Results 31 to 40 of about 235,111 (295)

Framework Development for Clinical Comprehensive Evaluation of Drugs–a Study Protocol Using the Delphi Method and Analytic Hierarchy Process

open access: yesFrontiers in Pharmacology, 2022
Measuring the value of drugs to help make health-care decisions is a complex process which involves confronting trade-offs among multiple objectives. Although guidelines have been released for clinical comprehensive evaluation of drugs, refinement is ...
Chi Zhang   +10 more
doaj   +1 more source

Cost-Effectiveness Analysis of Direct Oral Anticoagulants Vs. Vitamin K Antagonists in the Elderly With Atrial Fibrillation: Insights From the Evidence in a Real-World Setting

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: In the clinical setting, the economic benefits of direct oral anticoagulants (DOACs) in elderly patients with atrial fibrillation (AF) remain unclear.
Yue Wu   +7 more
doaj   +1 more source

Antithrombotic Therapy in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Undergoing Percutaneous Coronary Intervention: A North American Perspective: 2021 Update.

open access: yesCirculation, 2021
A growing number of patients undergoing percutaneous coronary intervention (PCI) with stent implantation also have atrial fibrillation. This poses challenges for their optimal antithrombotic management because patients with atrial fibrillation undergoing
D. Angiolillo   +14 more
semanticscholar   +1 more source

Thromboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the anticoagulation forum

open access: yesJournal of Thrombosis and Thrombolysis, 2020
Coronavirus disease 2019 (COVID-19) is a viral infection that can, in severe cases, result in cytokine storm, systemic inflammatory response and coagulopathy that is prognostic of poor outcomes. While some, but not all, laboratory findings appear similar
G. Barnes   +11 more
semanticscholar   +1 more source

Stability of vitamin K antagonist anticoagulation after COVID‐19 diagnosis

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2021
Background Coagulopathy has been reported in severely ill patients with coronavirus disease 2019 (COVID‐19). It is unclear whether outpatients with COVID‐19 who are treated with vitamin K antagonists (VKAs) have unstable anticoagulation.
Eleonora Camilleri   +6 more
doaj   +1 more source

Survival Benefit of Anticoagulation Therapy in End Stage Kidney Disease Patients with Atrial Fibrillation: A Single Center Retrospective Study

open access: yesMedicina, 2021
Background and Objectives: Although the need for anticoagulation to prevent thromboembolism is increasing and non-vitamin K antagonist oral anticoagulants (NOACs) have been tried, there is still controversy about the efficacy of anticoagulation in ...
Mi-Ryung Kim   +8 more
doaj   +1 more source

COVID-19: Coagulopathy, Risk of Thrombosis, and the Rationale for Anticoagulation

open access: yesClinical and applied thrombosis/hemostasis, 2020
The novel coronavirus infection (COVID-19) is caused by the new coronavirus SARS-CoV-2 and is characterized by an exaggerated inflammatory response that can lead to severe manifestations such as adult respiratory syndrome, sepsis, coagulopathy, and death
Wolfgang A. Miesbach, M. Makris
semanticscholar   +1 more source

Determinants and clinical outcomes of patients who refused anticoagulation: findings from the global GARFIELD-AF registry

open access: yesOpen Heart, 2023
Objective There is a substantial incidence of stroke in patients with atrial fibrillation (AF) not receiving anticoagulation. The reasons for not receiving anticoagulation are generally attributed to clinician’s choice, however, a proportion of AF ...
Ajay K Kakkar   +14 more
doaj   +1 more source

Thrombosis, Bleeding, and the Observational Effect of Early Therapeutic Anticoagulation on Survival in Critically Ill Patients With COVID-19

open access: yesAnnals of Internal Medicine, 2021
Hypercoagulability may be a key mechanism of death in patients with COVID-19. This cohort study evaluated the incidence of venous thromboembolism and major bleeding in critically ill patients with COVID-19 and examined the observational effect of early ...
Hanny Al‐Samkari   +334 more
semanticscholar   +1 more source

Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation.

open access: yesNew England Journal of Medicine, 2020
BACKGROUND The roles of anticoagulation alone or with an antiplatelet agent after transcatheter aortic-valve implantation (TAVI) have not been well studied.
V. Nijenhuis   +28 more
semanticscholar   +1 more source

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