Results 51 to 60 of about 71,305 (341)
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT A comprehensive synthesis of the broad range of neurodevelopmental and psychiatric manifestations in NF1 is needed to identify knowledge gaps and future directions for NF1 research. In the following scoping review, we identify and summarize the scope of research that examines neurodevelopmental and psychiatric manifestations, both as ...
Meera Chopra +5 more
wiley +1 more source
Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels [PDF]
, 2008 Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-gated sodium channels, decreasing excitability of nerve and muscle cells. Channel inhibition by members of this family of cationic, hydrophobic drugs relies on the presence of highly ...
Ahern, Christopher A. +3 more
core +2 more sources
Effect of Chronic Administration of 5-(3-chlorophenyl)-4-Hexyl-2,4 -Dihydro-3H-1,2,4-Triazole-3-Thione (TP-315)—A New Anticonvulsant Drug Candidate—On Living Organisms [PDF]
, 2021 Anna Makuch‐Kocka +7 more
openalex +1 more source
Timing of Peri‐Ictal MRI Abnormalities in Status Epilepticus – One Size Does Not Fit All
Annals of Neurology, EarlyView.Objective We aimed to investigate timing of occurrence of peri‐ictal MRI abnormalities – a potential risk biomarker of status epilepticus‐related cerebral injury (t2). Methods This prospective study enrolled adult patients with status epilepticus and acute magnetic resonance imaging (MRI); patients with peri‐ictal MRI abnormalities underwent follow‐up ...
Pilar Bosque Varela +12 more
wiley +1 more source
Levetiracetam as a cause of delirium in an elderly patient: a case report
Kerala Journal of Psychiatry, 2018 Levetiracetam is a second generation anticonvulsant. Delirium is not a well-known adverse effect of the drug. We present the report of an 80-year-old woman with past history of schizophrenia for 45 years and memory impairment for two years, who ...
Shahana kasim +3 more
doaj +1 more source
Management of Widespread Pain and Fibromyalgia [PDF]
, 2016 Peer reviewedPublisher ...
Basu, Neil +2 more
core +2 more sources
Asia-Pacific Journal of Chemical Engineering, EarlyView.ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen +5 more
wiley +1 more source
Phenylalanine-Based AMPA Receptor Antagonist as the Anticonvulsant Agent with Neuroprotective Activity—In Vitro and In Vivo Studies [PDF]
, 2022 Gniewomir Latacz +6 more
openalex +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen +4 more
wiley +1 more source
The Challenges of Children with Bipolar Disorder
Medicina, 2021 Childhood onset bipolar disorder (CO-BD) presents a panoply of difficulties associated with early recognition and treatment. CO-BD is associated with a variety of precursors and comorbidities that have been inadequately studied, so treatment remains ...
Robert M. Post, Heinz Grunze
doaj +1 more source