Results 21 to 30 of about 188,184 (297)

Warfarin anticoagulation exacerbates the risk of hemorrhagic transformation after rt-PA treatment in experimental stroke: therapeutic potential of PCC [PDF]

, 2011
Background: Oral anticoagulant therapy (OAT) with warfarin is the standard of stroke prevention in patients with atrial fibrillation. Approximately 30% of patients with cardioembolic strokes are on OAT at the time of symptom onset.
Förch, Christian, Waltraud Pfeilschifter, Daniel Spitzer, Pfeilschifter, Josef (Prof. Dr.), Helmuth Steinmetz, Spitzer, Daniel, Steinmetz, Helmuth, Steinmetz Helmuth, Christian Foerch, Pfeilschifter, Waltraud, Josef Pfeilschifter, Pfeilschifter Waltraud, Spitzer Daniel, Foerch Christian, Pfeilschifter Josef   +14 more
core   +2 more sources

Thrombolysis in a stroke patient on dabigatran anticoagulation: case report and synopsis of published cases [PDF]

, 2013
We present the case of an aphasic 77-year-old stroke patient with left distal M1 occlusion who received rt-PA for thrombolysis while on oral anticoagulant treatment with dabigatran (150 mg b.i.d.).
Baas, Horst, Mario Abruscato, Susanne Hövelmann, Pfeilschifter, Waltraud, Abruscato, Mario Giovanni Rosario, Hövelmann, Susanne, Horst Baas, Waltraud Pfeilschifter   +7 more
core   +1 more source

Determinants and clinical outcomes of patients who refused anticoagulation: findings from the global GARFIELD-AF registry

Open Heart, 2023
Objective There is a substantial incidence of stroke in patients with atrial fibrillation (AF) not receiving anticoagulation. The reasons for not receiving anticoagulation are generally attributed to clinician’s choice, however, a proportion of AF ...
Ajay K Kakkar, Keith A A Fox, Sylvia Haas, Saverio Virdone, Jean-Pierre Bassand, Karen S Pieper, Alexander G G Turpie, Gloria Kayani, Seil Oh, Jörn Nielsen, Frank Cools, John Camm, Marianne Brodmann, Patricia Apenteng, Antonio C P Barretto   +14 more
doaj   +1 more source

Unfractionated Heparin and Low-Molecular-Weight Heparin in Sepsis: Anti-Inflammatory and Anticoagulant Effects Versus No Anticoagulation-A Propensity Score-Matched Analysis. [PDF]

J Clin Lab Anal
This propensity score‐matched study compared unfractionated heparin (UFH) and low‐molecular‐weight heparin (LMWH) in 1362 sepsis patients, finding that both significantly improved survival without increasing 90‐day bleeding risk. However, their therapeutic mechanisms differed: UFH demonstrated broader anti‐inflammatory effects by reducing IL‐6, IL‐8 ...
Chen P, Yao Y, Zhao B, An Y, Jiang J, Ma L, Mao E, Wang Y.   +7 more
europepmc   +2 more sources

No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke [PDF]

, 2012
Background: Dabigatran etexilate (DE) is a new oral direct thrombin inhibitor. Clinical trials point towards a favourable risk-to-benefit profile of DE compared to warfarin. In this study, we evaluated whether hemorrhagic transformation (HT) occurs after
Ferdinand Bohmann, Christian Foerch (149410), Edelgard Lindhoff-Last (149408), Ferdinand Bohmann (149406), Mirceska, Ana, Ana Mirceska, Förch, Christian, Waltraud Pfeilschifter, Pfeilschifter, Josef (Prof. Dr.), Bohmann, Ferdinand, Edelgard Lindhoff-Last, Waltraud Pfeilschifter (149411), Helmuth Steinmetz, Steinmetz, Helmuth, Christian Foerch, Helmuth Steinmetz (149409), Pfeilschifter, Waltraud, Josef Pfeilschifter, Josef Pfeilschifter (92946), Ana Mirceska (149407), Lindhoff-Last, Edelgard   +20 more
core   +2 more sources

Changes in anticoagulant prescription in Dutch patients with recent-onset atrial fibrillation: observations from the GARFIELD-AF registry

Thrombosis Journal, 2020
Background For the improvement of AF care, it is important to gain insight into current anticoagulation prescription practices and guideline adherence. This report focuses on the largest Dutch subset of AF-patients, derived from the GARFIELD-AF registry.
J. Seelig, F. W. A. Verheugt, M. E. W. Hemels, L. Illingworth, A. Lucassen, H. Adriaansen, M. C. M. Bongaerts, M. Pieterse, J. P. R. Herrman, P. Hoogslag, W. Hermans, B. E. Groenemeijer, L. V. A. Boersma, K. Pieper, H. ten Cate, on behalf of the GARFIELD-AF Investigators   +15 more
doaj   +1 more source

Fondaparinux Outpatient Use for Patients with a Heparin-Induced Thrombocytopenia History: A Case Report and Review

Pharmacy, 2016
The purpose of this article is to report a case of fondaparinux outpatient utilization for anticoagulation in a patient with a past medical history of heparin-induced thrombocytopenia (HIT) and discuss the options and need for future anticoagulation ...
Amy Christopher
doaj   +1 more source

Anticoagulation [PDF]

, 2022
Thrombotic diseases are some of the leading causes of death in the world. Anticoagulation is a mainstay approach for the prophylaxis and treatment of thrombotic diseases. This book includes six chapters regarding the mechanisms of anticoagulation and its

core   +1 more source

Does High-Dose Thromboprophylaxis Improve Outcomes in COVID-19 Patients? A Meta-analysis of Comparative Studies

TH Open, 2022
Background Thromboembolism remains a detrimental complication of novel coronavirus disease (COVID-19) despite the use of prophylactic doses of anticoagulation Objectives This study aimed to compare different thromboprophylaxis strategies in ...
Maha A. T. Elsebaie, Binav Baral, Mai Elsebaie, Trilok Shrivastava, Catherine Weir, Dennis Kumi, Noah W. Birch   +6 more
doaj   +1 more source

Pharmacogenetics of Anticoagulants [PDF]

Human Genomics and Proteomics, 2010
Warfarin, acenocoumarol, and phenprocoumon are among the major anticoagulant drugs worldwide. Because of their low therapeutic index and serious adverse reactions (ADRs), their wide use, and their varying kinetics and pharmacogenetic dependence, it is of great importance to explore further possibilities to forecast the dose beyond conventional INR ...
Rane, Anders, Lindh, Jonatan D.
openaire   +2 more sources