Duration matters: anticonvulsant therapy linked to bone loss in interim cross-sectional study [PDF]
Consortium PsychiatricumBACKGROUND: Anticonvulsants are widely used in treating patients with mental and neurological disorders. Their long-term use increases the risk of a decrease in bone mineral density (BMD) and low-energy fractures. Despite the growing number of studies of
Natalia A. Sivakova +8 more
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Recurrence of Epilepsy and Related Risk Factors after the Discontinuation of Antiepileptic Drugs in Children: A 10-Year Single-Center Study [PDF]
Annals of Child Neurology, 2021 Purpose The criteria for discontinuing antiepileptic drugs (AEDs) in children with well-controlled epilepsy remain unclear. This study sought to identify the recurrence rate of epilepsy after the discontinuation of AEDs and the risk factors associated ...
Jong Hoon Choi, Sun Jun Kim
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Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study [PDF]
Iranian Journal of Medical Sciences, 2023 Background: Genetic diversity in human leukocyte antigen (HLA) alleles across populations is a significant risk factor for drug-induced severe cutaneous adverse reactions (SCARs), e.g., carbamazepine (CBZ)- and lamotrigine (LTG)-induced Stevens-Johnson ...
Ladan Dastgheib +6 more
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Reduced Effect of Anticonvulsants on AMPA Receptor Palmitoylation-Deficient Mice
Frontiers in Pharmacology, 2021 AMPA receptors are responsible for fast excitatory synaptic transmission in the mammalian brain. Post-translational protein S-palmitoylation of AMPA receptor subunits GluA1-4 reversibly regulates synaptic AMPA receptor expression, resulting in long ...
Madoka Iizumi +4 more
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Role of Anticonvulsants in the Management of AIDS related Seizures
Frontiers in Neurology, 2014 Seventy percent of the AIDS patients have neurological complications. Seizures are one of the complications and can occur at any stage. Seizures can be life–threatening and treatment with anticonvulsants is warranted.
BATOOL F. KIRMANI +1 more
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Antiepileptic drugs reduce serum uric acid [PDF]
, 1987 Uric acid examination in 554 epileptic out-patients under long-term anticonvulsant medication revealed significantly lower serum concentrations compared to a group of normal controls.
Arab +7 more
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Anticonvulsants and Serum Cholesterol
Pediatric Neurology Briefs, 1992 The effect of antiepileptic drugs (AED) on total cholesterol, high density lipoprotein (HDL) cholesterol and triglycerides was studied in 208 epileptic children compared with 175 normal children at the University of Bologna, Italy.
J Gordon Millichap
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Symptomatic treatment of children with anti-NMDAR encephalitis. [PDF]
, 2016 AIM: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Brilot, F +7 more
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Anticonvulsants in pregnancy. [PDF]
Archives of Disease in Childhood, 1991 Epilepsy and pregnancy Recurrent seizures affect at least 1% of women who are of childbearing age, but as the fertility of both men and women with epilepsy is slightly reduced,' about one in 200 pregnancies occurs in a woman with epilepsy. Most of these women are taking anticonvulsants regularly.
C J, Kilpatrick, R F, Moulds
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Neuropsychological Effects of Anticonvulsants
Pediatric Neurology Briefs, 2015 Investigators from 7 centers in Korea conducted a prospective, multicenter study with patients randomized into two open-label, parallel groups and treated with either levetiracetam (LVT) or carbamazepine (CBZ) monotherapy for newly diagnosed focal ...
Lindsey Morgan, Alexandra Shaw
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