Results 261 to 270 of about 88,387 (345)

Polymer type effect on microparticle blend of ethyl cellulose, poly(lactic‐co‐glycolic acid) and poly(ε‐caprolactone) for controlled drug delivery with varying solubility

Polymer International, EarlyView.
Preparation, possible microparticles formed, morphology of microparticles and drug release profile from polymeric microparticles. Abstract The objective of this study was to investigate the impact of polymer type on polymeric microparticle blends designed for controlled drug delivery. Microparticle blends containing a single drug (propranolol HCl [Pro]
Muhaimin Muhaimin, Roland Bodmeier
wiley   +1 more source

Extended release huperzine for the treatment of idiopathic epilepsy in dogs - a Case Report. [PDF]

Front Vet Sci
Grant KL, Long SN.
europepmc   +1 more source

The FDA Has Ended Required Blood Monitoring for Clozapine Use—Will This Impact the Management of Parkinson's Disease Psychosis?

Movement Disorders, EarlyView.
Daniel Weintraub, Izabelle Schoen
wiley   +1 more source

Low‐value interventions to deimplement: A secondary analysis of a systematic review of low back pain clinical practice guidelines

PM&R, EarlyView.
Abstract Objective To perform a secondary review of low back pain (LBP) clinical practice guidelines (CPG) identified in a recently conducted systematic review and to synthesize and summarize low‐value recommendations as practices that may be candidates for deimplementation.
Daniel Tai, Eunyeop Kim, Prateek Grover, Alejandro Rodriguez, Timothy J. Olivier, Thiru M. Annaswamy   +5 more
wiley   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Ethnopharmacological Perspective for Treatment of Epilepsy: An Updated Review. [PDF]

Scientifica (Cairo)
Kalra S, Bhatia S, Harrasi AA, Mohan S, Sachdeva H, Sharma D, Budhwar V, Choudhary M, Malik R.   +8 more
europepmc   +1 more source

Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons

Small Science, EarlyView.
This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong, Yanyi Peng, Lingyue Zhang, Bo Xiao, Mengqi Zhang   +4 more
wiley   +1 more source

Continuous video recording with simultaneous amplitude-integrated EEG monitoring to improve seizure recognition in newborns. [PDF]

Front Pediatr
Kage A, Santana YC, Malcolm IL, Francia C, Yoong M, Wertheim D, Shah D.   +6 more
europepmc   +1 more source

Spasmodic Dysphonia

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Spasmodic dysphonia is a laryngeal dystonia that can present as adductor, abductor, or mixed types, with or without tremor. The etiology is not understood fully. Comprehensive evaluation is required to establish the diagnosis. Treatments include voice therapy, medications, botulinum toxin injection, laryngeal surgery, deep brain stimulation ...
Aaron J. Jaworek, Robert T. Sataloff
wiley   +1 more source

The Anticonvulsant Effect of Nonsteroidal Anti-Inflammatory Drug, Fenoprofen, in Pentylenetetrazole-Induced Epileptic Rats: Behavioral, Histological, and Biochemical Evidence. [PDF]

Pharmacol Res Perspect
Rahimi-Tesiye M, Rajabi-Maham H, Azizi V, Hosseini A.   +3 more
europepmc   +1 more source