Results 61 to 70 of about 105,937 (401)

Hyperpolarization Modulation of the T‐Type hCav3.2 Channel by Human Synenkephalin [1–53], a Shrew Neurotoxin Analogue without Paralytic Effects

Angewandte Chemie, EarlyView.
Human synenkephalin [1–53] (hSYN), an analogue peptide of shrew saliva neurotoxins, was synthesized and its structural characteristics studied. Synthetic hSYN potently activated the T‐type voltage‐gated Ca channel hCav3.2 but did not paralyze mealworms. These findings offer new insight into neurological disorder treatment and evolutionary mechanisms of
Ryo Fukuoka, Yusuke Yano, Nozomi Hara, Chihiro Sadamoto, Andres D. Maturana, Masaki Kita   +5 more
wiley   +2 more sources

Anticonvulsants-induced chorea: a role for pharmacodynamic drug interaction? [PDF]

, 2001
Chorea is a rare side effect of anticonvulsants. We describe three patients who developed chorea secondary to anticonvulsant combination use. A mechanism to explain this finding is proposed.After identification of an index case with anticonvulsant ...
Beach, Robert L, D'Cruz, O'Neill, Tennison, Michael, Zaatreh, Megdad   +3 more
core   +1 more source

Abnormal Synchronization Between Cortical Delta Power and Ripples in Hippocampal Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Discriminating between epileptogenic and physiological ripples in the hippocampus is important for identifying epileptogenic (EP) zones; however, distinguishing these ripples on the basis of their waveforms is difficult. We hypothesized that the nocturnal synchronization of hippocampal ripples and cortical delta power could be used ...
Takamitsu Iwata, Takufumi Yanagisawa, Ryohei Fukuma, Yuji Ikegaya, Satoru Oshino, Naoki Tani, Hui Ming Khoo, Hidenori Sugano, Yasushi Iimura, Hiroharu Suzuki, Haruhiko Kishima   +10 more
wiley   +1 more source

Isovaleramida, principio anticonvulsivo aislado de Valeriana pavonii

Biomédica: revista del Instituto Nacional de Salud, 2010
Introducción. El fraccionamiento fitoquímico de Valeriana pavonii, especie vegetal nativa utilizada tradicionalmente en Colombia con fines tranquilizantes, condujo al aislamiento e identificación de la isovaleramida, uno de los principios responsables de
Sara Emilia Giraldo, Javier Rincón, Pilar Puebla, Mariel Marder, Cristina Wasowski, Nadezdha Vergel, Mario Francisco Guerrero   +6 more
doaj   +1 more source

Transient lesion in the splenium of the corpus callosum and a sudden antiepileptic drugs withdrawal: A case with focal epilepsy in presurgical evaluation [PDF]

Vojnosanitetski Pregled, 2010
Introduction. A sudden withdrawal of antiepileptic drugs gives higher rate of epileptic seizures in the settings of video electroencephalography (vEEG), monitoring that is a subject to further registration and analysis.
Ristić Aleksandar, Lavrnić Slobodan, Zović Ljubica, Vojvodić Nikola, Janković Slavko, Škrijelj Fadilj, Ercegovac Marko, Sokić Dragoslav   +7 more
doaj   +1 more source

Use of depot medroxyprogesterone acetate and fracture risk [PDF]

, 2010
Depot medroxyprogesterone acetate (DMPA), which has a high rate of use among teenagers in Europe and the United States, has been associated with impaired bone mineral acquisition during adolescence and accelerated bone loss in later life.
Brauchli, Yolanda B., Jick, Susan S., Kraenzlin, Marius E., Meier, Christian, Meier, Christoph R.   +4 more
core   +1 more source

Fluorescence Label‐Free Doxorubicin Sensor Using Polystyrene Sulfonate as a Synthetic Receptor in Whispering Gallery Mode Microresonators

Advanced Sensor Research, EarlyView.
The illustration showcases resonant optical microsensors for Doxorubicin (DXR) detection, using polystyrene sulfonate (PSS) as a synthetic receptor. PSS is deposited as a nanometer‐thick layer on fluorescent microparticles via layer‐by‐layer assembly. DXR‐PSS interaction is depicted, highlighting its effect on the sensor's resonant modes.
Elena Maurina, Algı Domac, Mateusz Olszyna, Lars Dähne, Giuseppe Barillaro   +4 more
wiley   +1 more source

Role of acid‐base and hydration‐dehydration equilibria on reductions of chloral and chloral hydrate

Electrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022
Abstract The electrochemical behavior of chloral hydrate in aqueous solutions at various pH values was investigated by using polarography. Reduction of chloral hydrate takes place in two steps: one appears as a small limiting current value that corresponds to the reduction of the unhydrated form, present in solutions in less than 3%, and another larger
Melek Sirin Baymak
wiley   +1 more source

Epilepsy in the Elderly

International Journal of Gerontology, 2012
Elderly people are the largest and continuously fastest growing population among patients with epilepsy. Elderly patients with epilepsy are very different from other age groups in many respects and clinicians shouldn’t treat them in the same way as ...
Lu-An Chen, Shih-Jung Cheng, Shuo-Bin Jou   +2 more
doaj   +1 more source

Anticonvulsants for tinnitus.

Cochrane Database of Systematic Reviews, 2011
BACKGROUND Tinnitus is the perception of sound or noise in the absence of an external or internal acoustic stimulation. It is a common and potentially distressing symptom for which no adequate therapy exists.
C. Hoekstra, S. Rynja, G. A. van Zanten, M. Rovers   +3 more
semanticscholar   +1 more source