Epilepsia, EarlyView.Abstract Objective Antiseizure medications are approved based on clinical trials that demonstrate their efficacy as measured by reductions in seizure frequency (SF). When designing these trials, trialists must select inclusion criteria where SF can be reliably measured to maintain statistical power.
Wesley T. Kerr +6 more
wiley +1 more source
Review of: "An Investigation of The Phytochemical Richness of Fresh Musa Paradisiaca L. (Plantain) Stem Juice and Its Anticonvulsant Potential on Pentylenetetrazole (Ptz)-Challenged Rats" [PDF]
, 2023 M Deepak
openalex +1 more source
Simulation of Status Epilepticus is Effective Teaching for Junior Neurology Residents [PDF]
, 2020 Purpose: Status Epilepticus (SE) represents a potentially fatal neurologic emergency. At Jefferson, acute management of SE falls to the inpatient neurologist, requiring early competency.
George, Navya +2 more
core +1 more source
In vitro assessment of antimicrobial, antioxidant, and cytotoxic properties of Saccharin-Tetrazolyl and-Thiadiazolyl derivatives: the simple dependence of the pH value on antimicrobial activity [PDF]
, 2019 The antimicrobial, antioxidant, and cytotoxic activities of a series of saccharin-tetrazolyl and -thiadiazolyl analogs were examined. The assessment of the antimicrobial properties of the referred-to molecules was completed through an evaluation of ...
Andrade, Joana M. +9 more
core +1 more source
Epilepsia, EarlyView.Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei +10 more
wiley +1 more source
Optimal approach to standardized documentation in epilepsy clinics: A scoping review
Epilepsia, EarlyView.Abstract Clear documentation and transfer of information between health care providers is key to ensuring the delivery of high‐quality patient care. Our aim was to determine how to optimize and standardize physician documentation in outpatient epilepsy clinics as well as to highlight challenges and barriers to their implementation.
Shahab Marzoughi +8 more
wiley +1 more source
Modulation of neural cell membrane conductance by the herbal anxiolytic and antiepileptic drug aswal [PDF]
, 2000 To evaluate the effects of aswal on ionic fluxes and neuronal excitation, we performed extracellular and whole cell patch clamp recordings on CA1 pyramidal neurons of guinea pigs and Long-Evans rats.
Grunze, Heinz +3 more
core +1 more source
Seizure forecasting with epilepsy cycles: On the causality of forecasting pipelines
Epilepsia, EarlyView.Abstract Objective Seizure risk is modulated by multiscale brain rhythms. Previous studies using cycles in electroencephalography, heart rate, and wearable data suggest the possibility of forecasting seizures days in advance. However, they commonly rely on methods requiring (days of) information from time points beyond the moment of forecast (noncausal
Hongliu Yang +6 more
wiley +1 more source
Scientometric assessment of drugs for chronic pain, 1979–2013: rapid growth of publications, paucity of successful drugs [PDF]
, 2014 The aim of this study was to find signs of progress in the pharmacotherapy of chronic pain over the past 35 years using scientometric analysis. The following scientometric indices were used: 1) popularity index, representing the share of articles on a ...
Kissin, Igor
core +1 more source
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Epilepsia Open, EarlyView.Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source