Results 101 to 110 of about 70,021 (342)

Modulation of neural cell membrane conductance by the herbal anxiolytic and antiepileptic drug aswal [PDF]

open access: yes, 2000
To evaluate the effects of aswal on ionic fluxes and neuronal excitation, we performed extracellular and whole cell patch clamp recordings on CA1 pyramidal neurons of guinea pigs and Long-Evans rats.
Grunze, Heinz   +3 more
core   +1 more source

Comparing Outcomes for Telehealth Versus In‐Person Family‐Based Treatment: A Retrospective Chart Review

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Telehealth services have become part of many eating disorder (ED) treatment settings; yet, few studies have examined the effectiveness of family‐based treatment (FBT) delivered via telehealth. This study compared in‐person and telehealth FBT in rates of weight restoration, treatment completion, and metrics of treatment progress, and ...
Catherine R. Drury   +20 more
wiley   +1 more source

Multicomponent Synthesis of Fluorine‐Containing Bioactive Compounds and Drugs

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Multicomponent reactions are robust synthetic tools to assamble complex polyheterocycles and other interesting molecular architectures with potential application in medicinal chemistry, including their fluorine‐containing analogues. Fluorine atoms placed strategically into bioactive molecules often enhance essential pharmacokinetic parameters like ...
Ivette Morales‐Salazar   +7 more
wiley   +1 more source

A review of the aetiology and management of vocal behaviour in dementia [PDF]

open access: yes, 2007
Vocal behaviour is a common form of agitation displayed by people with dementia. It refers to excessive screaming, abusive language, moaning, perseveration, and repetitive and inappropriate requests.
Abela, Stephen   +2 more
core  

Long‐term outcomes of epilepsy surgery: A 25‐year experience from a tertiary referral center

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Despite pharmacological advances in epilepsy treatment, one‐third of patients remain pharmacoresistant and may require surgery. Despite extensive literature on epilepsy surgery, studies with follow‐ups longer than 5 years are rare.
Marco Almeida   +6 more
wiley   +1 more source

MIGRAINE AND EPILEPSY

open access: yesЭпилепсия и пароксизмальные состояния, 2016
Migraine and epilepsy are comorbid neurological diseases that have common clinical and pathophysiological features, as well as common approaches to their treatment.
Yu. E. Azimova, G. R. Tabeeva
doaj  

The pharmacist’s response to the needs of patients undergoing treatment with psychotropic medication [PDF]

open access: yes, 1999
The usage of psychotropic (Table 1) medication is considerable world wide. In Malta, this can be attested to by the numerous studies that have been conducted by the University of Malta Department of Pharmacy (in conjuction with other institutions and ...
Sant Fournier, Mary Ann
core  

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

open access: yesEpilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann   +2 more
wiley   +1 more source

Systemic drug therapy for neuropathic pain

open access: yesRevista Dor
BACKGROUND AND OBJECTIVES: Neuropathic pain involves different etiologies, syndromes, pathophysiologic mechanisms and clinical symptoms, in addition to different treatment modalities.
Lilian Hennemann-Krause, Sidney Sredni
doaj   +1 more source

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