Results 91 to 100 of about 71,305 (341)

Long‐term outcomes of epilepsy surgery: A 25‐year experience from a tertiary referral center

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Despite pharmacological advances in epilepsy treatment, one‐third of patients remain pharmacoresistant and may require surgery. Despite extensive literature on epilepsy surgery, studies with follow‐ups longer than 5 years are rare.
Marco Almeida   +6 more
wiley   +1 more source

Consanguinity and rare mutations outside of MCCC genes underlie nonspecific phenotypes of MCCD. [PDF]

open access: yes, 2015
Purpose3-Methylcrotonyl-CoA carboxylase deficiency (MCCD) is an autosomal recessive disorder of leucine catabolism that has a highly variable clinical phenotype, ranging from acute metabolic acidosis to nonspecific symptoms such as developmental delay ...
Barshop, Bruce A   +6 more
core   +1 more source

Volumetric MRI study of the brain in patients with neurocysticercosis and mesial temporal lobe epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Neurocysticercosis (NCC) is a common parasitic infection of the central nervous system and a known cause of focal epilepsy. Its potential role in triggering or contributing to mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is suggested, but the impact on brain volumetry remains unclear.
Jaisa Quedi Araújo   +10 more
wiley   +1 more source

Scientometric assessment of drugs for chronic pain, 1979–2013: rapid growth of publications, paucity of successful drugs [PDF]

open access: yes, 2014
The aim of this study was to find signs of progress in the pharmacotherapy of chronic pain over the past 35 years using scientometric analysis. The following scientometric indices were used: 1) popularity index, representing the share of articles on a ...
Kissin, Igor
core   +1 more source

Synchrotron‐generated microbeams as a radiosurgical alternative for drug‐resistant epilepsies: Proof of concept in a mouse model of mesiotemporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective One‐third of patients with epilepsy, particularly those with mesial temporal lobe epilepsy (MTLE), remain resistant to medication. Resective surgery, the gold standard, is highly invasive and carries significant risks. Here, using a mouse model, we explored the potential of microbeam radiation therapy (MRT), a new technique based on ...
Loan Samalens   +8 more
wiley   +1 more source

Socioeconomic Outcome and Quality of Life in Adults after Status Epilepticus: A Multicenter, Longitudinal, Matched Case–Control Analysis from Germany

open access: yesFrontiers in Neurology, 2017
BackgroundThere is a lack of data concerning socioeconomic outcome and quality of life (QoL) in patients after status epilepticus (SE) in Germany.Patients and methodsAdult patients treated between 2011 and 2015 due to SE at the university hospitals in ...
Lena-Marie Kortland   +6 more
doaj   +1 more source

A review of the aetiology and management of vocal behaviour in dementia [PDF]

open access: yes, 2007
Vocal behaviour is a common form of agitation displayed by people with dementia. It refers to excessive screaming, abusive language, moaning, perseveration, and repetitive and inappropriate requests.
Abela, Stephen   +2 more
core  

P300 component in euthymic patients with bipolar disorder type I, bipolar disorder type II and healthy controls: a preliminary event-related potential study [PDF]

open access: yes, 2015
The aim of the present study was to investigate P300 event-related potential components in euthymic bipolar disorder type I (BDI) and bipolar disorder type II (BDII) patients and matched controls.
BERSANI, FRANCESCO SAVERIO   +8 more
core   +1 more source

Cannabidiol in autism: Clinical pharmacology priorities for trial design

open access: yes
British Journal of Clinical Pharmacology, EarlyView.
Gislei Frota Aragão   +2 more
wiley   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

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