Role of Anticonvulsants in the Management of Posttraumatic Epilepsy
Posttraumatic seizures have been recognized as a major complication of traumatic brain injury. The annual incidence of traumatic brain injury in the United States is 1.7 million.
Batool F Kirmani, Jason H Huang
exaly +3 more sources
Aim: Anticonvulsant medications are frequently used in clinical practice to treat psychiatric disorders in children and adolescents, but the evidence for their efficacy is uncertain.
Chiara Davico+2 more
exaly +3 more sources
Reduced Effect of Anticonvulsants on AMPA Receptor Palmitoylation-Deficient Mice
AMPA receptors are responsible for fast excitatory synaptic transmission in the mammalian brain. Post-translational protein S-palmitoylation of AMPA receptor subunits GluA1-4 reversibly regulates synaptic AMPA receptor expression, resulting in long ...
Madoka Iizumi+4 more
doaj +1 more source
Refractory and super-refractory status epilepticus and evidence for the use of ketamine: a scope review [PDF]
Status epilepticus (SE) is a neurological emergency with serious consequences for neuronal tissues, therefore, it is considered the most serious manifestation of epilepsy.
Luis Espinosa+3 more
doaj +1 more source
Five years of a single burn center experience with toxic epidermal necrolysis: retrospective study of causative drugs and the clinical outcome [PDF]
Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, but potentially life-threatening reactions to medications. Both conditions have significant morbidity and mortality.
Alireza Sedaghat+5 more
doaj +1 more source
Role of Anticonvulsants in the Management of AIDS related Seizures
Seventy percent of the AIDS patients have neurological complications. Seizures are one of the complications and can occur at any stage. Seizures can be life–threatening and treatment with anticonvulsants is warranted.
BATOOL F. KIRMANI+1 more
doaj +1 more source
Early Administration of Gabapentinoids Improves Motor Recovery after Human Spinal Cord Injury
The anticonvulsant pregabalin promotes neural regeneration in a mouse model of spinal cord injury (SCI). We have also previously observed that anticonvulsants improve motor outcomes following human SCI.
Freda M. Warner+10 more
doaj +1 more source
Comparative vascular effects of levetiracetam and valproate with hyperhomocysteinemia in rat models
Hyperhomocysteinemia (HHcy) a significant risk factor for vascular disease, often emerges in epilepsy with the use of antiepileptic drugs. In this relationship, our study investigates the combined effects of HHcy and antiepileptics on vascular function ...
Gökdemir Selim+6 more
doaj +1 more source
Anticonvulsants and Serum Cholesterol
The effect of antiepileptic drugs (AED) on total cholesterol, high density lipoprotein (HDL) cholesterol and triglycerides was studied in 208 epileptic children compared with 175 normal children at the University of Bologna, Italy.
J Gordon Millichap
doaj +1 more source
Neuropsychological Effects of Anticonvulsants
Investigators from 7 centers in Korea conducted a prospective, multicenter study with patients randomized into two open-label, parallel groups and treated with either levetiracetam (LVT) or carbamazepine (CBZ) monotherapy for newly diagnosed focal ...
Lindsey Morgan, Alexandra Shaw
doaj +1 more source