Duration matters: anticonvulsant therapy linked to bone loss in interim cross-sectional study [PDF]
Consortium PsychiatricumBACKGROUND: Anticonvulsants are widely used in treating patients with mental and neurological disorders. Their long-term use increases the risk of a decrease in bone mineral density (BMD) and low-energy fractures. Despite the growing number of studies of
Natalia A. Sivakova +8 more
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Five years of a single burn center experience with toxic epidermal necrolysis: retrospective study of causative drugs and the clinical outcome [PDF]
Reviews in Clinical Medicine, 2022 Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, but potentially life-threatening reactions to medications. Both conditions have significant morbidity and mortality.
Alireza Sedaghat +5 more
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Reduced Effect of Anticonvulsants on AMPA Receptor Palmitoylation-Deficient Mice
Frontiers in Pharmacology, 2021 AMPA receptors are responsible for fast excitatory synaptic transmission in the mammalian brain. Post-translational protein S-palmitoylation of AMPA receptor subunits GluA1-4 reversibly regulates synaptic AMPA receptor expression, resulting in long ...
Madoka Iizumi +4 more
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Refractory and super-refractory status epilepticus and evidence for the use of ketamine: a scope review [PDF]
Journal of Neurocritical Care, 2023 Status epilepticus (SE) is a neurological emergency with serious consequences for neuronal tissues, therefore, it is considered the most serious manifestation of epilepsy.
Luis Espinosa +3 more
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Role of Anticonvulsants in the Management of AIDS related Seizures
Frontiers in Neurology, 2014 Seventy percent of the AIDS patients have neurological complications. Seizures are one of the complications and can occur at any stage. Seizures can be life–threatening and treatment with anticonvulsants is warranted.
BATOOL F. KIRMANI +1 more
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The Challenges of Children with Bipolar Disorder
Medicina, 2021 Childhood onset bipolar disorder (CO-BD) presents a panoply of difficulties associated with early recognition and treatment. CO-BD is associated with a variety of precursors and comorbidities that have been inadequately studied, so treatment remains ...
Robert M. Post, Heinz Grunze
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Antiepileptic drugs reduce serum uric acid [PDF]
, 1987 Uric acid examination in 554 epileptic out-patients under long-term anticonvulsant medication revealed significantly lower serum concentrations compared to a group of normal controls.
Arab +7 more
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Symptomatic treatment of children with anti-NMDAR encephalitis. [PDF]
, 2016 AIM: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Brilot, F +7 more
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Anticonvulsants Following Craniotomy
Pediatric Neurology Briefs, 1992 A randomized prospective clinical trial of carbamazepine or phenytoin for 6 or 24 months including a control no-treatment group is reported in 276 post-craniotomy patients at the Walton Hospital, Liverpool, England.
J Gordon Millichap
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Teratogenic risk and contraceptive counselling in psychiatric practice: analysis of anticonvulsant therapy [PDF]
, 2013 <p>Background: Anticonvulsants have been used to manage psychiatric conditions for over 50 years. It is recognised that some, particularly valproate, carbamazepine and lamotrigine, are human teratogens, while others including topiramate require ...
A Basan +23 more
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