Results 51 to 60 of about 230,224 (366)
3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies
Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht +5 more
wiley +1 more source
Frontiers in Pharmacology, 2023 Background: Oral anticoagulants (OACs) are essential for stroke prevention in patients with nonvalvular atrial fibrillation (NVAF). However, the appropriateness of anticoagulation treatment in locally practice remains unclear.
Xiao-Yuan Zheng +9 more
doaj +1 more source
Anticoagulation in patients with atrial fibrillation and heart failure: Insights from the NCDR PINNACLE-AF registry. [PDF]
, 2019 BackgroundIn non-valvular atrial fibrillation (NVAF) patients, congestive heart failure (CHF) confers an increased risk of stroke or systemic thromboembolism.
Cannon, Christopher P +7 more
core +1 more source
Contrast-induced acute kidney injury and renal support for acute kidney injury : a KDIGO summary (part 2) [PDF]
, 2013 Acute kidney injury (AKI) is a common and serious problem affecting millions and causing death and disability for many. In 2012, Kidney Disease: Improving Global Outcomes completed the first ever international multidisciplinary clinical practice ...
Kellum, John A, Lameire, Norbert
core +2 more sources
Advanced Healthcare Materials, EarlyView.This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren +13 more
wiley +1 more source
An NLP Solution to Foster the Use of Information in Electronic Health Records for Efficiency in Decision-Making in Hospital Care [PDF]
arXiv, 2022 The project aimed to define the rules and develop a technological solution to automatically identify a set of attributes within free-text clinical records written in Portuguese. The first application developed and implemented on this basis was a structured summary of a patient's clinical history, including previous diagnoses and procedures, usual ...
arxiv
Advanced Healthcare Materials, EarlyView.An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng +6 more
wiley +1 more source
MOF Coating Enhances the Ion Tolerance of Micromotors
Angewandte Chemie, EarlyView.This work reported a novel method to significantly enhance the ion tolerance of EMNMs using a MOF coating via controllable heteroepitaxial growth, enabling effective motion in high‐salt environments and propulsion through biological tissues under 980 nm NIR light, with potential applications in targeted drug delivery.
Leyan Ou +10 more
wiley +2 more sources
Acta Médica Portuguesa, 2004 Most patients on chronic oral anticoagulant therapy are monitored through anticoagulation clinics, or rather by assistant physicians. Our aim was to compare warfarin anticoagulated patients who were treated with usual medical care (assistant physician ...
Rui Barreira +6 more
doaj +1 more source
Machine learning-assisted search for novel coagulants: when machine learning can be efficient even if data availability is low [PDF]
J. Comput. Chem. 45, No. 13, 937-952 (2024)Design of new drugs is a challenging process: a candidate molecule should satisfy multiple conditions to act properly and make the least side-effect -- perfect candidates selectively attach to and influence only targets, leaving off-targets intact. The amount of experimental data about various properties of molecules constantly grows, promoting data ...
arxiv +1 more source