Results 31 to 40 of about 286,539 (338)
Acta Dermato-Venereologica, 2017 There is increasing evidence of clinically relevant anti-inflammatory effects of monoaminergic antidepressants. PubMed and Ovid databases were searched systematically for the use and efficacy of antidepressants in association with 5 common inflammatory ...
Shirin Eskeland +2 more
doaj +1 more source
Understanding Side Effects of Antidepressants: Large-scale Longitudinal Study on Social Media Data
JMIR Mental Health, 2021 BackgroundAntidepressants are known to show heterogeneous effects across individuals and conditions, posing challenges to understanding their efficacy in mental health treatment.
Saha, Koustuv +3 more
doaj +1 more source
‘Never change a winning team’: GPs’ perspectives on discontinuation of long-term antidepressants
Scandinavian Journal of Primary Health Care, 2021 Background Long-term antidepressant use, much longer than recommended by guidelines, can harm patients and generate unnecessary costs. Most antidepressants are prescribed by general practitioners (GPs) but it remains unclear why they do not discontinue ...
Van Leeuwen Ellen +5 more
doaj +1 more source
Effects of Antidepressants on Sleep
Current Psychiatry Reports, 2017 Purpose of ReviewThe aim of this review article was to summarize recent publications on effects of antidepressants on sleep and to show that these effects not only depend on the kind of antidepressant drugs but are also related to the dose, the time of ...
A. Wichniak +3 more
semanticscholar +1 more source
Analgesic Mechanisms of Antidepressants for Neuropathic Pain
International Journal of Molecular Sciences, 2017 Tricyclic antidepressants and serotonin noradrenaline reuptake inhibitors are used to treat chronic pain, such as neuropathic pain. Why antidepressants are effective for treatment of neuropathic pain and the precise mechanisms underlying their effects ...
H. Obata
semanticscholar +1 more source
Should antidepressants be used for major depressive disorder?
BMJ evidence-based medicine, 2019 Background Major depressive disorder is estimated by the WHO to affect more than 300 million people globally, making depression the leading cause of disability worldwide. Antidepressants are commonly used to treat depression. Objective The study aimed to
J. Jakobsen, C. Gluud, I. Kirsch
semanticscholar +1 more source
Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide
Molecular Psychiatry, 2018 Major depressive disorder (MDD) is a common and severe disease characterized by mood changes, somatic alterations, and often suicide. MDD is treated with antidepressants, but the molecular mechanism of their action is unknown.
Anne Gulbins +13 more
semanticscholar +1 more source
Journal of Pain and Symptom Management, 2012 Therapeutic Reviews aim to provide essential independent information for health professionals about drugs used in palliative and hospice care. Additional content is available on www.palliativedrugs.com. Country-specific books (Hospice and Palliative Care Formulary USA, and Palliative Care Formulary, British and Canadian editions) are also available and
Paul, Howard +4 more
openaire +2 more sources
Frontiers in Psychiatry, 2017 BackgroundIn current psychiatric practice, antidepressants are widely and with ever-increasing frequency prescribed to patients. However, several scientific biases obfuscate estimates of antidepressants’ efficacy and harm, and these are barely recognized
Michael P. Hengartner
doaj +1 more source
Network Localization of Fatigue in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source