel, Benjamin Planquette, Baptiste Duceau, Pascale Gaussem, Willy Sutter, Olivier Sanchez, Victor Waldman, Jean‐Luc Diehl, Tristan Mirault, Guillaume Bonnet, Ariel Cohen, David M. Smadja   +34 more
doaj   +1 more source

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani   +10 more
wiley   +1 more source